4-(戊基氨基)苯甲酸 | 75681-60-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 4-(戊基氨基)苯甲酸
• 英文名称: 4-Pentylamino-benzoesaeure
• 英文别名: 4-(pentylamino)benzoic acid
• CAS: 75681-60-6
• 化学式: C₁₂H₁₇NO₂
• 分子量: 207.272
• InChiKey: PEIGTVJQKKVZSK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  49.3
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  4-(戊基氨基)苯甲酸 、 氰基联苯酚 在 氯化亚砜 作用下， 生成 4-Pentylamino-benzoic acid 4'-cyano-biphenyl-4-yl ester
  参考文献：
  名称：

  Gureviciene, J.-J.; Adomenas, P., Molecular Crystals and Liquid Crystals (1969-1991), 1984, vol. 103, p. 177 - 180

  摘要：

  DOI：
• 作为产物：
  描述：

  4-pentylamino-benzoic acid ethyl ester 在 sodium hydroxide 作用下， 生成 4-(戊基氨基)苯甲酸
  参考文献：
  名称：

  Sulfur-Containing Amines. VIII.¹ Local Anesthetics. III

  摘要：

  DOI：

  10.1021/ja01178a028

文献信息

• PHOTOPROTECTIVE COMPOSITIONS COMPRISING PHOTOSENSITIVE 1,3,5-TRIAZINE COMPOUNDS, DIBENZOYLMETHANE COMPOUNDS AND SILICEOUS S-TRIAZINES SUBSTITUTED WITH TWO AMINOBENZOATE OR AMINOBENZAMIDE GROUPS
  申请人：L'OREAL

  公开号：US20170135933A1

  公开（公告）日：2017-05-18

  UV-photoprotective, topically applicable cosmetic/dermatological compositions contain: (a) at least one dibenzoylmethane compound, (b) at least one 1,3,5-triazine compound that is photosensitive in the presence of a dibenzoylmethane compound, and (c) at least one siliceous s-triazine compound substituted with two aminobenzoate or aminobenzamide groups, or a tautomeric form thereof, the 1,3,5-triazine compounds being improvedly photostable in such compositions.

  UV-光保护，可局部应用的化妆品/皮肤科组合物包含： (a) 至少一种二苯甲酮化合物， (b) 至少一种1,3,5-三嗪化合物，在二苯甲酮化合物存在时对光敏感，以及 (c) 至少一种含有两个氨基苯甲酸酯或氨基苯酰胺基团的硅质s-三嗪化合物，或其互变异构体，这些1,3,5-三嗪化合物在这种组合物中具有改进的光稳定性。
• Photoprotective compositions comprising photosensitive 1,3,5-triazine compounds, dibenzoylmethane compounds and siliceous s-triazines substituted with two aminobenzoate or aminobenzamide groups
  申请人：Candau Didier

  公开号：US20100003207A1

  公开（公告）日：2010-01-07

  UV-photoprotective, topically applicable cosmetic/dermatological compositions contain: (a) at least one dibenzoylmethane compound, (b) at least one 1,3,5-triazine compound that is photosensitive in the presence of a dibenzoylmethane compound, and (c) at least one siliceous s-triazine compound substituted with two aminobenzoate or aminobenzamide groups, or a tautomeric form thereof, the 1,3,5-triazine compounds being improvedly photostable in such compositions.

  紫外线光保护、可局部应用的化妆品/皮肤科学组合物包含：(a) 至少一种二苯甲酮类化合物，(b) 至少一种在存在二苯甲酮类化合物时对光敏感的1,3,5-三嗪类化合物，以及(c) 至少一种含有两个氨基苯甲酸酯或氨基苯酰胺基团或其互变异构体的含硅三嗪化合物，这些1,3,5-三嗪类化合物在这种组合物中具有改进的光稳定性。
• Novel sunscreen agents, sunscreen compositions and methods for
  申请人：The Procter & Gamble Company

  公开号：US04999186A1

  公开（公告）日：1991-03-12

  The present invention relates to novel sunscreen agents which have the ability to absorb both UVA and UVB wavelength radiation. The sunscreen agents comprise a specific type of UVA-absorbing chromophore covalently bonded to a specific type of UVB-absorbing chromophore. The chromophore moieties are covalently bonded together such that the electron systems of these moieties are not directly coupled. The present invention further relates to sunscreen compositions containing the hereinbefore described type of sunscreen agents. Furthermore, the present invention relates to methods for protecting the skin of humans or lower animals from the effects of UVA and UVB wavelength radiation. This method comprises topically applying to the skin an effective coating of a sunscreen composition of the present invention.

  本发明涉及一种新型防晒剂，具有吸收UVA和UVB波长辐射的能力。防晒剂包括一种特定类型的吸收UVA的色团和一种特定类型的吸收UVB的色团共价结合在一起。这些色团基团通过共价键结合在一起，使得这些基团的电子系统没有直接耦合。本发明还涉及含有上述类型防晒剂的防晒组合物。此外，本发明涉及一种方法，用于保护人类或低等动物的皮肤免受UVA和UVB波长辐射的影响。该方法包括局部涂抹本发明的防晒组合物，形成有效的涂层。
• UV-photoprotective compositions comprising diebenzoylmethane screening agents and silicon-containing s-triazine compounds substituted with two aminobenzoate or aminobenzamide groups
  申请人：Richard Herve

  公开号：US20080145324A1

  公开（公告）日：2008-06-19

  UV-photostable, topically applicable cosmetic/dermatological compositions contain at least one dibenzoylmethane UV-sunscreen compound and at least one photostabilizing silicon-containing s-triazine compound substituted with two aminobenzoate or aminobenzamide groups.

  具有紫外线光稳定性的局部适用美容/皮肤学组合物包含至少一种二苯甲酮紫外线防晒剂化合物和至少一种被两个氨基苯甲酸酯或氨基苯酰胺基团取代的光稳定硅含有s-三嗪化合物。
• Photoprotective cosmetic compositions comprising silicon-containing s-triazine compounds substituted with two aminobenzoate or aminobenzamide groups and non-silicon-containing lipophilic triazine compound UV-screening agents
  申请人：Candau Didier

  公开号：US20080138303A1

  公开（公告）日：2008-06-12

  UV-photoprotective, topically applicable cosmetic/dermatological compositions contain: (a) at least one silicon-containing s-triazine substituted with two aminobenzoate or aminobenzamide groups of specific formula (I), and (b) at least one non-silicon-containing lipophilic 1,3,5-triazine compound UV-screening agent, such compositions having improved photoprotective effectiveness in the UV-B range and the 1,3,5-triazine compound(s) being improvedly soluble therein.

  具有紫外线光保护作用的，可局部应用于化妆品/皮肤科学组合物包含以下成分：（a）至少一种含硅的S-三嗪基，其被两个氨基苯甲酸酯或氨基苯甲酰基取代，具有特定的化学式（I），以及（b）至少一种不含硅的亲脂性1,3,5-三嗪化合物紫外线筛选剂，这种组合物在UV-B范围内具有改善的光保护效果，1,3,5-三嗪化合物具有改善的溶解度。