2-[2-[[3-(isocyanatomethyl)-3,5,5-trimethylcyclohexyl]carbamoylamino]-4-methyl-6-oxo-1H-pyrimidin-5-yl]ethyl N-[3-(isocyanatomethyl)-3,5,5-trimethylcyclohexyl]carbamate | 942139-45-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 2-[2-[[3-(isocyanatomethyl)-3,5,5-trimethylcyclohexyl]carbamoylamino]-4-methyl-6-oxo-1H-pyrimidin-5-yl]ethyl N-[3-(isocyanatomethyl)-3,5,5-trimethylcyclohexyl]carbamate
• CAS: 942139-45-9
• 化学式: C₃₁H₄₇N₇O₆
• 分子量: 613.757
• InChiKey: OPZCVFKIFWDAPM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.1
• 重原子数：
  44
• 可旋转键数：
  11
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.74
• 拓扑面积：
  180
• 氢给体数：
  4
• 氢受体数：
  9

反应信息

• 作为产物：
  描述：

  异佛尔酮二异氰酸酯 、 2-氨基-5-(2-羟基乙基)-6-甲基-4(3H)-嘧啶酮 反应 12.0h， 以93%的产率得到2-[2-[[3-(isocyanatomethyl)-3,5,5-trimethylcyclohexyl]carbamoylamino]-4-methyl-6-oxo-1H-pyrimidin-5-yl]ethyl N-[3-(isocyanatomethyl)-3,5,5-trimethylcyclohexyl]carbamate
  参考文献：
  名称：

  Cosmetic compositon comprising a (Thio)urethane/ (thio)urea copolymer capable of forming at least 3 hydrogen bonds, and a method of cosmetic treatment

  摘要：

  本申请涉及化妆品组合物，包括在生理上可接受的介质中，具有（硫）脲/（硫）脲醚聚合物骨架的共聚物，该聚合物骨架是由以下反应产生的：第一单体具有至少两个可聚合基团，可以是相同的或不同的，选择自—N═C═O和—N═C═S；具有至少两个可聚合基团和不稳定氢的单体（b1）；与单体（b1）不同的单体（b2），具有至少两个可聚合基团和不稳定氢，其中至少其中一个单体包含至少一个连接基团（A），能够形成至少3个氢键。本公开还涉及一种角蛋白质材料的化妆品处理方法，包括将上述化妆品组合物应用于所述材料上。

  公开号：

  US20070189991A1

文献信息

• Durable hydrogen bonded hydrogels
  申请人：Suprapolix B.V.

  公开号：US10358521B2

  公开（公告）日：2019-07-23

  This disclosure relates to new injectable hydrogel materials that consist of water gellants comprising linear hydrophilic polymers that comprise hydrogen bonding units in the backbone combined with cross-linkable end groups, resulting in dynamic yet firm hydrogel materials that are easily processable, are highly elastic, show adhesive properties and are self-healing and are especially suitable for biomedical applications.

  本公开涉及新型可注射水凝胶材料，它由亲水性线性聚合物组成的水凝胶剂构成，亲水性线性聚合物的骨架中含有氢键单元，并与可交联的末端基团相结合，从而形成动态而又牢固的水凝胶材料，这种材料易于加工、具有高弹性、粘合性和自愈合性，尤其适合生物医学应用。
• DURABLE HYDROGEN BONDED HYDROGELS
  申请人：Suprapolix B.V.

  公开号：US20170210843A1

  公开（公告）日：2017-07-27

  This disclosure relates to new injectable hydrogel materials that consist of water gellants comprising linear hydrophilic polymers that comprise hydrogen bonding units in the backbone combined with cross-linkable end groups, resulting in dynamic yet firm hydrogel materials that are easily processable, are highly elastic, show adhesive properties and are self-healing and are especially suitable for biomedical applications.
• [EN] DURABLE HYDROGEN BONDED HYDROGELS<br/>[FR] HYDROGELS À LIAISON HYDROGÈNE DURABLES
  申请人：SUPRAPOLIX BV

  公开号：WO2016018145A1

  公开（公告）日：2016-02-04

  This invention relates to new injectable hydrogel materials that consist of water gellants comprising linear hydrophilic polymers that comprise hydrogen bonding units in the backbone combined with cross-linkable end groups, resulting if dynamic yet firm hydrogel materials that are easily processable, are highly elastic, show adhesive properties and are self-healing and are especially suitable for biomedical applications.
• Cosmetic compositon comprising a (Thio)urethane/ (thio)urea copolymer capable of forming at least 3 hydrogen bonds, and a method of cosmetic treatment
  申请人：Mougin Nathalie

  公开号：US20070189991A1

  公开（公告）日：2007-08-16

  The present application relates to cosmetic compositions comprising, in a physiologically acceptable medium, a copolymer having a (thio)urethane/(thio)urea polymer skeleton, resulting from the reaction: of a first monomer having at least two polymerizable groups, which may be identical or different, chosen from —N═C═O and —N═C═S, of a monomer (b1) having at least two polymerizable groups with a labile hydrogen, of a monomer (b2), different from monomer (b1), having at least two polymerizable groups with a labile hydrogen, with at least one of these monomers comprising at least one junction group (A), capable of forming at least 3 hydrogen bonds. The disclosure also relates to a method of cosmetic treatment of keratinous materials, comprising the application of a cosmetic composition as defined above on said materials.

  本申请涉及化妆品组合物，包括在生理上可接受的介质中，具有（硫）脲/（硫）脲醚聚合物骨架的共聚物，该聚合物骨架是由以下反应产生的：第一单体具有至少两个可聚合基团，可以是相同的或不同的，选择自—N═C═O和—N═C═S；具有至少两个可聚合基团和不稳定氢的单体（b1）；与单体（b1）不同的单体（b2），具有至少两个可聚合基团和不稳定氢，其中至少其中一个单体包含至少一个连接基团（A），能够形成至少3个氢键。本公开还涉及一种角蛋白质材料的化妆品处理方法，包括将上述化妆品组合物应用于所述材料上。