1-(4-phenylbut-3-ynyl)-2-(1-phenylvinyl)benzene | 1300040-89-4

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二芳基庚烷
• 英文名称: 1-(4-phenylbut-3-ynyl)-2-(1-phenylvinyl)benzene
• 英文别名: 1-(4-Phenylbut-3-ynyl)-2-(1-phenylethenyl)benzene；1-(4-phenylbut-3-ynyl)-2-(1-phenylethenyl)benzene
• CAS: 1300040-89-4
• 化学式: C₂₄H₂₀
• 分子量: 308.423
• InChiKey: BMZCKZGYFYJSES-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.2
• 重原子数：
  24
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1-(4-phenylbut-3-ynyl)-2-(1-phenylvinyl)benzene 在 三氟甲磺酸 作用下， 以 1,2-二氯乙烷 为溶剂， 反应 2.0h， 以82%的产率得到11b-methyl-7-phenyl-6,11b-dihydro-5H-benzo[c]fluorene
  参考文献：
  名称：

  Triflic acid-catalyzed cascade cyclization of arenyl enynes via acetylene-cation cyclization and Friedel–Crafts type reaction

  摘要：

  A novel triflic acid-catalyzed cascade cyclization of arenyl 1,7-enynes through acetylene-cation cyclization followed by Friedel-Crafts reaction has been described. Various fused poly carbocycles can be obtained in good to high yields under mild reaction conditions. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2010.10.094
• 作为产物：
  描述：

  2-溴溴苄 在 manganese(IV) oxide 、 正丁基锂 、 mercury dichloride 作用下， 以 四氢呋喃 为溶剂， 生成 1-(4-phenylbut-3-ynyl)-2-(1-phenylvinyl)benzene
  参考文献：
  名称：

  Triflic acid-catalyzed cascade cyclization of arenyl enynes via acetylene-cation cyclization and Friedel–Crafts type reaction

  摘要：

  A novel triflic acid-catalyzed cascade cyclization of arenyl 1,7-enynes through acetylene-cation cyclization followed by Friedel-Crafts reaction has been described. Various fused poly carbocycles can be obtained in good to high yields under mild reaction conditions. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2010.10.094

文献信息

• Triflic acid-catalyzed cascade cyclization of arenyl enynes via acetylene-cation cyclization and Friedel–Crafts type reaction
  作者：Tienan Jin、Junichi Uchiyama、Masafumi Himuro、Yoshinori Yamamoto

  DOI：10.1016/j.tetlet.2010.10.094

  日期：2011.4

  A novel triflic acid-catalyzed cascade cyclization of arenyl 1,7-enynes through acetylene-cation cyclization followed by Friedel-Crafts reaction has been described. Various fused poly carbocycles can be obtained in good to high yields under mild reaction conditions. (C) 2010 Elsevier Ltd. All rights reserved.