2-乙烯基-4-甲基-1,3-二氧戊环 | 2421-07-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氧戊环
• 中文名称: 2-乙烯基-4-甲基-1,3-二氧戊环
• 中文别名: 盐(1:?)硼酸(H3BO3),铵
• 英文名称: 4-Methyl-2-vinyl-1,3-dioxolan
• 英文别名: 2-Vinyl-4-methyl-1,3-dioxolan；4-Methyl-2-vinyl-1,3-dioxolane；2-ethenyl-4-methyl-1,3-dioxolane
• CAS: 2421-07-0
• 化学式: C₆H₁₀O₂
• 分子量: 114.144
• InChiKey: BGIDUFCVXOXJNO-UHFFFAOYSA-N

物化性质

• 沸点：
  35 °C(Press: 8 Torr)
• 密度：
  0.9063 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  8
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2932999099

反应信息

• 作为反应物：
  描述：

  2-乙烯基-4-甲基-1,3-二氧戊环 在 tris(triphenylphosphine)ruthenium(II) chloride 、 对甲苯磺酸 作用下， 以 四氢呋喃 、 甲苯 为溶剂， 反应 5.0h， 生成 3-((2-ethyl-4-methyl-1,3-dioxolan-2-yl)oxy)propan-1-ol
  参考文献：
  名称：

  用侧基侧酯容易合成酸不稳定的聚合物

  摘要：

  这项工作提出了一种简便的方法，用于制备带有侧链环酯的酸不稳定和生物相容性聚合物，该方法基于环状烯酮缩醛（CKA）与羟基之间的有效且温和的反应。分别从CKA制备了三个CKA，2-亚乙基-1,3-二氧戊环（EDO），2-亚乙基-1,3-二氧戊环（EDL）和2-亚乙基-4-甲基-1,3-二氧戊环（EMD）。通过双键的催化异构化得到相应的环状乙烯基缩醛。使用痕量对甲苯磺酸作为催化剂，检查了CKA与不同醇和二醇的反应。对于一羟基醇，通过与乙醇简单地向CKA加成羟基，即可形成环状原酸酯，与异氰酸酯相比，其反应活性要大得多。-丙醇。当使用1,2-或1,3-二醇与CKA反应时，除了简单的加成产物外，我们还观察到了异构化的环状原酸酯。然后用CKA改性生物相容性多元醇，即聚丙烯酸2-羟乙酯（PHEA）和聚乙烯醇（PVA），并且可以通过改变进料比轻松调节侧链原酸酯的取代度。小分子原酸酯和经CKA改性的聚合物均显

  DOI：

  10.1021/bm201410c
• 作为产物：
  描述：

  丙烯醛 生成 2-乙烯基-4-甲基-1,3-二氧戊环
  参考文献：
  名称：

  NANDZE, KATSUMI;VATANABEH, TOSINOSUKEH

  摘要：

  DOI：

文献信息

• SULFUR-CONTAINING SILANE COUPLING AGENTS
  申请人：——

  公开号：US20020002220A1

  公开（公告）日：2002-01-03

  A method is provided for preparing sulfur-containing silane coupling agents by reacting an alkoxysilane acetal with a sulfurating agent. The sulfur-containing silane coupling agents so prepared include certain novel mercapto silanes, and are useful in providing rubber tires with improved properties.

  提供了一种方法，通过将烷氧基硅醇缩醛与硫化剂反应来制备含硫硅烷偶联剂。由此制备的含硫硅烷偶联剂包括某些新型巯基硅烷，并可用于提供具有改善性能的橡胶轮胎。
• Process of hydroformylating cyclic acrolein acetals
  申请人：E.I. DU PONT DE NEMOURS AND COMPANY

  公开号：EP0003753A1

  公开（公告）日：1979-09-05

  A process for hydroformylating a cyclic acrolein acetal to form the corresponding cyclic acrolein acetal aldehyde, said process comprising conducting said hydroformylation in the presence of carbon monoxide, hydrogen, rhodium complex catalyst and 1-3%of excess triphenyl phosphite ligand based on the acetal at a pressure of carbon monoxide of from 5-20 psia and a pressure of hydrogen of from 10- 400 psia maintained with a gas having a H2:CO ratio of from 1:1-20:1 and a temperature of from 100-115°C, the rhodium content of said catalyst being 1-50 ppm of rhodium based on the acetal.

  一种使环丙烯醛缩醛加氢甲酰化以形成相应的环丙烯醛缩醛醛的工艺，所述工艺包括在一氧化碳、氢气、铑络合催化剂和以缩醛为基质的1-3%过量亚磷酸三苯酯配体存在下，在一氧化碳压力为5-20psia和氢气压力为10-400psia的条件下进行所述加氢甲酰化，维持气体的H2：所述催化剂的铑含量为 1-50 ppm（以缩醛为基准）。
• Shell-Sheddable, pH-Sensitive Supramolecular Nanoparticles Based on Ortho Ester-Modified Cyclodextrin and Adamantyl PEG
  作者：Ran Ji、Jing Cheng、Ting Yang、Cheng−Cheng Song、Lei Li、Fu-Sheng Du、Zi-Chen Li

  DOI：10.1021/bm500711c

  日期：2014.10.13

  We report a new type of pH-sensitive supramolecular aggregates which possess a programmable character of sequential dePEGylation and degradation. As a platform of designing and building multifunctional supramolecular nanoparticles, a family of 6-OH ortho ester-modified beta-cyclodextrin (beta-CD) derivatives have been synthesized via the facile reaction between beta-CD and cyclic ketene acetals with different alkyl lengths. These asymmetric acid-labile beta-CD derivatives formed amphiphilic supramolecules with adamantane-modified PEG through host-guest interaction in polar solvents such as ethanol. The supramolecules can self-assemble in water to form acid-labile supramolecular aggregates. The results of TEM and light scattering measurements demonstrate that the size and morphology of the aggregates are influenced by the alkyl or PEG length and the host-guest feed ratio. By carefully balancing the alkyl and PEG lengths and adjusting the host-guest ratio, well-dispersed vesicles (50-100 nm) or sphere-like nanoparticles (200-500 nm) were obtained. Zeta potential measurements reveal that these supramolecular aggregates are capable of being surface-functionalized via dynamic host-guest interaction. The supramolecular aggregates were stable at pH 8.4 for at least 12 h as proven by the (1)H NMR and LLS measurements. However, rapid dePEGylation occurred at pH 7.4 due to the hydrolysis of the ortho ester linkages locating at the interface, which resulted in aggregation of the dePEGylated hydrophobic inner cores. Upon further decreasing the pH to 6.4, the hydrophobic cores were further degraded due to the acid-accelerated hydrolysis of the ortho esters. The incubation stability of the acid-labile supramolecular aggregates in neutral buffer could be improved by incorporating hydrophobic poly(e-caprolactone) into the core of the aggregates.
• Autoxidation of 2-Alkenyldioxolanes and 2-Alkenyl-1,3-dioxanes
  作者：C. K. Ikeda、R. A. Braun、B. E. Sorenson

  DOI：10.1021/jo01025a007

  日期：1964.2
• Reaction of diazomethane with some .alpha., .beta.-unsaturated acetals and aldehydes
  作者：John M. Stewart、Connie Carlisle、Kenneth Kem、Gregory Lee

  DOI：10.1021/jo00831a079

  日期：1970.6