Present invention represents process for the preparation of HMG-CoA reductase inhibitors, in particular rosuvastatin calcium introducing L-malic acid as the source of chirality for the side chain.
[EN] PROCESS FOR THE SYNTHESIS OF ROSUVASTATIN CALCIUM<br/>[FR] PROCESSUS DESTINE A LA SYNTHESE DE CALCIUM ROSUVASTATINE
申请人:LEK PHARMACEUTICALS
公开号:WO2007017117A1
公开(公告)日:2007-02-15
[EN] Present invention represents process for the preparation of HMG-CoA reductsase inhibitors, in particular rosuvastatin calcium introducing L-malic acid as the source of chirality for the side chain. [FR] La présente invention concerne un processus destiné à la préparation des inhibiteurs de HMG-CoA réductase et notamment du calcium rosuvastatine utilisant l'acide L-malique en tant que source de chiralité pour la branche latérale.