6,6'-Bis-(2-allyloxy-ethylsulfanyl)-[2,2']bipyridinyl | 872353-37-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 6,6'-Bis-(2-allyloxy-ethylsulfanyl)-[2,2']bipyridinyl
• 英文别名: 2-(2-Prop-2-enoxyethylsulfanyl)-6-[6-(2-prop-2-enoxyethylsulfanyl)pyridin-2-yl]pyridine
• CAS: 872353-37-2
• 化学式: C₂₀H₂₄N₂O₂S₂
• 分子量: 388.555
• InChiKey: KLWLKXFBEITWIH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  26
• 可旋转键数：
  13
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  94.8
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  6,6'-Bis-(2-allyloxy-ethylsulfanyl)-[2,2']bipyridinyl 在 Grubbs catalyst first generation 作用下， 以 二氯甲烷 为溶剂， 反应 6.0h， 生成 (Z)-10,15-Dioxa-7,18-dithia-23,24-diaza-tricyclo[17.3.1.1^2,6]tetracosa-1(23),2(24),3,5,12,19,21-heptaene 、 (E)-10,15-Dioxa-7,18-dithia-23,24-diaza-tricyclo[17.3.1.1^2,6]tetracosa-1(23),2(24),3,5,12,19,21-heptaene
  参考文献：
  名称：

  S-Transalkylation/ring closing metathesis as a route to azathiamacrocycles incorporating 2,2′-bipyridine subunits

  摘要：

  A new route to cyclophanes 6a,b incorporating 2,2'-bipyridine subunits has been elaborated using as the key steps (1) S-transalkylation of 6.6'-bis(methylsulfyl)-2,2'-bipyridines 2a,b with ethyl bromoacetate resulting in the formation of 6,6'-bis[(ethoxycarbonyl)methylsulfanyl]-2.2'-bipyridines 3a,b and (2) ring-closing metathesis of the corresponding alkenyl ethers 5a,b. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2005.10.003
• 作为产物：
  描述：

  6,6'-bis(methylsulfanyl)-2,2'-bipyridine 在 lithium aluminium tetrahydride 、 sodium hydride 作用下， 以 四氢呋喃 、 N,N-二甲基甲酰胺 为溶剂， 反应 25.0h， 生成 6,6'-Bis-(2-allyloxy-ethylsulfanyl)-[2,2']bipyridinyl
  参考文献：
  名称：

  S-Transalkylation/ring closing metathesis as a route to azathiamacrocycles incorporating 2,2′-bipyridine subunits

  摘要：

  A new route to cyclophanes 6a,b incorporating 2,2'-bipyridine subunits has been elaborated using as the key steps (1) S-transalkylation of 6.6'-bis(methylsulfyl)-2,2'-bipyridines 2a,b with ethyl bromoacetate resulting in the formation of 6,6'-bis[(ethoxycarbonyl)methylsulfanyl]-2.2'-bipyridines 3a,b and (2) ring-closing metathesis of the corresponding alkenyl ethers 5a,b. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2005.10.003

文献信息

• S-Transalkylation/ring closing metathesis as a route to azathiamacrocycles incorporating 2,2′-bipyridine subunits
  作者：Danuta Branowska、Izabela Buczek、Katarzyna Kalińska、Justyna Nowaczyk、Andrzej Rykowski

  DOI：10.1016/j.tetlet.2005.10.003

  日期：2005.12

  A new route to cyclophanes 6a,b incorporating 2,2'-bipyridine subunits has been elaborated using as the key steps (1) S-transalkylation of 6.6'-bis(methylsulfyl)-2,2'-bipyridines 2a,b with ethyl bromoacetate resulting in the formation of 6,6'-bis[(ethoxycarbonyl)methylsulfanyl]-2.2'-bipyridines 3a,b and (2) ring-closing metathesis of the corresponding alkenyl ethers 5a,b. (c) 2005 Elsevier Ltd. All rights reserved.