Dimethyl-((E)-1-methylsulfanyl-2-nitro-vinyl)-amine | 42506-12-7

• 分子结构分类: 有机化合物 - 有机1,3-偶极化合物 - 烯丙基型1,3-偶极有机化合物
• 英文名称: Dimethyl-((E)-1-methylsulfanyl-2-nitro-vinyl)-amine
• 英文别名: 1-Dimethylamino-1-methylthio-2-nitroethylene；N,N-dimethyl-1-methylsulfanyl-2-nitroethenamine
• CAS: 42506-12-7
• 化学式: C₅H₁₀N₂O₂S
• 分子量: 162.213
• InChiKey: HUDRYGJMGVJMCD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  74.4
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  Dimethyl-((E)-1-methylsulfanyl-2-nitro-vinyl)-amine 在 汞 水 作用下， 以 乙腈 为溶剂， 生成 N,N-二甲基-2-硝基-乙酰胺
  参考文献：
  名称：

  硝基烯酮-s，n-乙缩醛作为硝基乙酰胺和难以捉摸的硝基硫代乙酰胺的前体

  摘要：

  1-氨基-1-甲硫基-2-硝基乙烯（2）可以通过Hg 2+催化水解以高产率转化为硝基乙酰胺（3），而在乙醇-乙酸中通过Na 2 S转化为硝基硫代乙酰胺（4）。

  DOI：

  10.1016/s0040-4039(00)88798-5
• 作为产物：
  描述：

  二甲胺 、 1,1-双(甲硫基)-2-亚硝基乙烯 以 乙腈 为溶剂， 生成 Dimethyl-((E)-1-methylsulfanyl-2-nitro-vinyl)-amine
  参考文献：
  名称：

  硝基烯酮-s，n-乙缩醛作为硝基乙酰胺和难以捉摸的硝基硫代乙酰胺的前体

  摘要：

  1-氨基-1-甲硫基-2-硝基乙烯（2）可以通过Hg 2+催化水解以高产率转化为硝基乙酰胺（3），而在乙醇-乙酸中通过Na 2 S转化为硝基硫代乙酰胺（4）。

  DOI：

  10.1016/s0040-4039(00)88798-5

文献信息

• Alpha-unsaturated amine pyridine compounds
  申请人：Takeda Chemical Industries, Ltd.

  公开号：US05175301A1

  公开（公告）日：1992-12-29

  .alpha.-Unsaturated amines of the formula: ##STR1## wherein X.sup.1 and X.sup.2 are such that one is an electron-attracting group with the other being a hydrogen atom or an electron-attracting group; R.sup.1 is a group attached through a nitrogen atom; R.sup.2 is a hydrogen atom or a group attached through a carbon, nitrogen or oxygen atom; n is an integer equal to 0, 1 or 2; A is a heterocyclic group or a cyclic hydrocarbon group, and salts thereof and their agrochemical use as insecticidal and/or miticidal agents are described.

  本文描述了化学式为：##STR1##的.alpha.-不饱和胺，其中X.sup.1和X.sup.2是电子吸引基团，其中一个是氢原子或电子吸引基团，R.sup.1是通过氮原子连接的基团，R.sup.2是氢原子或通过碳、氮或氧原子连接的基团，n是等于0、1或2的整数，A是杂环基团或环烃基团，以及它们的盐和它们作为杀虫和/或杀螨剂的农药用途。
• Halogen substituted 5-thiazole methane amine compounds
  申请人：Takeda Chemical Industries, Ltd.

  公开号：US05214152A1

  公开（公告）日：1993-05-25

  .alpha.-Unsaturated amines of the formula: ##STR1## wherein X.sup.1 and X.sup.2 are such that one is an electron-attracting group with the other being a hydrogen atom or an electron-attracting group; R.sup.1 is a group attached through a nitrogen atom; R.sup.2 is a hydrogen atom or a group attached through a carbon, nitrogen or oxygen atom; n is an integer equal to 0, 1 or 2; A is a heterocyclic group or a cyclic hydrocarbon group, and salts thereof and their agrochemical use as insecticidal and/or miticidal agents are described.

  本发明涉及一种以下式子的.alpha.-不饱和胺：##STR1## 其中X.sup.1和X.sup.2是这样的，其中一个是吸电子基团，另一个是氢原子或吸电子基团；R.sup.1是通过氮原子连接的基团；R.sup.2是氢原子或通过碳、氮或氧原子连接的基团；n是等于0、1或2的整数；A是杂环基团或环烃基团，以及它们的盐和作为杀虫和/或杀螨剂的农药用途。
• Preparation of substituted ethenes
  申请人：Fine Organics Limited

  公开号：US05371247A1

  公开（公告）日：1994-12-06

  A potassium salt useful in the production of certain N-substituted alkyl or arylalkyl thionitroethenamines is produced by the reaction of the dipotassium salt of a 2-nitrodithio aliphatic acid such as 2-nitrodithio acetic acid with branched chain primary alkylamines, secondary alkylamines, arylalkylamines or heterocyclic alkylamines such as dimethylamine, pinacolylamine, benzylamine or piperonylamine, thereby converting one only of the KS-groups to an alkylamine group. The resulting monopotassium salt may be alkylated or arylalkylated to produce an N-substituted alkyl or arylalkyl thionitroethenamine. This compound may be reacted with a suitable amine to produce compounds containing the pharmaceutically active grouping --NHC(.dbd.CHNO.sub.2)NHX, wherein X represents an alkyl, arylalkyl or heterocyclic alkyl group.

  通过将2-硝基二硫代醋酸的二钾盐与支链初级烷胺、次级烷胺、芳基烷胺或杂环烷胺（例如二甲胺、皮纳科利胺、苄胺或吡哆酰胺）反应，可以生产一种在生产某些N-取代烷基或芳基烷基硫代亚硝基乙烯胺时有用的钾盐，从而将KS基团之一转化为烷基胺基团。所得的单钾盐可以烷基化或芳基烷基化，以产生N-取代烷基或芳基烷基硫代亚硝基乙烯胺。此化合物可以与适当的胺反应，以产生含有药用活性基团--NHC(.dbd.CHNO.sub.2)NHX的化合物，其中X代表烷基、芳基烷基或杂环烷基。
• &agr;-unsaturated amines, their production and use
  申请人：Takeda Chemical Industries, Ltd.

  公开号：US06407248B1

  公开（公告）日：2002-06-18

  &agr;-Unsaturated amines of the formula: wherein X1 and X2 are such that one is an electron-attracting group with the other being a hydrogen atom or an electron-attracting group; R1 is a group attached through a nitrogen atom; R2 is a hydrogen atom or a group attached through a carbon, nitrogen or oxygen atom; n is an integer equal to 0, 1 or 2; A is a heterocyclic group or a cyclic hydrocarbon group, and salts thereof and their agrochemical use as insecticidal and/or miticidal agents are described.

  本发明涉及一种&agr;-不饱和胺，其化学式为：其中X1和X2是这样的，一个是电子吸引基团，另一个是氢原子或电子吸引基团；R1是通过氮原子连接的基团；R2是氢原子或通过碳、氮或氧原子连接的基团；n是等于0、1或2的整数；A是杂环基团或环烃基团，以及它们的盐和作为杀虫剂和/或螨虫剂的农药用途的描述。
• .alpha.-unsaturated amines, their production and use
  申请人：Takeda Chemical Industries, Ltd.

  公开号：US05849768A1

  公开（公告）日：1998-12-15

  .alpha.-Unsaturated amines of the formula: ##STR1## wherein X.sup.1 and X.sup.2 are such that one is an electron-attracting group with the other being a hydrogen atom or an electron-attracting group; R.sup.1 is a group attached through a nitrogen atom; R.sup.2 is a hydrogen atom or a group attached through a carbon, nitrogen or oxygen atom; n is an integer equal to 0, 1 or 2; A is a heterocyclic group or a cyclic hydrocarbon group, and salts thereof and their agrochemical use as insecticidal and/or miticidal agents are described.

  本文描述了公式为：##STR1## 的.alpha.-不饱和胺，其中X.sup.1和X.sup.2是电子吸引基团和氢原子或电子吸引基团，R.sup.1是通过氮原子连接的基团，R.sup.2是氢原子或通过碳、氮或氧原子连接的基团，n是等于0、1或2的整数，A是杂环基团或环烃基团，以及它们的盐和作为杀虫剂和/或螨虫剂的农药应用。