二十四烷酰胺 | 103212-81-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 二十四烷酰胺
• 英文名称: tetracosanamide
• 英文别名: Tetracosansaeureamid；Tetracosanamid
• CAS: 103212-81-3
• 化学式: C₂₄H₄₉NO
• 分子量: 367.659
• InChiKey: ZAYKUYSGARCXKQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  10
• 重原子数：
  26
• 可旋转键数：
  22
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.96
• 拓扑面积：
  43.1
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  二十四烷酰胺 在 lithium aluminium tetrahydride 作用下， 以 乙醚 为溶剂， 反应 17.0h， 以67%的产率得到二十四胺
  参考文献：
  名称：

  Porphyrin containing lipophilic amide groups as a photosensitizer for dye-sensitized solar cells

  摘要：

  合成了一种含有亲脂性酰胺基团的新型卟啉，并探索其在染料敏化太阳能电池中的应用。

  DOI：

  10.1039/c5ra10538b
• 作为产物：
  描述：

  lignoceroyl chloride 在 ammonium hydroxide 作用下， 反应 3.0h， 以80%的产率得到二十四烷酰胺
  参考文献：
  名称：

  Porphyrin containing lipophilic amide groups as a photosensitizer for dye-sensitized solar cells

  摘要：

  合成了一种含有亲脂性酰胺基团的新型卟啉，并探索其在染料敏化太阳能电池中的应用。

  DOI：

  10.1039/c5ra10538b

文献信息

• Novel sphingenine and derivatives thereof
  申请人：MECT CORPORATION

  公开号：EP0372571A3

  公开（公告）日：1991-07-03

  A sphingenine and derivatives thereof herein provided are represented by the following general formulas (I) and (II): in the formulas (I) and (II), R1 represents a hydrogen atom, an acetyl group or a methanesulfonyl group; R2 represents a hydrogen atom or an ethoxyethyl group; R3 represents an azido group, an amino group, an alkylamido group, an arylamido group, an aralkylamido group or a tetracosanamido group; R4 represents a hydrogen atom or an ethoxyethyl group; EE represents an ethoxy ethyl group; and n is an integer ranging from 1 to 22. These sphingenine and derivatives thereof are very useful as intermediates for synthesizing glycolipids and gangliosides which are effective as markers of tumours, in particular, in the preparation of ceramide parts of the glycolipids and gangliosides.

  本文提供的sfingosin及其衍生物由以下通用公式(I)和(II)表示：在公式(I)和(II)中，R1代表氢原子、乙酰基或甲磺基；R2代表氢原子或乙氧乙基基团；R3代表叠氮基、氨基、烷基酰胺基、芳基酰胺基、芳烷基酰胺基或二十四烷酰胺基；R4代表氢原子或乙氧乙基基团；EE代表乙氧乙基基团；n为1至22的整数。这些sfingosin及其衍生物在合成糖脂和神经节苷脂的中间体方面非常有用，这些化合物作为肿瘤标记物尤其有效，特别是在合成糖脂和神经节苷脂的鞘氨醇部分的制备中。
• Novel ultrasound contrast agents
  申请人：——

  公开号：US20040170565A1

  公开（公告）日：2004-09-02

  New ultrasound contrast agents that comprise microbubbles encapsulating a gas within a shell made from a blend of bipolar compounds having mixed carbon chain length. The compounds have hydrophobic groups selected from the group consisting of straight-chained alkyls, alkylethers, alkylthiolethers, alkyldisulfides, polyfluoroalkyls, and polyfluoroalkylethers having a carbon chain length greater than or equal to 16 and less than or equal to 32. The polar groups are connected to the hydrophobic groups by means of a linker. The polar head groups are selected from the group consisting of CO 2 -M + , SO 3 − M + , SO 4 − M + , PO 3 − M + , PO 4 − M + 2 , N(R) 4 + , a pyridinium or substituted pyridinium group, and a zwitterionic group; R is selected from the group consisting of —H, —CH 3 , alkyl, cycloalkyl, substituted cycloalkyls containing one or more heteroatoms, and benzyl and can be the same or different; and Z′ is a nonionic and M is a cation.

  新的超声造影剂包括微泡，其内部封装有气体，外壳由混合的双极化合物制成，其碳链长度混合。这些化合物具有疏水基团，所选的疏水基团来自于直链烷基，烷基醚，烷基硫醚，烷基二硫化物，多氟烷基和碳链长度大于或等于16且小于或等于32的多氟烷基醚。极性基团通过连接剂连接到疏水基团上。极性头基团来自于CO2-M+，SO3−M+，SO4−M+，PO3−M+，PO4−M+2，N(R)4+，吡啶或取代吡啶基团和带电离子的基团；R来自于—H，—CH3，烷基，环烷基，含有一个或多个杂原子的取代环烷基和苄基，并且可以相同也可以不同；Z′是非离子性的，M是一个阳离子。
• Polylactic acid resin composition and resin molded article thereof
  申请人：Dai-Ichi Kogyo Seiyaku Co., Ltd.

  公开号：EP2604654A2

  公开（公告）日：2013-06-19

  Provided are a polylactic acid resin composition excellent in impact resistance, migration resistance, and heat resistance, and excellent in productivity at the time of the mold forming thereof, and a resin molded article thereof. The polylactic acid resin composition includes a polylactic acid; a reaction product of at least one of a polyol and a polyol dehydration condensate, an alkylene oxide mainly formed of ethylene oxide, and a fatty acid having 12 to 24 carbon atoms; and a fatty acid amide.

  本发明提供了一种抗冲击性、抗迁移性和耐热性极佳且在模具成型时生产效率极高的聚乳酸树脂组合物及其树脂成型品。聚乳酸树脂组合物包括聚乳酸；多元醇和多元醇脱水缩合物、主要由环氧乙烷形成的环氧烷烃和具有 12 至 24 个碳原子的脂肪酸中至少一种的反应产物；以及脂肪酸酰胺。
• LUBRICATING OIL COMPOSITION, AND SLIDING MECHANISM USING LUBRICATING OIL COMPOSITION
  申请人：Idemitsu Kosan Co., Ltd

  公开号：EP2826844A1

  公开（公告）日：2015-01-21

  Disclosed is a lubricating oil composition for low-friction sliding materials, which is used in a sliding mechanism where a DLC film containing hydrogen in an amount of from 5 atom% to 50 atom% is formed on at least one sliding surface. The lubricating oil composition contains, in the lubricant base oil therein and based on the total amount of the composition, (A) an organic zinc dithiophosphate in an amount of from 0.005% by mass to 0.12% by mass in terms of the phosphorus concentration therein, (B) an amide-based friction-reducing agent in an amount of from 0.05% by mass to 5.0% by mass, and (C) an alkaline earth metal salicylate-based detergent and/or an alkaline earth metal sulfonate-based detergent in an amount of from 0.05% by mass to 0.5o by mass in terms of the alkaline earth metal concentration therein.

  本发明公开了一种用于低摩擦滑动材料的润滑油组合物，该组合物用于在至少一个滑动表面上形成含氢量为 5 原子％至 50 原子％的 DLC 膜的滑动机构中。 该润滑油组合物在其中的润滑油基础油中，根据组合物的总量，含有 (A) 有机二硫代磷酸锌，以其中的磷浓度计，含量为 0.005% （质量分数）至 0.12% （质量分数）；(B) 酰胺基减摩剂，含量为 0.05% (质量)至 5.0% (质量)，以及 (C) 碱土金属水杨酸酯类洗涤剂和/或碱土金属磺酸盐类洗涤剂，以其中碱土金属浓度计，用量为 0.05% (质量)至 0.5o (质量)。
• IMMUNITY INDUCER FOR SACCHARIDE ANTIGENS
  申请人：National Institute of Advanced Industrial Science and Technology

  公开号：EP2993182A1

  公开（公告）日：2016-03-09

  The present invention provides an immunity inducer and an immunity inducing method using same. The immunity inducer has an immunopotentiation effect on any target oligosaccharide antigen, in particular oligosaccharide antigens included in mammal-derived glycoprotein N-linked sugar chains; is capable of providing a monoclonal antibody having high specificity to and affinity with target oligosaccharide antigens; and has as an effective component thereof a glycolipid including a target oligosaccharide antigen (R) and indicated by general formula (2), or a salt thereof. General formula (2): R-Z-Y-CH(NH-CO-(CH2)n1-CH3-(CH2)n2-CH3 (in the formula, R indicates a straight-chain or branched oligosaccharide comprising 2-30 of at least one type of monosaccharide. Z indicates a single bond, O, S or NH, a linker bound to thiomethyl, amino methylated sugar alcohol. Y indicates -(CH2)m-. n1 indicates an integer of 2-40, n2 indicates an integer of 1-27, and m indicates an integer of 1-30).

  本发明提供了一种免疫诱导剂及其免疫诱导方法。该免疫诱导剂对任何目标寡糖抗原，特别是哺乳动物来源的糖蛋白 N-连接糖链中的寡糖抗原具有免疫增强作用；能够提供对目标寡糖抗原具有高特异性和亲和性的单克隆抗体；其有效成分为包括目标寡糖抗原（R）并由通式（2）表示的糖脂或其盐。通式（2）：R-Z-Y-CH(NH-CO-(CH2)n1-CH3-(CH2)n2-CH3（式中，R 表示直链或支链寡糖，包含 2-30 个至少一种类型的单糖。Z 表示单键、O、S 或 NH，与硫代甲基、氨基甲基化糖醇结合的连接体。n1 表示 2-40 的整数，n2 表示 1-27 的整数，m 表示 1-30 的整数）。