1-(2-furyl)-2-phenylpropan-1-ol | 119216-35-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-(2-furyl)-2-phenylpropan-1-ol
• 英文别名: 1-(furan-2-yl)-2-phenylpropan-1-ol
• CAS: 119216-35-2；119216-36-3
• 化学式: C₁₃H₁₄O₂
• 分子量: 202.253
• InChiKey: AFLUJGKHIOQQCY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  33.4
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-(2-furyl)-2-phenylpropan-1-ol 在 间氯过氧苯甲酸 作用下， 以 氯仿 为溶剂， 生成 6-Hydroxy-2-(1-phenyl-ethyl)-6H-pyran-3-one
  参考文献：
  名称：

  呋喃的氧化。2.6-羟基-2H-吡喃-3（6H）-及其衍生物的合成和生物学性质。

  摘要：

  DOI：

  10.1021/jm00268a004
• 作为产物：
  描述：

  3,3-二甲基-1-苯基-2-丁酮 在 正丁基锂 、 sodium hydride 作用下， 以 四氢呋喃 、 乙醚 、 正己烷 、 正戊烷 为溶剂， 反应 4.25h， 生成 1-(2-furyl)-2-phenylpropan-1-ol
  参考文献：
  名称：

  通过裂解反应新制备苄基锌试剂

  摘要：

  空间受阻的均苄基醇锌盐的裂解容易进行，导致不含任何Wurtz偶联产物的苄基锌试剂。这些有机金属中间体与各种醛的反应以中等至良好的产率产生了新的均苄醇。还报道了这些新制备的苄基有机金属与亚烷基丙二酸酯的1，4-加成。

  DOI：

  10.1016/s0022-328x(00)00840-8

文献信息

• Reactions of higher order cyanocuprates derived from 2-lithiated furans: scope, limitations, and synthetic utility
  作者：John S Ng、James R Behling、Arthur L Campbell、Duy Nguyen、Bruce Lipshutz

  DOI：10.1016/0040-4039(88)85081-0

  日期：1988.1

  A general study on the chemistry of higher order organocuprates derived from 2-lithiated furans with enones, epoxides, aldehydes and halides is described.

  描述了对由2-锂化的呋喃与烯酮，环氧化物，醛和卤化物衍生的高级有机铜酸盐的化学性质的一般研究。
• Photopolymerization sensitizer composition
  申请人：Kawasaki Kasei Chemicals Ltd.

  公开号：US11352450B2

  公开（公告）日：2022-06-07

  The purpose of the present invention is to provide a photopolymerizable composition which can act as a photopolymerization sensitizer that is active against light having a wavelength falling within a wavelength range of from 300 to 500 nm, and which has such a property that coloring of a cured product produced by polymerizing a photopolymerizable composition containing the photopolymerization sensitizer is less. A photopolymerization sensitizer composition characterized by comprising a photopolymerization sensitizer containing an alkoxyanthracene compound represented by the formula (1) and a singlet oxygen quencher; and a photopolymerizable composition containing the photopolymerization sensitizer composition: in the formula (1), n represents an integer of 1 or 2; R represents a C1-12 alkyl group; and X represents a hydrogen atom or a C1-8 alkyl group.

  本发明的目的是提供一种可光聚合组合物，该组合物可作为光聚合敏化剂，对波长在300至500纳米范围内的光具有活性，并且具有这样一种特性，即通过聚合含有该光聚合敏化剂的可光聚合组合物而生产的固化产品着色较少。 一种光聚合增感剂组合物，其特征在于包括含有式（1）表示的烷氧蒽化合物和单线态氧淬灭剂的光聚合增感剂；以及含有该光聚合增感剂组合物的可光聚合组合物： 式（1）中，n 代表 1 或 2 的整数；R 代表 C1-12 烷基；X 代表氢原子或 C1-8 烷基。
• PHOTOPOLYMERIZATION SENSITIZER COMPOSITION
  申请人：Kawasaki Kasei Chemicals Ltd.

  公开号：US20210079127A1

  公开（公告）日：2021-03-18

  [OBJECT] The purpose of the present invention is to provide a photopolymerizable composition which can act as a photopolymerization sensitizer that is active against light having a wavelength falling within a wavelength range of from 300 to 500 nm, and which has such a property that coloring of a cured product produced by polymerizing a photopolymerizable composition containing the photopolymerization sensitizer is less. [SOLUTION TO PROBLEM] A photopolymerization sensitizer composition characterized by comprising a photopolymerization sensitizer containing an alkoxyanthracene compound represented by the formula (1) and a singlet oxygen quencher; and a photopolymerizable composition containing the photopolymerization sensitizer composition: in the formula (1), n represents an integer of 1 or 2; R represents a C 1-12 alkyl group; and X represents a hydrogen atom or a C 1-8 alkyl group.
• New preparation of benzylic zinc reagents via a fragmentation reaction
  作者：Claudia Piazza、Nicolas Millot、Paul Knochel

  DOI：10.1016/s0022-328x(00)00840-8

  日期：2001.4

  fragmentation of sterically hindered homobenzylic zinc alcoholates proceeds readily leading to benzylic zinc reagents free from any Wurtz-coupling product. Reaction of these organometallic intermediates with various aldehydes produces new homobenzylic alcohols in moderate to good yields. A 1,4-addition of these newly prepared benzylic organometallics to an alkylidenemalonate is also reported.

  空间受阻的均苄基醇锌盐的裂解容易进行，导致不含任何Wurtz偶联产物的苄基锌试剂。这些有机金属中间体与各种醛的反应以中等至良好的产率产生了新的均苄醇。还报道了这些新制备的苄基有机金属与亚烷基丙二酸酯的1，4-加成。
• Oxidation of furans. 2. Synthesis and biological properties of 6-hydroxy-2H-pyran-3(6H)-ones and derivatives
  作者：Real Laliberte、Geroges Medawar、Yvon Lefebvre

  DOI：10.1021/jm00268a004

  日期：1973.10