2-(3-methoxyphenoxy)ethanaldehyde | 135360-34-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 2-(3-methoxyphenoxy)ethanaldehyde
• 英文别名: 2-(3-methoxyphenoxy)acetaldehyde
• CAS: 135360-34-8
• 化学式: C₉H₁₀O₃
• 分子量: 166.177
• InChiKey: VXORHBJUOBJMDC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-(3-methoxyphenoxy)ethanaldehyde 在 4-二甲氨基吡啶 、 吡啶硼烷 、 盐酸羟胺 、 三乙胺 作用下， 以 吡啶 、 甲醇 、 乙醇 为溶剂， 反应 10.17h， 生成 乙酰胺,N-羟基-N-[2-(3-甲氧基苯氧基)乙基]-
  参考文献：
  名称：

  Svoboda, Jiri; Palecek, Jaroslav, Collection of Czechoslovak Chemical Communications, 1991, vol. 56, # 6, p. 1317 - 1332

  摘要：

  DOI：
• 作为产物：
  描述：

  2-(3-甲氧基苯氧基)乙酸甲酯 在 盐酸 、 二异丁基氢化铝 作用下， 生成 2-(3-methoxyphenoxy)ethanaldehyde
  参考文献：
  名称：

  Svoboda, Jiri; Palecek, Jaroslav, Collection of Czechoslovak Chemical Communications, 1991, vol. 56, # 6, p. 1317 - 1332

  摘要：

  DOI：

文献信息

• NOVEL CASPASE INHIBITORS
  申请人：RIJKSUNIVERSITEIT GRONINGEN

  公开号：EP3666769A1

  公开（公告）日：2020-06-17

  The present invention provides novel compounds of formula (I) that are potent and selective non-covalent caspase inhibitors. These compounds nay be used for the treatment of inflammatory diseases.

  本发明提供了新型的式 (I) 化合物，它们是强效和选择性的非共价 Caspase 抑制剂。这些化合物可用于治疗炎症性疾病。
• Bi-functional complexes and methods for making and using such complexes
  申请人：Gouliaev Alex Haahr

  公开号：US11225655B2

  公开（公告）日：2022-01-18

  The present invention is directed to a method for the synthesis of a bi-functional complex comprising a molecule part and an identifier oligonucleotide part identifying the molecule part. A part of the synthesis method according to the present invention is preferably conducted in one or more organic solvents when a nascent bi-functional complex comprising an optionally protected tag or oligonucleotide identifier is linked to a solid support, and another part of the synthesis method is preferably conducted under conditions suitable for enzymatic addition of an oligonucleotide tag to a nascent bi-functional complex in solution.

  本发明涉及一种合成双功能复合物的方法，该复合物包括分子部分和识别分子部分的识别寡核苷酸部分。根据本发明的合成方法的一部分优选在一种或多种有机溶剂中进行，此时包含可选保护标签或寡核苷酸标识符的新生双功能复合物与固体支持物相连接，合成方法的另一部分优选在适合于将寡核苷酸标签酶加到溶液中的新生双功能复合物的条件下进行。
• BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES
  申请人：Nuevolution A/S

  公开号：EP2558577A1

  公开（公告）日：2013-02-20
• BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES
  申请人：Gouliaev Alex Haahr

  公开号：US20130281324A1

  公开（公告）日：2013-10-24

  The present invention is directed to a method for the synthesis of a bi-functional complex comprising a molecule part and an identifier oligonucleotide part identifying the molecule part. A part of the synthesis method according to the present invention is preferably conducted in one or more organic solvents when a nascent bi-functional complex comprising an optionally protected tag or oligonucleotide identifier is linked to a solid support, and another part of the synthesis method is preferably conducted under conditions suitable for enzymatic addition of an oligonucleotide tag to a nascent bi-functional complex in solution.
• [EN] BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES<br/>[FR] COMPLEXES BIFONCTIONNELS ET PROCÉDÉS DE FABRICATION ET D'UTILISATION DE TELS COMPLEXES
  申请人：NUEVOLUTION AS

  公开号：WO2011127933A1

  公开（公告）日：2011-10-20

  The present invention is directed to a method for the synthesis of a bi-functional complex comprising a molecule part and an identifier oligonucleotide part identifying the molecule part. A part of the synthesis method according to the present invention is preferably conducted in one or more organic solvents when a nascent bi-functional complex comprising an optionally protected tag or oligonucleotide identifier is linked to a solid support, and another part of the synthesis method is preferably conducted under conditions suitable for enzymatic addition of an oligonucleotide tag to a nascent bi-functional complex in solution.