26,28-Bis(phenylmethoxy)-27-propoxypentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(25),3(28),4,6,9(27),10,12,15,17,19(26),21,23-dodecaen-25-ol | 1374220-00-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 26,28-Bis(phenylmethoxy)-27-propoxypentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(25),3(28),4,6,9(27),10,12,15,17,19(26),21,23-dodecaen-25-ol
• CAS: 1374220-00-4
• 化学式: C₄₅H₄₂O₄
• 分子量: 646.826
• InChiKey: RPISRGYIOJBIPA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  11.1
• 重原子数：
  49
• 可旋转键数：
  9
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  47.9
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  26,28-Bis(phenylmethoxy)-27-propoxypentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(25),3(28),4,6,9(27),10,12,15,17,19(26),21,23-dodecaen-25-ol 在 iron(III) chloride hexahydrate 作用下， 以 乙腈 为溶剂， 反应 2.5h， 生成
  参考文献：
  名称：

  Tubular Conjugated Polymer for Chemosensory Applications

  摘要：

  In this paper, we present the concept of a soluble tubular conjugated polymer (TCP). We report on a fluorescent 5,5'-Bicalixarene-based polymer where the calixarene units are seamlessly incorporated in the conjugated polymeric chain that can respond to a small molecule complexation inside the hydrophobic cavity. In particular, our system demonstrated a reversible rapid fluorescence quenching upon interaction of gaseous nitric oxide with the calixarene moiety.

  DOI：

  10.1021/ja301918f
• 作为产物：
  描述：

  25,27-bis(benzyloxy)-26,28-dihydroxycalix[4]arene 、 1-碘代丙烷 在 sodium hydride 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 24.25h， 以64%的产率得到26,28-Bis(phenylmethoxy)-27-propoxypentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(25),3(28),4,6,9(27),10,12,15,17,19(26),21,23-dodecaen-25-ol
  参考文献：
  名称：

  Tubular Conjugated Polymer for Chemosensory Applications

  摘要：

  In this paper, we present the concept of a soluble tubular conjugated polymer (TCP). We report on a fluorescent 5,5'-Bicalixarene-based polymer where the calixarene units are seamlessly incorporated in the conjugated polymeric chain that can respond to a small molecule complexation inside the hydrophobic cavity. In particular, our system demonstrated a reversible rapid fluorescence quenching upon interaction of gaseous nitric oxide with the calixarene moiety.

  DOI：

  10.1021/ja301918f

文献信息

• Fluorescent Calixarene Scaffolds for NO Detection in Protic Media
  作者：Brij Bhushan Ahuja、Arkadi Vigalok

  DOI：10.1002/anie.201813589

  日期：2019.2.25

  water‐soluble conjugated calixarene scaffolds that are capable of NO gas detection. Two different scaffolds, one based on a 5,5′‐bicalixarene structure and its isomer bearing two distantly conjugated calixarene moieties, were synthesized. While the fluorescence of both isomers is quenched upon either passing of NO gas or generating it in situ from diethylamine NONOate, the bicalixarene‐based scaffold showed

  我们介绍了首个能够检测NO气体的荧光水溶性共轭杯芳烃支架。合成了两种不同的支架，一种基于5,5'-bicalixarene结构，其异构体带有两个远共轭的杯芳烃部分。尽管两种异构体的荧光在NO气体通过或由二乙胺NONOate原位生成时均被淬灭，但基于比卡西林的支架显示出明显更强的响应。我们还提供了一个染料包封策略的示例，该示例可以实现比亲本杯芳烃主体更长的波长下的NO的检测。最后，还制备了带有5,5'-比卡西芳烃骨架的共轭聚合物，并由于分子线效应，与单体相比具有更高的灵敏度。
• Carbazole-fused calixarene cavities: single and mixed AIEgen systems for NO detection
  作者：Varun Rawat、Abhishek Baheti、Om Shanker Tiwari、Arkadi Vigalok

  DOI：10.1039/d3cc01181j

  日期：——

  Novel oxygen-depleted calix[4]arenes containing fused carbazole moieties demonstrate AIEgen behavior in aqueous solutions, leading to highly sensitive detection of NO guest by affecting intra- and intermolecular energy transfer within the...

  含有融合咔唑分子的新型缺氧钙[4]烷在水溶液中表现出 AIEgen 行为，通过影响分子内和分子间的能量转移，实现了对 NO 客体的高灵敏度检测。