3,4',5,6,7-Pentamethoxyflavone | 4472-73-5

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 3,4',5,6,7-Pentamethoxyflavone
• 英文别名: 3,5,6,7-tetramethoxy-2-(4-methoxyphenyl)chromen-4-one
• CAS: 4472-73-5
• 化学式: C₂₀H₂₀O₇
• 分子量: 372.4
• InChiKey: OWNRDLYPIYHOQK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  27
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  72.4
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  3,4',5,6,7-Pentamethoxyflavone 生成 5-Hydroxy-3,6,7-三甲氧基-2-(4-甲氧基苯基)色烯-4-酮
  参考文献：
  名称：

  HORIE, TOKUNARU;KAWAMURA, YASUHIKO;TSUKAYAMA, MASAO;YOSHIZAKI, SHIRO, CHEM. AND PHARM. BULL., 37,(1989) N, C. 1216-1220

  摘要：

  DOI：
• 作为产物：
  描述：

  6-Hydroxy-3,5,7,4'-tetramethoxyflavone 生成 3,4',5,6,7-Pentamethoxyflavone
  参考文献：
  名称：

  HORIE, TOKUNARU;KAWAMURA, YASUHIKO;TSUKAYAMA, MASAO;YOSHIZAKI, SHIRO, CHEM. AND PHARM. BULL., 37,(1989) N, C. 1216-1220

  摘要：

  DOI：

文献信息

• WANG, YING;HAMBURGER, MATTHIAS;GUEHO, JOSEPH;HOSTETTMANN, KURT, PHYTOCHEMISTRY, 28,(1989) N, C. 2323-2327
  作者：WANG, YING、HAMBURGER, MATTHIAS、GUEHO, JOSEPH、HOSTETTMANN, KURT

  DOI：——

  日期：——
• HORIE, TOKUNARU;TSUKAYAMA, MASAO;KAWAMURA, YASUHIKO;SENO, MASAMICHI, J. ORG. CHEM., 52,(1987) N 21, 4702-4709
  作者：HORIE, TOKUNARU、TSUKAYAMA, MASAO、KAWAMURA, YASUHIKO、SENO, MASAMICHI

  DOI：——

  日期：——
• SYSTEMS AND METHODS FOR IDENTIFYING COMBINATIONS OF COMPOUNDS OF THERAPEUTIC INTEREST
  申请人：Califano Andrea

  公开号：US20090269772A1

  公开（公告）日：2009-10-29

  Systems, methods, and apparatus for searching for a combination of compounds of therapeutic interest are provided. Cell-based assays are performed, each cell-based assay exposing a different sample of cells to a different compound in a plurality of compounds. From the cell-based assays, a subset of the tested compounds is selected. For each respective compound in the subset, a molecular abundance profile from cells exposed to the respective compound is measured. Targets of transcription factors and post-translational modulators of transcription factor activity are inferred from the molecular abundance profile data using information theoretic measures. This data is used to construct an interaction network. Variances in edges in the interaction network are used to determine the drug activity profile of compounds in the subset of compounds. The drug activity profiles are used to form a filter set of compound combinations from the subset of compounds.
• Method of Treating Transplant Rejection and Autoimmune Diseases
  申请人：Wisconsin Alumni Research Foundation

  公开号：US20140050694A1

  公开（公告）日：2014-02-20

  A method of treating autoimmune diseases and transplant rejection, comprising the step of treating the autoimmune or transplant patient with an effective amount of SU-5416 is disclosed.
• [EN] EDIBLE BARRIER FILM COMPOSITION<br/>[FR] COMPOSITION DE FILM BARRIÈRE COMESTIBLE
  申请人：[en]APEEL TECHNOLOGY, INC.

  公开号：WO2022212556A1

  公开（公告）日：2022-10-06

  Presented herein are barrier film compositions that can be used, for example, as protective coatings for plant matter (e.g., agricultural products). In some embodiments, the compositions delay moisture loss and/or decrease respiration to extend the shelf life of the plant matter. In one embodiment, the barrier film composition comprises a first component comprising a charged long chain alkyl and a second component having an opposing charge. The barrier film composition can be used to prevent or delay spoilage due to, for instance, desiccation and ripening.