4-丁基磺酰基苯甲酸 | 100059-51-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 4-丁基磺酰基苯甲酸
• 英文名称: 4-Butylsulfonyl-benzoesaeure
• 英文别名: 4-(butane-1-sulfonyl)-benzoic acid；4-(Butan-1-sulfonyl)-benzoesaeure；Benzoic acid, 4-(butylsulfonyl)-；4-butylsulfonylbenzoic acid
• CAS: 100059-51-6
• 化学式: C₁₁H₁₄O₄S
• mdl: MFCD09935862
• 分子量: 242.296
• InChiKey: ZBKOZGCANJUKEY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.363
• 拓扑面积：
  79.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  4-丁基磺酰基苯甲酸 在 氯化亚砜 作用下， 生成 4-(butane-1-sulfonyl)-benzaldehyde
  参考文献：
  名称：

  DE934590

  摘要：

  公开号：
• 作为产物：
  描述：

  p-(n-butylmercapto)-benzaldehyde 在 双氧水 、 溶剂黄146 作用下， 生成 4-丁基磺酰基苯甲酸
  参考文献：
  名称：

  Primary leiomyosarcoma of the heart subsequent to double carcinomas of the thyroid and lung

  摘要：

  A 63-year-old woman underwent surgical operations for left lower lung cancer and for thyroid cancer. Nine months later, a third cancer developed in her heart and this tumor was removed by open heart surgery. A pathologic study revealed that the tumor was primary leiomyosarcoma of the heart and thus independent from the previous lung and thyroid carcinomas. This case was regarded as a triple carcinoma including a primary leiomyosarcoma arising from the left atrium. Reports in the literature on primary malignant tumors of the heart are reviewed briefly.

  DOI：

  10.1007/pl00007262

文献信息

• A convenient method for the preparation of (alkylsulfonyl)benzoic acids
  作者：Richard W. Brown

  DOI：10.1021/jo00016a032

  日期：1991.8
• DE934590
  申请人：——

  公开号：——

  公开（公告）日：——
• Primary leiomyosarcoma of the heart subsequent to double carcinomas of the thyroid and lung
  作者：M. Fukuoka、Makoto Hagiwara、Shinya Shimoshige、Akifumi Hirata、Takeo Adachi、Hiroaki Komura、Tetsuro Shoji、Tsuyoshi Kikuiri、Katsuya Ikeda、Nozomu Kimura、Yasunori Fujisawa

  DOI：10.1007/pl00007262

  日期：2000.3

  A 63-year-old woman underwent surgical operations for left lower lung cancer and for thyroid cancer. Nine months later, a third cancer developed in her heart and this tumor was removed by open heart surgery. A pathologic study revealed that the tumor was primary leiomyosarcoma of the heart and thus independent from the previous lung and thyroid carcinomas. This case was regarded as a triple carcinoma including a primary leiomyosarcoma arising from the left atrium. Reports in the literature on primary malignant tumors of the heart are reviewed briefly.