2-(4-氯苯基)-4,5,6,7-四氢异吲哚-1,3-二酮 | 39985-63-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯啉
• 中文名称: 2-(4-氯苯基)-4,5,6,7-四氢异吲哚-1,3-二酮
• 中文别名: 3,4,5,6-四氢-n-(4-氯苯基)邻苯二甲酰亚胺
• 英文名称: chlorophthalim
• 英文别名: Diamate；2-(4-chlorophenyl)-4,5,6,7-tetrahydroisoindole-1,3-dione
• CAS: 39985-63-2
• 化学式: C₁₄H₁₂ClNO₂
• 分子量: 261.708
• InChiKey: MJQBFSWPMMHVSM-UHFFFAOYSA-N

物化性质

• 熔点：
  161-162 °C
• 沸点：
  426.3±28.0 °C(Predicted)
• 密度：
  1.38±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  18
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  37.4
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-(4-氯苯基)-4,5,6,7-四氢异吲哚-1,3-二酮 、 diphosphorus pentasulfide 生成 2-(4-Chlorophenyl)-3-sulfanylidene-2,3,4,5,6,7-hexahydro-1H-isoindol-1-one
  参考文献：
  名称：

  VAKABAYASI, OSAMU;MATSUTANI, KUNI;OTA, XIROKI;UEHXIRA, TEHTSUO;SUDZUKI, S+

  摘要：

  DOI：
• 作为产物：
  描述：

  3,4,5,6-四氢苯酐 、 对氯苯胺 生成 2-(4-氯苯基)-4,5,6,7-四氢异吲哚-1,3-二酮
  参考文献：
  名称：

  Sato, Yukiharu; Kojima, Takashi; Goto, Toshiyuki, Agricultural and Biological Chemistry, 1991, vol. 55, # 11, p. 2677 - 2682

  摘要：

  DOI：

文献信息

• Hydrolysis and Phytotoxic Activity of<i>N</i>-Aryl-3,4,5,6-tetrahydroisophthalimides
  作者：Toshinobu Hoshi、Kazuya Koizumi、Yukiharu Sato、Ko Wakabayashi

  DOI：10.1271/bbb.57.1913

  日期：1993.1

  The phytotoxic action of five N-aryl-3,4,5,6-tetrahydroisophthalimides (isoimides) synthesized was studied using green microalga (Scenedesmus acutus) and sawa millet (Echinochloa utilis). Isoimides had the same phytotoxic activity as that of imides and amide-acids. This fact indicates that isoimides are peroxidizing herbicides too. Their phytotoxic activity against E. utilis and S. acutus was studied in relation to conversion of isoimide to imide and/or amide-acid during the bioassay. The isoimides rapidly changed to the amide-acids and imides in cluture solution. The conversion rate depended on structures of their N-aryl residues. The phytotoxicity of isoimides may be mostly due to the corresponding amide-acids and/or imides. However, because the isoimides, N-4-(4-chlorobenzyloxy)phenyl}-3,4,5,6-tetrahydroisophthalimide, which had a bulky p-substituent on N-aryl ring, slowly converted to the corresponding amide-acid and/or imide, this compound may have the intrinsic phytotoxicity of the isoimide itself.

  合成的五种N-芳基-3,4,5,6-四氢异苯二甲酰亚胺（异亚胺）对绿色微藻（尖头藻）和米草（禾本科植物）进行的植物毒性作用研究表明，异亚胺的植物毒性活动与亚胺和酰胺酸相同。这一事实表明，异亚胺也是过氧化除草剂。其对米草和尖头藻的植物毒性活动与生物测定过程中异亚胺转化为亚胺和/或酰胺酸的关系进行研究。异亚胺在培养溶液中迅速转变为酰胺酸和亚胺。转化速率取决于其N-芳基残基的结构。异亚胺的植物毒性可能主要归因于相应的酰胺酸和/或亚胺。然而，由于N-4-(4-氯苄氧)苯基}-3,4,5,6-四氢异苯二甲酰亚胺在N-芳基环上具有较大取代基，转化为相应酰胺酸和/或亚胺的速率较慢，因此该化合物可能具有异亚胺本身的内在植物毒性。
• Tetrahydrophthalamide derivatives, herbicidal compositions and use
  申请人：Takeda Chemical Industries, Ltd.

  公开号：US04362546A1

  公开（公告）日：1982-12-07

  Tetrahydrophthalamide derivatives of the general formula: ##STR1## wherein X.sub.1 is hydrogen or halogen; X.sub.2 is halogen, alkoxy or substituted benzyloxy; X.sub.3 is hydrogen, alkoxy or alkenyloxy; R and R' are the same or different alkyl, cycloalkyl, alkenyl or phenyl, each of which may be optionally substituted, or may jointly, together with nitrogen atom adjacent to R and R', form aliphatic heterocyclic ring containing one or two nitrogens or nitrogen and oxygen, which have a herbicidal activity against a broad spectrum of monocotyledonous and dicotyledonous weeds.

  通式为：##STR1## 的四氢萘酰胺衍生物，其中X.sub.1为氢或卤素；X.sub.2为卤素，烷氧基或取代苄氧基；X.sub.3为氢，烷氧基或烯基氧基；R和R'是相同或不同的烷基，环烷基，烯基或苯基，每个基都可以选择性地取代，或者可以与靠近R和R'的氮原子一起形成含有一个或两个氮或氮和氧的脂肪杂环环，具有对一系列单子叶和双子叶杂草的除草活性。
• Novel herbicides, usage thereof, novel thienopyrimidine derivatives, intermediates of the same, and process for production thereof
  申请人：Ota Chikako

  公开号：US20070010402A1

  公开（公告）日：2007-01-11

  A herbicide comprising, as an active ingredient, a substituted thienopyrimidine derivative represented by the formula (I): wherein all symbols are defined in the description, a method of using the same, a novel compound useful as the herbicide and a process for producing the same, and an intermediate thereof.

  一种除草剂，其活性成分为由式(I)表示的取代噻唑嘧啶衍生物，其中所有符号在说明中定义，使用该除草剂的方法，作为除草剂有用的新化合物及其生产方法，以及其中间体。
• Cyanbenzofuran derivatives, processes for their preparation and their use in herbicidal compositions; cyanobenzene, benzodioxepine, benzodioxaphosphepine and benzodioxathiepine derivatives
  申请人：FBC LIMITED

  公开号：EP0007719A2

  公开（公告）日：1980-02-06

  The invention provides herbicidally-active 2,3-dihydro-5-cyano-benzofurans of the formula: (wherein: R' and R2 together represent =O or R' represents hydrogen and R2 represents hydrogen, hydroxy, alkoxy, acyloxy, alkoxycarbonyloxy, alkylthiocarbonyloxy, halogen, isothiocyanato, amino, alkylamino, dialkylamino, arylamino, acylamino, alkoxycarbonylamino, alkyhhiocarbonylamino. N-bonded heterocyclyl, cyano or alkylthio; R3 and R4 together represent alkylene or each represent hydrogen or alkyl; and R5, R6 and R7, which may be the same or different, each represent hydrogen, halogen, alkyl, alkoxy, acyl or cyano), processes for their preparation and herbicidal compositions containing them.

  本发明提供了具有除草活性的 2,3-二氢-5-氰基苯并呋喃，其化学式为 其中R'和R2一起代表＝O或R'代表氢，R2代表氢、羟基、烷氧基、酰氧基、烷氧基羰氧基、烷硫基羰氧基、卤素、异硫氰基、氨基、烷基氨基、二烷基氨基、芳基氨基、酰氨基、烷氧基羰基氨基、烷硫基羰基氨基。R3和R4共同代表亚烷基或各自代表氢或烷基；R5、R6和R7可以相同或不同，各自代表氢、卤素、烷基、烷氧基、酰基或氰基），以及它们的制备方法和含有它们的除草组合物。
• Tetrahydrophthalimide compounds, and their production and use
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0083055A2

  公开（公告）日：1983-07-06

  A tetrahydrophthalimide compound of the formula: wherein R, is hydrogen, alkyl, lower cycloalkyl, lower alkyl(lower)cycloalkyl, lower cycloalkyl(lower)alkyl, lower alkoxy(lower)alkyl, lower alkenyl, lower cycloalkenyl, lower cycloalkenyl(lower)alkyl, phenyl, cyano(lower)alkyl, lower alkynyl, lower alkylideneamino, lower alkylthio(lower)alkyl, benzyl, halo(lower)alkyl or lower cycloalkylideneamino, R2 is hydrogen, lower alkyl or lower alkoxy, X is chlorine or bromine, Y is oxygen or imino and Z is oxygen or sulfur, which is useful as a herbicide.

  一种四氢邻苯二甲酰亚胺化合物，其式如下 其中 R 是氢、烷基、低级环烷基、低级(低级)环烷基、低级(低级)环烷基、低级(低级)烷氧基、低级烯基、低级环烯基、低级(低级)环烯基、苯基、氰基(低级)烷基、低级炔基、低级亚烷基氨基、低级烷硫基(低级)烷基、苄基、卤代(低级)烷基或低级环烷基、R2是氢、低级烷基或低级烷氧基，X是氯或溴，Y是氧或亚氨基，Z是氧或硫，可用作除草剂。