2-[[2-[2-[2-[2-[2-(1-Adamantyloxy)ethoxy]ethoxy]ethoxy]ethylamino]-2-oxoethyl]-[2-[[2-[2-[2-[2-[2-(1-adamantyloxy)ethoxy]ethoxy]ethoxy]ethylamino]-2-oxoethyl]-(carboxymethyl)amino]ethyl]amino]acetic acid | 1187225-55-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-[[2-[2-[2-[2-[2-(1-Adamantyloxy)ethoxy]ethoxy]ethoxy]ethylamino]-2-oxoethyl]-[2-[[2-[2-[2-[2-[2-(1-adamantyloxy)ethoxy]ethoxy]ethoxy]ethylamino]-2-oxoethyl]-(carboxymethyl)amino]ethyl]amino]acetic acid
• 英文别名: 2-[[2-[2-[2-[2-[2-(1-adamantyloxy)ethoxy]ethoxy]ethoxy]ethylamino]-2-oxoethyl]-[2-[[2-[2-[2-[2-[2-(1-adamantyloxy)ethoxy]ethoxy]ethoxy]ethylamino]-2-oxoethyl]-(carboxymethyl)amino]ethyl]amino]acetic acid
• CAS: 1187225-55-3
• 化学式: C₄₆H₇₈N₄O₁₄
• 分子量: 911.144
• InChiKey: GZKCJDQCYWBGBR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.2
• 重原子数：
  64
• 可旋转键数：
  37
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.91
• 拓扑面积：
  213
• 氢给体数：
  4
• 氢受体数：
  16

反应信息

• 作为反应物：
  描述：

  2-[[2-[2-[2-[2-[2-(1-Adamantyloxy)ethoxy]ethoxy]ethoxy]ethylamino]-2-oxoethyl]-[2-[[2-[2-[2-[2-[2-(1-adamantyloxy)ethoxy]ethoxy]ethoxy]ethylamino]-2-oxoethyl]-(carboxymethyl)amino]ethyl]amino]acetic acid 在 三氟乙酸 作用下， 以 二氯甲烷 为溶剂， 以100%的产率得到
  参考文献：
  名称：

  Expression of Sensitized Eu³⁺ Luminescence at a Multivalent Interface

  摘要：

  Assembly of a mixture of guest-functionalized antenna and Eu3+-complexed ligand molecules in a patterned fashion onto a receptor surface provides efficient localized sensitized emission. Coordination of a carboxylate group of the antenna to the Eu3+ center and noncovalent anchoring of both components to the receptor surface appeared to be prerequisites for efficient energy transfer. A Job plot at the surface confirmed that coordination of the antenna to the Eu3+ center occurs in a 1:1 fashion. The efficiency of this intramolecular binding process is promoted by the high effective concentration of both complementary moieties at the surface. The system constitutes therefore an example supramolecular expression of a complex consisting of several different building blocks which signals its own correct formation.

  DOI：

  10.1021/ja904747p
• 作为产物：
  描述：

  乙二胺四乙酸二酐 、 2-(2-(2-(2-(adamantan-1-yloxy)ethoxy)ethoxy)ethoxy)ethanamine 在 三乙胺 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 以80%的产率得到2-[[2-[2-[2-[2-[2-(1-Adamantyloxy)ethoxy]ethoxy]ethoxy]ethylamino]-2-oxoethyl]-[2-[[2-[2-[2-[2-[2-(1-adamantyloxy)ethoxy]ethoxy]ethoxy]ethylamino]-2-oxoethyl]-(carboxymethyl)amino]ethyl]amino]acetic acid
  参考文献：
  名称：

  Expression of Sensitized Eu³⁺ Luminescence at a Multivalent Interface

  摘要：

  Assembly of a mixture of guest-functionalized antenna and Eu3+-complexed ligand molecules in a patterned fashion onto a receptor surface provides efficient localized sensitized emission. Coordination of a carboxylate group of the antenna to the Eu3+ center and noncovalent anchoring of both components to the receptor surface appeared to be prerequisites for efficient energy transfer. A Job plot at the surface confirmed that coordination of the antenna to the Eu3+ center occurs in a 1:1 fashion. The efficiency of this intramolecular binding process is promoted by the high effective concentration of both complementary moieties at the surface. The system constitutes therefore an example supramolecular expression of a complex consisting of several different building blocks which signals its own correct formation.

  DOI：

  10.1021/ja904747p

文献信息

• Expression of Sensitized Eu³⁺ Luminescence at a Multivalent Interface
  作者：Shu-Han Hsu、M. Deniz Yilmaz、Christian Blum、Vinod Subramaniam、David N. Reinhoudt、Aldrik H. Velders、Jurriaan Huskens

  DOI：10.1021/ja904747p

  日期：2009.9.9

  Assembly of a mixture of guest-functionalized antenna and Eu3+-complexed ligand molecules in a patterned fashion onto a receptor surface provides efficient localized sensitized emission. Coordination of a carboxylate group of the antenna to the Eu3+ center and noncovalent anchoring of both components to the receptor surface appeared to be prerequisites for efficient energy transfer. A Job plot at the surface confirmed that coordination of the antenna to the Eu3+ center occurs in a 1:1 fashion. The efficiency of this intramolecular binding process is promoted by the high effective concentration of both complementary moieties at the surface. The system constitutes therefore an example supramolecular expression of a complex consisting of several different building blocks which signals its own correct formation.