3-Hexin-1,6-dithiol | 115465-35-5

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醇
• 英文名称: 3-Hexin-1,6-dithiol
• 英文别名: 3-hexyne-1,6-dithiol；Hex-3-yne-1,6-dithiol
• CAS: 115465-35-5
• 化学式: C₆H₁₀S₂
• 分子量: 146.277
• InChiKey: YYLZFVAZIBYRMJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  8
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  2
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  3-Hexin-1,6-dithiol 在 sodium hydroxide 、 sodium hydride 作用下， 以 四氢呋喃 、 乙醇 、 二氯甲烷 为溶剂， 反应 49.5h， 生成 1,6-Di(thiomethyl)-3-hexin
  参考文献：
  名称：

  Brudermueller, Martin; Musso, Hans; Wagner, Alfred, Chemische Berichte, 1988, vol. 121, p. 2239 - 2244

  摘要：

  DOI：
• 作为产物：
  描述：

  hex-3-yne-1,6-diyl bis(4-methylbenzenesulfonate) 在 碳酸氢钠 、 硫脲 、 lithium bromide 作用下， 以 丙酮 为溶剂， 反应 20.0h， 生成 3-Hexin-1,6-dithiol
  参考文献：
  名称：

  Brudermueller, Martin; Musso, Hans; Wagner, Alfred, Chemische Berichte, 1988, vol. 121, p. 2239 - 2244

  摘要：

  DOI：

文献信息

• Suppository and composition comprising at least one polyethylene glycol
  申请人：Anestic ApS

  公开号：US20020048601A1

  公开（公告）日：2002-04-25

  There is provided a suppository comprising at least one biocompatible polymer, wherein the biocompatible polymer is essentially non-biodegradable, and wherein the suppository essentially does not swell when contacted with an aqueous fluid. The suppository may further comprise a plurality of open cells at least partly separated from one another by an interpenetrating matrix comprising at least one biocompatible polymer in branched or crosslinked form. The plurality of interlinked, open cells are capable of containing an aqueous fluid, and the permeability of the suppository ensures that entry of body fluids into the open cells under practical circumstances occurs essentially without dehydration of mucousal membrane tissue contacting the suppository. The suppository furthermore preferably comprises a controlled release formulation.

  提供了一种含有至少一种生物相容性聚合物的栓剂，其中该生物相容性聚合物基本上不可生物降解，且当与水性液体接触时，该栓剂基本上不膨胀。该栓剂还可以进一步包括多个开放单元，这些单元至少部分地由相互穿插的基质分隔开，该基质包含至少一种分支或交联形式的生物相容性聚合物。这些互相连接的开放单元能够包含水性液体，而栓剂的渗透性确保体液进入开放单元时，在实际情况下基本上不会导致接触栓剂的粘膜组织脱水。此外，该栓剂最好包含控制释放配方。
• Polymer dispersions in polyols containing unsaturation
  申请人：THE DOW CHEMICAL COMPANY

  公开号：EP0000503A1

  公开（公告）日：1979-02-07

  This invention is directed to stable dispersions of copolymers in polyols containing added unsaturation. The polymer dispersions are prepared by reacting a polyol containing added ethylenic unsaturation and an ethylenically unsaturated monomer or mixtures thereof in the presence of a free radical catalyst characterized in that the dispersion is prepared by the Williamson synthesis or a phase transfer catalyst modification thereof employing in situ polymerization of the ethylenically unsaturated monomer or mixtures thereof in the polymer containing added ethylenic unsaturation. The unsaturated polyals prepared by these methods may be used alone or they may be blended with polyols not containing added unsaturation. The dispersions are relatively low viscosity liquids which are useful in the preparation of polyurethanes such as, for example foams and elastomers.

  This invention is directed to stable dispersions of copolymers in polyols containing added unsaturation. The polymer dispersions are prepared by reacting a polyol containing added ethylenic unsaturation and an ethylenically unsaturated monomer or mixtures thereof in the presence of a free radical catalyst characterized in that the dispersion is prepared by the Williamson synthesis or a phase transfer catalyst modification thereof employing in situ polymerization of the ethylenically unsaturated monomer or mixtures thereof in the polymer containing added ethylenic unsaturation. The unsaturated polyals prepared by these methods may be used alone or they may be blended with polyols not containing added unsaturation. The dispersions are relatively low viscosity liquids which are useful in the preparation of polyurethanes such as, for example foams and elastomers.
• Process for the preparation of carbodiimide-isocyanurate foams employing quaternary boron salts as catalysts
  申请人：BASF WYANDOTTE CORPORATION

  公开号：EP0001261A1

  公开（公告）日：1979-04-04

  Rigid foams characterized by carbodiimide and isocyanurate linkages are prepared by catalytically condensing an organic polyisocyanate in the presence of certain quaternary boron salts.

  在某些季硼酸盐存在的情况下，通过催化缩合有机多异氰酸酯，可制备出以碳化二亚胺和异氰尿酸酯连接为特征的硬质泡沫。
• High resilience flexible foamed polyurethanes, foamable mixtures and process therefor
  申请人：BASF WYANDOTTE CORPORATION

  公开号：EP0003210A1

  公开（公告）日：1979-08-08

  A flexible, highly resilient, cold-cure, closed-mold polyurethane foam can be produced by reacting a foamable mixture comprising an organic isocyanate, water and a polyol. The foams of the invention are preferably prepared from a mixture of a hydroxyl-terminated graft copolymer and a hydroxyl-terminated polyoxyalkylene polyether in the presence of a co-catalyst mixture of at least one tertiary amine catalyst and at least one metal-containing basic catalyst. Said catalyst is selected from the group consisting of an alkali metal hydroxide, an alkaline earth metal hydroxide, an inorganic basic salt thereof derived from the reaction of said hydroxides with a weak inorganic acid, a metal organic basic salt catalyst derived from the reaction of at least one of said hydroxides with an organic acid and mixtures thereof. Useful metal organic catalysts are selected from the group consisting of the alkali and alkaline earth metal carboxylates, alkoxides and phenates. Useful inorganic basic metal salt catalysts are sodium bicarbonate and sodium carbonate.

  通过对由有机异氰酸酯、水和多元醇组成的可发泡混合物进行反应，可生产出柔性、高回弹性、冷固化、闭模聚氨酯泡沫塑料。本发明的泡沫最好由羟基封端接枝共聚物和羟基封端聚氧亚烷基聚醚的混合物在至少一种叔胺催化剂和至少一种含金属的碱性催化剂的助催化剂混合物存在下制备而成。所述催化剂选自碱金属氢氧化物、碱土金属氢氧化物、由所述氢氧化物与弱无机酸反应生成的无机碱性盐、由至少一种所述氢氧化物与有机酸反应生成的金属有机碱性盐催化剂及其混合物组成的组。有用的金属有机催化剂选自碱金属和碱土金属羧酸盐、烷氧基化物和苯酸盐组成的组。有用的无机碱金属盐催化剂是碳酸氢钠和碳酸钠。
• Process for the preparation of carbodiimide-isocyanurate foams
  申请人：BASF WYANDOTTE CORPORATION

  公开号：EP0002281A1

  公开（公告）日：1979-06-13

  Rigid foams characterized by carbodiimide and isocyanurate linkages are prepared by catalytically condensing an organic polyisocyanate in the presence of (a) a carbodiimide-promoting compound and (b) certain C1-C8 alkali metal carboxylates as trimerization catalysts.

  硬质泡沫的特点是碳化二亚胺和异氰尿酸酯连接，其制备方法是在(a)碳化二亚胺促进化合物和(b)作为三聚催化剂的某些 C1-C8 碱金属羧酸盐存在下催化缩合有机多异氰酸酯。