Methods for treating benign prostatic hypertrophy (BPH) symptoms using extract from Ageratum spp
申请人:GE Nutrients, Inc.
公开号:US11071763B2
公开(公告)日:2021-07-27
An herbal extract and constituents thereof for treatment of BPH and related aging symptoms in males and for addressing male health using extracts from Ageratum spp., including, but not limited to, Ageratum conyzoides, Ageratum coeruleum and Ageratum houstonianum, is disclosed herein. At least one compound of plants, and parts of plants, of Ageratum spp., such as, but not limited to, N,N-bis(trimethylsilyl)-2-phenyl-7-(trifluoromethyl)quinolon-4-amine, 3′,4′,5′,6′,7′,8-hexamethoxyflavone, Phytol, Precocene, caryophyllene, squalene, alpha-linolenic acid, (Z,Z)-9,12-octadecadienoic acid, Hexadecanoic acid, Hydrocoumarin, Encecaline-1-(7-methoxy-2,2-dimethyl-2H-chromen-6-yl)ethanone, Senensetin-3,4,5,6,7-pentamethoxy flavone, Beta selinene, Stigmasterol, Beta sitosterol, Quercetin, Quercetin-3-O-rhamnosylglucoside, Linoleic acid, or Conyzorigin can be extracted utilizing a Common Plant Extraction Approach (CPEA). The extraction of compounds can be performed utilizing an ethanol solvent and sterile water solvent and/or ethanol mixed with sterile water (i.e., hydro-alcoholic solvents) separately and the concentrated materials obtained as these solvents systems are pooled together (or maintained separately) in order to obtain an herbal extract for the treatment of BPH.
本文公开了一种草本
提取物及其成分,用于治疗男性良性前列腺增生症和相关衰老症状,并利用
龙胆草属植物(包括但不限于Ageratum conyzoides、Ageratum coeruleum和Ageratum houstonianum)的
提取物解决男性健康问题。本文公开了至少一种龙舌兰属植物和植物部分的化合物,如,但不限于,Ageratum conyzoides、Ageratum coeruleum 和 Ageratum houstonianum、例如,但不限于,N,N-双(三
甲基硅基)-2-
苯基-7-(三
氟甲基)
喹啉-4-胺、3′,4′,5′,6′,7′,8-六甲
氧基
黄酮、
植物醇、前胡
烯、
叶黄素、
角鲨烯、α-
亚麻酸、(Z,Z)-9,12-十八
碳二
烯酸、
十六烷酸、
氢化
香豆素、可利用普通植物提取方法 (C
PEA) 提取 Encecaline-1-(7-methoxy-
2,2-dimethyl-2H-chromen-6-yl)ethanone, Senensetin-3,4,5,6,7-pentamethoxy flavone, Beta selinene, Stigmasterol, Beta sitosterol, Quercetin, Quercetin-3-O-rhamnosylglucoside, Linoleic acid 或 Conyzorigin。化合物的提取可分别使用
乙醇溶剂和无菌
水溶剂和/或
乙醇与无菌
水混合溶剂(即
水醇溶剂),然后将这些溶剂系统得到的浓缩物集中在一起(或分别保存),以获得用于治疗良性前列腺增生症的草药
提取物。