[(4-Octoxyphenyl)methylideneamino]urea

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: [(4-Octoxyphenyl)methylideneamino]urea
• 化学式: C₁₆H₂₅N₃O₂
• 分子量: 291.393
• InChiKey: BHSMIKXYUKXWNN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  21
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  76.7
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  [(4-Octoxyphenyl)methylideneamino]urea 在 chloroamine-T 作用下， 以 四氢呋喃 为溶剂， 生成 5-(4-Octoxyphenyl)-1,3,4-oxadiazol-2-amine
  参考文献：
  名称：

  Synthesis and Characterization of Mesogenic 1,3,4-Oxadiazole Derivatives

  摘要：

  A synthesis of homologous series of mesogenic 2-amino-5-alkkloxyphenyl-1,3,4-oxadiazoles were prepared by the oxidative cyclisation of alkyloxybenzaldehyde semicarbozones (4) using chloramines-T (CAT) as osidate via intramolecular cycloaddition reaction. The reaction proceeds in better yield (75-85%) giving the product as solid with low melting points. The optical texture studies have been carried out using Leitz polarizing microscope to identify the liquid crystalline phases at different temperatures and it is found that the synthesized compounds exhibit nematic (N), smectic C (Sm C), smectic I (Sm I) and smectic G (Sm G) phases, sequentially at different temperatures.

  DOI：

  10.1080/15421400903054550
• 作为产物：
  描述：

  1-溴辛烷 在 四丁基溴化铵 、 sodium acetate 、 potassium hydroxide 作用下， 以 四氢呋喃 、 乙醇 为溶剂， 生成 [(4-Octoxyphenyl)methylideneamino]urea
  参考文献：
  名称：

  Synthesis and Characterization of Mesogenic 1,3,4-Oxadiazole Derivatives

  摘要：

  A synthesis of homologous series of mesogenic 2-amino-5-alkkloxyphenyl-1,3,4-oxadiazoles were prepared by the oxidative cyclisation of alkyloxybenzaldehyde semicarbozones (4) using chloramines-T (CAT) as osidate via intramolecular cycloaddition reaction. The reaction proceeds in better yield (75-85%) giving the product as solid with low melting points. The optical texture studies have been carried out using Leitz polarizing microscope to identify the liquid crystalline phases at different temperatures and it is found that the synthesized compounds exhibit nematic (N), smectic C (Sm C), smectic I (Sm I) and smectic G (Sm G) phases, sequentially at different temperatures.

  DOI：

  10.1080/15421400903054550

文献信息

• Chudgar, N. K.; Shah, S. N.; Vora, R. A., Molecular Crystals and Liquid Crystals (1969-1991), 1991, vol. 209, p. 237 - 242
  作者：Chudgar, N. K.、Shah, S. N.、Vora, R. A.

  DOI：——

  日期：——
• Synthesis and Characterization of Mesogenic 1,3,4-Oxadiazole Derivatives
  作者：J. Mahadeva、K. B. Umesha、K. M. L. Rai、Nagappa

  DOI：10.1080/15421400903054550

  日期：2009.9.3

  A synthesis of homologous series of mesogenic 2-amino-5-alkkloxyphenyl-1,3,4-oxadiazoles were prepared by the oxidative cyclisation of alkyloxybenzaldehyde semicarbozones (4) using chloramines-T (CAT) as osidate via intramolecular cycloaddition reaction. The reaction proceeds in better yield (75-85%) giving the product as solid with low melting points. The optical texture studies have been carried out using Leitz polarizing microscope to identify the liquid crystalline phases at different temperatures and it is found that the synthesized compounds exhibit nematic (N), smectic C (Sm C), smectic I (Sm I) and smectic G (Sm G) phases, sequentially at different temperatures.