Indole Amide Derivatives as EP4 Receptor Antagonists
申请人:Boyd Michael
公开号:US20090253756A1
公开(公告)日:2009-10-08
The invention is directed to indole amide derivatives as EP4 receptor antagonists useful for the treatment of EP4 mediated diseases or conditions, such as acute and chronic pain, osteoarthritis, rheumatoid arthritis and cancer. Pharmaceutical compositions and methods of use are also included.
Indole amide derivatives as EP4 receptor antagonists
申请人:Merck Frosst Canada Ltd.
公开号:US07968578B2
公开(公告)日:2011-06-28
The invention is directed to indole amide derivatives as EP4 receptor antagonists useful for the treatment of EP4 mediated diseases or conditions, such as acute and chronic pain, osteoarthritis, rheumatoid arthritis and cancer. Pharmaceutical compositions and methods of use are also included.
INDOLE AMIDE DERIVATIVES AS EP4 RECEPTOR ANTAGONISTS
申请人:Merck Canada Inc.
公开号:EP2013169B1
公开(公告)日:2012-08-22
US7968578B2
申请人:——
公开号:US7968578B2
公开(公告)日:2011-06-28
[EN] INDOLE AMIDE DERIVATIVES AS EP4 RECEPTOR ANTAGONISTS<br/>[FR] DÉRIVÉS D'INDOLAMIDE COMME ANTAGONISTES DU RÉCEPTEUR EP4
申请人:MERCK FROSST CANADA LTD
公开号:WO2007121578A1
公开(公告)日:2007-11-01
[EN] The invention is directed to indole amide derivatives as EP4 receptor antagonists useful for the treatment of EP4 mediated diseases or conditions, such as acute and chronic pain, osteoarthritis, rheumatoid arthritis and cancer. Pharmaceutical compositions and methods of use are also included. [FR] L'invention concerne des dérivés d'indolamide comme antagonistes du récepteur EP4 qui sont utiles pour le traitement de maladies ou affections médiées par l'EP4, par exemple la douleur aiguë et chronique, l'ostéoarthrite, la polyarthrite rhumatoïde et le cancer. L'invention concerne également des compositions pharmaceutiques ainsi que des procédés d'utilisation.