1-(2-nitrophenyl)-N-[2-[(2-nitrophenyl)methylideneamino]cyclohexyl]methanimine | 468087-41-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-(2-nitrophenyl)-N-[2-[(2-nitrophenyl)methylideneamino]cyclohexyl]methanimine
• CAS: 468087-41-4
• 化学式: C₂₀H₂₀N₄O₄
• 分子量: 380.403
• InChiKey: QKHJFYNPGVPCLF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  28
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  116
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  1-(2-nitrophenyl)-N-[2-[(2-nitrophenyl)methylideneamino]cyclohexyl]methanimine 在 盐酸 、 sodium tetrahydroborate 作用下， 以 四氢呋喃 、 氯仿 为溶剂， 反应 3.0h， 生成 N,N'-bis-(2-nitro-benzyl)-cyclohexane-1,2-diaminium dichloride
  参考文献：
  名称：

  N，N-二苄基-环己烷-1,2-二胺衍生物的合成，抗菌活性和构效关系研究

  摘要：

  我们在本文中报道了一系列N，N-二苄基-环己烷-1,2-二胺衍生物的合成和抗菌活性。为了研究取代的二苄基-环己烷-1，2-二胺衍生物的结构-活性关系，合成了44种结构多样的化合物，并针对革兰氏阳性和革兰氏阴性细菌菌株进行了测试。其中，化合物17-20，26，37，38被发现是比MIC值范围0.0005-0.032微克/毫升四环素和在哺乳动物红细胞不溶血高达1024微克/毫升，观察到更活跃。一些化合物还显示出对白念珠菌非常有希望的抗真菌活性，光滑念珠菌和Geotrichum念珠菌。

  DOI：

  10.1016/j.ejmech.2010.11.027
• 作为产物：
  描述：

  1,2-二氨基环己烷 、 邻硝基苯甲醛 以 四氢呋喃 为溶剂， 生成 1-(2-nitrophenyl)-N-[2-[(2-nitrophenyl)methylideneamino]cyclohexyl]methanimine
  参考文献：
  名称：

  N，N-二苄基-环己烷-1,2-二胺衍生物的合成，抗菌活性和构效关系研究

  摘要：

  我们在本文中报道了一系列N，N-二苄基-环己烷-1,2-二胺衍生物的合成和抗菌活性。为了研究取代的二苄基-环己烷-1，2-二胺衍生物的结构-活性关系，合成了44种结构多样的化合物，并针对革兰氏阳性和革兰氏阴性细菌菌株进行了测试。其中，化合物17-20，26，37，38被发现是比MIC值范围0.0005-0.032微克/毫升四环素和在哺乳动物红细胞不溶血高达1024微克/毫升，观察到更活跃。一些化合物还显示出对白念珠菌非常有希望的抗真菌活性，光滑念珠菌和Geotrichum念珠菌。

  DOI：

  10.1016/j.ejmech.2010.11.027

文献信息

• New zinc/tetradentate N 4 ligand complexes: Efficient catalysts for solvent-free preparation of cyclic carbonates by CO 2 /epoxide coupling
  作者：Iyad Karamé、Samira Zaher、Nadim Eid、Lorraine Christ

  DOI：10.1016/j.mcat.2018.07.001

  日期：2018.9

  Tetra-nitrogenated Zn-Schiff-base complexes have been synthetized and studied by X-ray diffraction. The prepared Zn-N4-ligands complexes could not follow the 18-electron rule. This property has allowed the complexes to be efficient in the coordination and activation of the substrates. The zinc complex of N,N’-bis(2-p-tosylaminobenzylidene)-1,2-diaminecyclohexane, Zn(Cy-Ts) combined to tetra-butylammonium

  通过X射线衍射合成和研究了四氮化的Zn-Schiff碱配合物。制备的Zn-N 4-配体配合物不能遵循18电子规则。该性质使得配合物在底物的配位和活化中是有效的。N，N'-双（2-对甲苯磺酰基氨基亚苄基）-1,2-二胺环己烷的锌络合物Zn（Cy-Ts）与碘化四丁铵（TBAI）或与三乙胺的锌络合物，有效地催化了CO 2 /环氧化物的偶联。这些催化反应在没有溶剂的情况下在CO 2压力下于120°C进行。有选择地以高达99％的高收率（TON高达4900）获得环状碳酸酯。CO 2的两个可能途径提出了在没有卤化物干预的情况下β-环氧化物的偶联机理，其中两种反应物都被相同的锌金属中心活化。
• Novel chromium (III) complexes with N4-donor ligands as catalysts for the coupling of CO2 and epoxides in supercritical CO2
  作者：Laia Cuesta-Aluja、Mary Djoufak、Ali Aghmiz、Raquel Rivas、Lorraine Christ、Anna M. Masdeu-Bultó

  DOI：10.1016/j.molcata.2013.10.021

  日期：2014.1

  New neutral and cationic chromium(III) complexes with N4 Schiff base ligands have been prepared and characterized. These complexes are active catalysts for the cycloaddition of CO2 and styrene oxide in CH2Cl2 solutions, affording epoxide conversions in a 39-92% range, with encouraging cyclic carbonate yields (up to 63%). It is to notice that the cationic species were significantly more active than their neutral analogs. Addition of tetrabutylammonium halides improved the selectivity toward styrene carbonate (87% yield). Dichloromethane could be avoided using solvent free or supercritical carbon dioxide as a solvent (scCO(2)) and, moreover, this improved the catalytic activity of the cationic complexes (TOF up to 652h(-1)). Using scCO(2), these chromium catalysts afforded the rapid and selective formation of cyclic carbonates from the coupling of CO2 to various linear terminal epoxides, such as epichlorydrin, propylene oxide and long chain terminal oxiranes. Coupling of cyclohexene oxide and carbon dioxide led to mixtures of poly(cyclohexene) carbonate and cyclic carbonate depending on the conditions (pressure and co-catalyst/catalyst ratio). Poly(cyclohexene) carbonate was isolated with a productivity 388 g/g Cr. Selective formation of the cyclic cyclohexene carbonate was obtained working under scCO(2) conditions. (C) 2013 Elsevier B.V. All rights reserved.
• FUNCTIONALIZED POLYMER AND METHOD FOR MAKING
  申请人：Yan Yuan-Yong

  公开号：US20080154020A1

  公开（公告）日：2008-06-26

  A functionalized polymer includes a directly bonded moiety, which can be located at a terminus of the polymer, defined by the formula —CR 1 R 2 NH-Q-M where M is (N═CR 1 R 2 ) or N-(QN═CR 1 R 2 ) 2 each Q independently is a substituted or unsubstituted, cyclic or acyclic C 1 -C 40 alkyl, aryl, or alkaryl radical, and each R 1 and R 2 independently is a hydrogen atom or a substituted or unsubstituted alkyl, alkenyl, cycloalkyl, cycloalkenyl, aryl, allyl, aralkyl, alkaryl, or alkynyl group. The polymer can be provided by introducing a polyimine compound into a system that includes carbanionic (living) polymer. Such polymers can be used in the production of compositions that include particulate fillers.
• US8853352B2
  申请人：——

  公开号：US8853352B2

  公开（公告）日：2014-10-07