4-(氯甲基)-5-(2-甲基-2-丙基)-2-糠酰胺 | 634171-67-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 4-(氯甲基)-5-(2-甲基-2-丙基)-2-糠酰胺
• 英文名称: 4-chloromethyl-5-tert-butylfuran-2-carboxamide
• 英文别名: 5-Tert-butyl-4-(chloromethyl)-2-furamide；5-tert-butyl-4-(chloromethyl)furan-2-carboxamide
• CAS: 634171-67-8
• 化学式: C₁₀H₁₄ClNO₂
• mdl: MFCD03765260
• 分子量: 215.68
• InChiKey: YFESPYPTUDIGBE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  56.2
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-(氯甲基)-5-(2-甲基-2-丙基)-2-糠酰胺 在 五氯化磷 、 三乙胺 作用下， 以 甲苯 为溶剂， 反应 7.33h， 生成 4-chloromethyl-5-tert-butylfuran-2-cyanofuran
  参考文献：
  名称：

  3- and 4-Dialkoxyphosphorylmethyl Derivatives of 5-tert-Butylfuran with Electron-Withdrawing Substituents in Position 2

  摘要：

  A procedure for preparing 3- and 4-halomethyl derivatives of 5-tert-butylfuran containing electron-withdrawing substituents in position 2 was developed, and phosphorylation of the resulting products under the conditions of the Arbuzov and Michaelis-Becker reactions was studied. 3-Bromomethyl derivatives are phosphorylated with trimethyl phosphite considerably faster than their 4-chloromethyl analogs. At the same time, 3- and 4- chloromethyl derivatives of N,N-diethyl-5-tert-butylfuran-2-carboxamide under the conditions of the Michaelis-Becker reaction only slightly differ in chemical properties.

  DOI：

  10.1023/b:rugc.0000018647.14195.32
• 作为产物：
  描述：

  methyl 4-acetoxymethyl-5-tert-butylfuran-2-carboxylate 在 氢氧化钾 、 ammonium hydroxide 、 氯化亚砜 作用下， 以 1,4-二氧六环 、 水 、 苯 为溶剂， 反应 12.0h， 生成 4-(氯甲基)-5-(2-甲基-2-丙基)-2-糠酰胺
  参考文献：
  名称：

  3- and 4-Dialkoxyphosphorylmethyl Derivatives of 5-tert-Butylfuran with Electron-Withdrawing Substituents in Position 2

  摘要：

  A procedure for preparing 3- and 4-halomethyl derivatives of 5-tert-butylfuran containing electron-withdrawing substituents in position 2 was developed, and phosphorylation of the resulting products under the conditions of the Arbuzov and Michaelis-Becker reactions was studied. 3-Bromomethyl derivatives are phosphorylated with trimethyl phosphite considerably faster than their 4-chloromethyl analogs. At the same time, 3- and 4- chloromethyl derivatives of N,N-diethyl-5-tert-butylfuran-2-carboxamide under the conditions of the Michaelis-Becker reaction only slightly differ in chemical properties.

  DOI：

  10.1023/b:rugc.0000018647.14195.32

文献信息

• PLANT PRIMING COMPOSITIONS AND METHODS OF USE THEREOF
  申请人：Zero Gravity Solutions, Inc.

  公开号：EP4021184A1

  公开（公告）日：2022-07-06
• [EN] PLANT PRIMING COMPOSITIONS AND METHODS OF USE THEREOF<br/>[FR] COMPOSITIONS D'AMORÇAGE DE PLANTE ET LEURS PROCÉDÉS D'UTILISATION
  申请人：ZERO GRAVITY SOLUTIONS INC

  公开号：WO2021041969A1

  公开（公告）日：2021-03-04

  Provided herein are compositions and methods to improve plant resistance to abiotic and biotic stress, thereby improving crop yield. Provided herein are compositions including zinc, copper, and an acid, where the acid is selected from citric acid, sulfuric acid, oxalic acid, humic acid, fulvic acid, boric acid, acetic acid, and a combination thereof. Certain embodiments optionally include ammonium sulfate. Compositions described herein have plant priming activity where the plant's defenses against abiotic and biotic stress are boosted.
• 3- and 4-Dialkoxyphosphorylmethyl Derivatives of 5-tert-Butylfuran with Electron-Withdrawing Substituents in Position 2
  作者：L. M. Pevzner

  DOI：10.1023/b:rugc.0000018647.14195.32

  日期：2003.11

  A procedure for preparing 3- and 4-halomethyl derivatives of 5-tert-butylfuran containing electron-withdrawing substituents in position 2 was developed, and phosphorylation of the resulting products under the conditions of the Arbuzov and Michaelis-Becker reactions was studied. 3-Bromomethyl derivatives are phosphorylated with trimethyl phosphite considerably faster than their 4-chloromethyl analogs. At the same time, 3- and 4- chloromethyl derivatives of N,N-diethyl-5-tert-butylfuran-2-carboxamide under the conditions of the Michaelis-Becker reaction only slightly differ in chemical properties.