乙基1,3-二氧戊环-4-羧酸酯 | 33329-93-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氧戊环
• 中文名称: 乙基1,3-二氧戊环-4-羧酸酯
• 英文名称: Ethyl 1,3-dioxolane-4-carboxylate
• CAS: 33329-93-0
• 化学式: C₆H₁₀O₄
• 分子量: 146.14
• InChiKey: YCGUYDQHWPSYTL-UHFFFAOYSA-N

物化性质

• 沸点：
  170.6±25.0 °C(Predicted)
• 密度：
  1.169±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  10
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  44.8
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• SUBSTITUTED CYCLOALKENE DERIVATIVE
  申请人：Kimura Tomio

  公开号：US20090233952A1

  公开（公告）日：2009-09-17

  [Object] To provide a substituted cycloalkene derivative having an action to suppress intracellular signal transduction or cell activation induced by endotoxin and to suppress cell responses due to the intracellular signal transduction and cell activation such as an excess generation of inflammatory mediators such as TNF-α, pharmacologically acceptable salts therefor, a medicament containing them as an active ingredient, a preparation method therefor, and a medicament containing the aforementioned substituted cycloalkene derivative as an active ingredient which is superior in prophylaxis and/or treatment of diseases such as sepsis (septic shock, disseminated intravascular coagulation, multiple organ failure and the like), that are associated with intracellular signal transduction or cell activation induced by endotoxin and to cell responses to the intracellular signal transduction and cell activation. [Solution] A compound represented by the general formula (I): wherein X and Y represent a group in which X and Y together with a carbon atom to which they are bound form ring A (the ring is 3- to 7-membered heterocyclyl ring or 3- to 7-membered cycloalkyl ring), each represents a hydrogen atom, or X and Y together represent a substituent of ring B. l and m, independently from each other, represent an integer of 0 to 3, and l+m is 1 to 3. R 1 is an aliphatic hydrocarbon group and the like which may be substituted with a group selected from Substituent group β and Substituent group γ. n represents an integer of 0 to 3. R 2 is a C 1 -C 6 alkyl group and the like which may be substituted with a group selected from a hydrogen atom and Substituent group β. R 3 is a phenyl group, 5- to 6-membered heteroaryl group and the like which may be substituted with a group selected from Substituent group ε. R 5 is a C 1 -C 6 alkyl group and the like which may be substituted with a group selected from a hydrogen atom and Substituent group β. Provided that in the case where R 3 is a phenyl group which may be substituted with a group selected from Substituent group ε, X and Y represent a group in which X and Y together with a carbon atom to which they are bound form ring A, or X and Y together represent a substituent of ring B.

  [目的] 提供一种替代环烯烃衍生物，具有抑制内毒素诱导的细胞内信号传导或细胞活化并抑制细胞对细胞内信号传导和细胞活化的反应，例如过量生成TNF-α等炎症介质，其药理学上可接受的盐，包含其作为活性成分的药物，其制备方法以及含有上述替代环烯烃衍生物作为活性成分的药物，其在预防和/或治疗与内毒素诱导的细胞内信号传导或细胞活化以及对细胞内信号传导和细胞活化的反应有关的疾病，例如败血症（败血性休克，弥漫性血管内凝血，多器官衰竭等）方面具有优越性。 [解决方案] 一种由通式（I）表示的化合物：其中，X和Y表示与它们结合的碳原子形成环A（环为3-至7成员的杂环或3-至7成员的环烷基环）的基团，每个表示氢原子，或X和Y一起表示环B的取代基。l和m，独立地，表示0至3的整数，且l+m为1至3。R1是脂肪烃基等，可以被从取代基组β和取代基组γ中选择的基团取代。n表示0至3的整数。R2是C1-C6烷基等，可以被从氢原子和取代基组β中选择的基团取代。R3是苯基，5-至6成员的杂环基等，可以被从取代基组ε中选择的基团取代。R5是C1-C6烷基等，可以被从氢原子和取代基组β中选择的基团取代。但在R3是苯基且可以被从取代基组ε中选择的基团取代的情况下，X和Y表示与它们结合的碳原子形成环A的基团，或X和Y一起表示环B的取代基。
• NONAQUEOUS ELECTROLYTE, CAPACITOR DEVICE USING SAME, AND CARBOXYLIC ACID ESTER COMPOUND USED IN SAME
  申请人：UBE Industries, Ltd.

  公开号：EP3086396A1

  公开（公告）日：2016-10-26

  The present invention provides a nonaqueous electrolytic solution capable of improving electrochemical characteristics in the case of using an energy storage device at a high temperature and at a high voltage and further capable of inhibiting the gas generation while maintaining a capacity retention rate after storage at a high temperature and at a high voltage and also provides an energy storage device using the same. Disclosed is a nonaqueous electrolytic solution having an electrolyte salt dissolved in a nonaqueous solvent, the nonaqueous electrolytic solution containing a carboxylic acid ester compound represented by the following general formula (I). In the formula, each of R1 and R2 independently represents a hydrogen atom, a -C(=O)-OR4 group, or the like, and R1 and R2 may be bonded to each other to form a ring structure. R3 represents a hydrogen atom or the like, and n represents an integer of 1 to 3. When n is 1, then L and R4 represent an alkyl group having 1 to 6 carbon atoms or the like; and when n is 2 or 3, then L represents an n-valent connecting group, X represents a -C(=O)- group, an -S(=O)-group, an -S(=O)2- group, an -S(=O)2-R5-S(=O)2- group or a CR6R7 group, R5 represents an alkylene group having 1 to 4 carbon atoms, and each of R6 and R7 represents a hydrogen atom or an alkyl group having 1 to 6 carbon atoms.

  本发明提供了一种非水性电解溶液，该溶液能够改善在高温高压下使用储能装置时的电化学特性，并且能够进一步抑制气体生成，同时在高温高压下储存后保持容量保持率，本发明还提供了使用该溶液的储能装置。本发明公开了一种非水电解溶液，该溶液具有溶解在非水溶剂中的电解质盐，该非水电解溶液含有由以下通式（I）代表的羧酸酯化合物。 式中，R1 和 R2 各自独立地代表氢原子、-C(＝O)-OR4 基团或类似基团，R1 和 R2 可相互键合以形成环状结构。R3 代表氢原子或类似物，n 代表 1 至 3 的整数。当 n 为 1 时，L 和 R4 代表具有 1 至 6 个碳原子的烷基或类似基团；当 n 为 2 或 3 时，L 代表 n 价连接基团，X 代表 -C(=O)- 基团、-S(=O)- 基团、-S(=O)2- 基团、-S(=O)2-R5-S(=O)2- 基团或 CR6R7 基团，R5 代表具有 1 至 4 个碳原子的亚烷基，R6 和 R7 分别代表氢原子或具有 1 至 6 个碳原子的烷基。
• Nonaqueous electrolyte, capacitor device using same, and carboxylic acid ester compound used in same
  申请人：UBE INDUSTRIES, LTD.

  公开号：US10263285B2

  公开（公告）日：2019-04-16

  The present invention provides a nonaqueous electrolytic solution capable of improving electrochemical characteristics in the case of using an energy storage device at a high temperature and at a high voltage and further capable of inhibiting the gas generation while maintaining a capacity retention rate after storage at a high temperature and at a high voltage and also provides an energy storage device using the same. Disclosed is a nonaqueous electrolytic solution having an electrolyte salt dissolved in a nonaqueous solvent, the nonaqueous electrolytic solution containing a carboxylic acid ester compound represented by the following general formula (I). In the formula, each of R1 and R2 independently represents a hydrogen atom, a —C(═O)—OR4 group, or the like, and R1 and R2 may be bonded to each other to form a ring structure. R3 represents a hydrogen atom or the like, and n represents an integer of 1 to 3. When n is 1, then L and R4 represent an alkyl group having 1 to 6 carbon atoms or the like; and when n is 2 or 3, then L represents an n-valent connecting group, X represents a —C(═O)— group, an —S(═O)— group, an —S(═O)2— group, an —S(═O)2—R5—S(═O)2— group or a CR6R7 group, R5 represents an alkylene group having 1 to 4 carbon atoms, and each of R6 and R7 represents a hydrogen atom or an alkyl group having 1 to 6 carbon atoms.

  本发明提供了一种非水性电解溶液，该溶液能够改善在高温高压下使用储能装置时的电化学特性，并且能够进一步抑制气体生成，同时在高温高压下储存后保持容量保持率，本发明还提供了使用该溶液的储能装置。本发明公开了一种非水电解溶液，该溶液具有溶解在非水溶剂中的电解质盐，该非水电解溶液含有由以下通式（I）代表的羧酸酯化合物。 式中，R1 和 R2 各自独立地代表氢原子、-C(═O)-OR4 基团或类似基团，R1 和 R2 可相互键合以形成环状结构。R3 代表氢原子或类似物，n 代表 1 至 3 的整数。当 n 为 1 时，L 和 R4 代表具有 1 至 6 个碳原子的烷基或类似基团；当 n 为 2 或 3 时，L 代表 n 价连接基团，X 代表-C(═O)-基团、-S(═O)-基团、-S(═O)2-基团、-S(═O)2-R5-S(═O)2-基团或 CR6R7 基团，R5 代表具有 1 至 4 个碳原子的亚烷基，R6 和 R7 分别代表氢原子或具有 1 至 6 个碳原子的烷基。
• NONAQUEOUS ELECTROLYTE WITH CARBOXYLIC ACID ESTER COMPOUND AND ENERGY STORAGE DEVICE USING SAME
  申请人：UBE Industries, Ltd.

  公开号：EP3086396B1

  公开（公告）日：2019-06-05
• US7935835B2
  申请人：——

  公开号：US7935835B2

  公开（公告）日：2011-05-03