[2-[Bis(phenylsulfanyl)methyl]phenoxy]-tert-butyl-dimethylsilane | 292081-10-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [2-[Bis(phenylsulfanyl)methyl]phenoxy]-tert-butyl-dimethylsilane
• CAS: 292081-10-8
• 化学式: C₂₅H₃₀OS₂Si
• 分子量: 438.73
• InChiKey: UDMLRGZIVFUTQL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.65
• 重原子数：
  29
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.28
• 拓扑面积：
  59.8
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  苯甲酸 、 [2-[Bis(phenylsulfanyl)methyl]phenoxy]-tert-butyl-dimethylsilane 以69%的产率得到2-苯基-1-苯并呋喃
  参考文献：
  名称：

  Alkylidenation of esters on solid support and traceless synthesis of 2-substituted benzofurans

  摘要：

  Polymer-supported esters are smoothly converted into enol ethers using a titanocene alkylidene prepared by treatment of 2-tert-butyldimethylsilyloxybenzaldehyde diphenyldithioacetal with the low valent titanium species Cp2Ti[P(OEt)(3)](2). Treatment of the enol ethers with acid leads to the release of ketones from the Wang resin in high yield. Traceless solid-phase synthesis of 2-substituted benzofurans is achieved in a three-step termination procedure. (C) 2000 Published by Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4039(00)00753-x
• 作为产物：
  描述：

  苯硫酚 在 咪唑 、 三氟化硼乙醚 作用下， 以 溶剂黄146 、 N,N-二甲基甲酰胺 、 甲苯 为溶剂， 生成 [2-[Bis(phenylsulfanyl)methyl]phenoxy]-tert-butyl-dimethylsilane
  参考文献：
  名称：

  Alkylidenation of esters on solid support and traceless synthesis of 2-substituted benzofurans

  摘要：

  Polymer-supported esters are smoothly converted into enol ethers using a titanocene alkylidene prepared by treatment of 2-tert-butyldimethylsilyloxybenzaldehyde diphenyldithioacetal with the low valent titanium species Cp2Ti[P(OEt)(3)](2). Treatment of the enol ethers with acid leads to the release of ketones from the Wang resin in high yield. Traceless solid-phase synthesis of 2-substituted benzofurans is achieved in a three-step termination procedure. (C) 2000 Published by Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4039(00)00753-x

文献信息

• Alkylidenation of esters on solid support and traceless synthesis of 2-substituted benzofurans
  作者：Emma J Guthrie、Jackie Macritchie、Richard C Hartley

  DOI：10.1016/s0040-4039(00)00753-x

  日期：2000.6

  Polymer-supported esters are smoothly converted into enol ethers using a titanocene alkylidene prepared by treatment of 2-tert-butyldimethylsilyloxybenzaldehyde diphenyldithioacetal with the low valent titanium species Cp2Ti[P(OEt)(3)](2). Treatment of the enol ethers with acid leads to the release of ketones from the Wang resin in high yield. Traceless solid-phase synthesis of 2-substituted benzofurans is achieved in a three-step termination procedure. (C) 2000 Published by Elsevier Science Ltd.