Methanesulfonic acid (4S,5S)-5-methanesulfonyloxymethyl-2-(2-thiophen-3-yl-ethyl)-[1,3]dioxolan-4-ylmethyl ester | 334899-51-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: Methanesulfonic acid (4S,5S)-5-methanesulfonyloxymethyl-2-(2-thiophen-3-yl-ethyl)-[1,3]dioxolan-4-ylmethyl ester
• 英文别名: [(4S,5S)-5-(methylsulfonyloxymethyl)-2-(2-thiophen-3-ylethyl)-1,3-dioxolan-4-yl]methyl methanesulfonate
• CAS: 334899-51-3
• 化学式: C₁₃H₂₀O₈S₃
• 分子量: 400.495
• InChiKey: JIRCTHBPYSXQEZ-RYUDHWBXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  24
• 可旋转键数：
  9
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.69
• 拓扑面积：
  150
• 氢给体数：
  0
• 氢受体数：
  9

反应信息

• 作为反应物：
  描述：

  lithium boranyl-diphenyl-phosphanide 、 Methanesulfonic acid (4S,5S)-5-methanesulfonyloxymethyl-2-(2-thiophen-3-yl-ethyl)-[1,3]dioxolan-4-ylmethyl ester 以 四氢呋喃 为溶剂， 反应 12.0h， 以47%的产率得到
  参考文献：
  名称：

  Chiral auxiliaries onto conducting polymers

  摘要：

  The synthesis of new chiral auxiliaries was performed onto conducting polythiophene. The electrochemical behaviour of such a matrix was investigated and one of them present a noticeable stability when an adequate spacer is introduced between the redox centre and the chiral unit. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(00)02144-4
• 作为产物：
  描述：

  3-(3-Thienyl)propanal 在 lithium aluminium tetrahydride 、 氢气 、 三乙胺 作用下， 以 乙醚 、 二氯甲烷 、 苯 为溶剂， 生成 Methanesulfonic acid (4S,5S)-5-methanesulfonyloxymethyl-2-(2-thiophen-3-yl-ethyl)-[1,3]dioxolan-4-ylmethyl ester
  参考文献：
  名称：

  Chiral auxiliaries onto conducting polymers

  摘要：

  The synthesis of new chiral auxiliaries was performed onto conducting polythiophene. The electrochemical behaviour of such a matrix was investigated and one of them present a noticeable stability when an adequate spacer is introduced between the redox centre and the chiral unit. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(00)02144-4

文献信息

• Chiral auxiliaries onto conducting polymers
  作者：Pascal Pellon、Elisabeth Deltel、Jean-François Pilard

  DOI：10.1016/s0040-4039(00)02144-4

  日期：2001.1

  The synthesis of new chiral auxiliaries was performed onto conducting polythiophene. The electrochemical behaviour of such a matrix was investigated and one of them present a noticeable stability when an adequate spacer is introduced between the redox centre and the chiral unit. (C) 2001 Elsevier Science Ltd. All rights reserved.