monoethylmaleic acid | 13074-60-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: monoethylmaleic acid
• 英文别名: 2-ethylmaleic acid；ethyl-maleic acid；Aethyl-maleinsaeure；methyl citraconic acid；ethylmaleic acid；2-Butenedioic acid, 2-ethyl-, (2Z)-；(Z)-2-ethylbut-2-enedioic acid
• CAS: 13074-60-7
• 化学式: C₆H₈O₄
• 分子量: 144.127
• InChiKey: SASYHUDIOGGZCN-ARJAWSKDSA-N

物化性质

• 沸点：
  336.3±25.0 °C(Predicted)
• 密度：
  1.307±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  10
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  monoethylmaleic acid 在 甲酸 、 四环素 、 anthraquinone-2,6-disulfonate 作用下， 以 水 为溶剂， 反应 45.0h， 生成 (S)-(-)-ethylsuccinic acid
  参考文献：
  名称：

  Preparation of (S)-2-substituted succinates by stereospecific reductions of fumarate and derivatives with resting cells of Clostridium formicoaceticum

  摘要：

  Fumarate derivatives have been reduced to (S)-2-methylsuccinate 2a, (S)-2-ethylsuccinate 3a and (S)-2-chlorosuccinate 4a in up to 1 M concentrations with Clostridium formicoaceticum. Formate was the electron donor and viologens or anthraquinone-2,6-disulphonate acted as artificial electron mediators. Reductions with freeze-dried cells in (H2O)-H-2-buffers led to the (2R,3S)-[2,3-H-2]-dideuterated succinate derivatives. The productivity numbers(1) ranged from 450 to 5000 and the enantiomeric excess of all (S)-2-substituted succinates was greater than or equal to 99%.

  DOI：

  10.1016/s0040-4020(01)85677-5
• 作为产物：
  描述：

  2-ethyl-3-hydroxy-succinic acid 生成 monoethylmaleic acid
  参考文献：
  名称：

  母乳喂养和超重的风险。

  摘要：

  DOI：

  10.1001/jama.286.12.1448

文献信息

• [EN] FLUOROALKYLFLUORENE DERIVATIVES<br/>[FR] DÉRIVÉS FLUOROALKYLFLUORÈNE
  申请人：LOMOX LTD

  公开号：WO2015159098A1

  公开（公告）日：2015-10-22

  There are provided compounds of the formula D-S1-A-S2-B1 wherein A comprises a 2,7- disubstituted 9,9-fluoroalkyl fluorene diradical of the formula wherein S1, S2, D and B1 have meanings given in the description that are useful as charge transport and emissive materials for the fabrication of electronic devices such as diodes, transistors, and photovoltaic devices.

  提供了符合以下公式的化合物 D-S1-A-S2-B1，其中 A 包括公式中的 2,7- 二取代 9,9-氟烷基萘二自由基，其中 S1、S2、D 和 B1 的含义如描述中所述，这些化合物可用作电荷传输和发射材料，用于制造电子器件，如二极管、晶体管和光伏器件。
• [EN] CROSS-LINKABLE ORGANOMETALLIC LIGHT EMITTING LIGANDS AND COMPLEXES<br/>[FR] LIGANDS ET COMPLEXES ÉLECTROLUMINESCENTS ORGANOMÉTALLIQUES RÉTICULABLES
  申请人：LOMOX LTD

  公开号：WO2018162880A1

  公开（公告）日：2018-09-13

  The present invention relates to a 1, 4 bidentate ligand comprising first and second ligand centres, wherein the first ligand centre is an sp2-hybridised carbon or a nitrogen atom; wherein the second ligand centre is a nitrogen atom in a five- or six-membered aromatic or hetero-aromatic ring, said ring having a substantially linear substituent T1 meta or para to the nitrogen atom; wherein T1 has the fomula (1) : -Ar1 a -Y1 b-Ar2-[Y2 c-Ar2]d-S-B and wherein T1 is attached to the ring by X1, wherein X1 is a bond, a methylene group, a substituted methylene group, an oxygen atom or a sulphur atom, wherein each Ar1 and Ar2 are independently selected from the group of C6 to C20 aromatic and C4 to C20 heteroaromatic groups, wherein Y1 and each Y2 is independently an optionally substituted C2 or acetonitrile trans double-bond linking moiety, wherein a is 0, 1, 2 or 3, wherein b is 0, 1 or 2, wherein each c is independently 0, 1 or 2, wherein d is 0, 1,2, 3 or 4, S is a flexible spacer, and B represents a moiety having one or more cross-linkable functionalities.

  本发明涉及一种1,4-双齿配体，包括第一和第二配体中心，其中第一配体中心是sp2杂化碳或氮原子；其中第二配体中心是五元或六元芳香或杂芳环中的氮原子，所述环具有与氮原子的meta位或para位上的基团T1近似线性；其中T1的化学式为：-Ar1 a -Y1 b-Ar2-[Y2 c-Ar2]d-S-B，其中T1通过X1连接到环上，其中X1是键，亚甲基基团，取代亚甲基基团，氧原子或硫原子，其中每个Ar1和Ar2分别从C6到C20芳香族和C4到C20杂芳族中选择，其中Y1和每个Y2独立地是选择性取代的C2或乙腈反式双键连接基团，其中a为0、1、2或3，b为0、1或2，每个c独立地为0、1或2，d为0、1、2、3或4，S是柔性间隔物，B代表具有一个或多个可交联官能基的基团。
• PROCESS FOR PREPARING IONIC LIQUIDS BY ANION EXCHANGE
  申请人：Massonne Klemens

  公开号：US20100217010A1

  公开（公告）日：2010-08-26

  Process for preparing salts of the formula I (B + ) n x A y− where B is a cation comprising at least one nitrogen atom, A is an anion and n is an integer from 1 to 3, x and y are each an integer from 1 to 3 and the product of x and y is equal to n, by reacting salts of the formula II (B + ) n x A y− where B and n, x and y are as defined above and C is a compound which has one or more carboxylate groups (referred to as carboxylate for short) and is different from A, with the ammonium salt of the anion A or with the protic acid of the anion A in the presence of ammonia.

  制备I(B+)nxAy的盐的过程-其中B是至少含有一个氮原子的阳离子，A是阴离子，n是1到3的整数，x和y分别是1到3的整数，且x和y的乘积等于n，通过反应II(B+)nxAy的盐来实现-其中B和n、x和y如上定义，C是一种具有一个或多个羧酸基团（简称为羧酸）且与A不同的化合物，与阴离子A的铵盐或其质子酸在氨的存在下反应。
• COPOLYMERS AND COMPOSITIONS WITH ANTI-ADHESIVE AND ANTIMICROBIAL PROPERTIES
  申请人：BASF SE

  公开号：US20160235062A1

  公开（公告）日：2016-08-18

  The invention relates to a copolymer exhibiting both antimicrobial and anti-adhesive properties as well as to a hydrogel. Said hydrogel is obtained from the inventive copolymer and a substrate. Another part of the invention is a process for making the hydrogel, as well as different uses of the inventive copolymer as well as of the hydrogel.

  该发明涉及一种既具有抗菌和抗粘附性能的共聚物，又涉及一种水凝胶。所述水凝胶是由该创新共聚物和基质制得的。该发明的另一部分是制备水凝胶的方法，以及该创新共聚物和水凝胶的不同用途。
• [EN] DIBENZO[D,B]SILOLE-BASED REACTIVE MESOGENS<br/>[FR] MÉSOGÈNES RÉACTIFS À BASE DE DIBENZO[D,B]SILOLE
  申请人：LOMOX LTD

  公开号：WO2018065786A1

  公开（公告）日：2018-04-12

  The present invention provides a compound of Formula (I) D-S1-A-S2 B1, Formula (I) wherein a represents a conjugated chain of from 1 to 20 aromatic moieties independently selected from the group consisting of aromatic moieties, heteroaromatic moieties and E moieties, provided that A includes at least one E moiety, wherein E is selected from the group consisting of E1 being a dibenzo[d,b]silole moiety of the structure, E2 being a moiety of the structure and E3 being a moiety of the structure wherein E is connected in the conjugated chain of A and optionally to S1 or to S2 through covalent bonds at Y and Z; wherein each R is independently selected from the group consisting of straight chain or branched C1-C20 alkyl and C2-C20 alkenyl, optionally wherein from 1 to 5 CH2 groups are each replaced by an oxygen, provided that no acetal, ketal, peroxide or vinyl ether is present in the R group, and optionally wherein each H bonded to a C in each R group may independently be replaced by a halogen; wherein the X moieties are the same and are selected from the group consisting of hydrogen, straight chain or branched C1-C8 alkyl, straight chain or branched C1-C8 alkoxyl and a halogen, wherein each E moiety may have the same or different X moieties, wherein W is either an oxygen or sulfur atom, D represents a moiety having one or more cross-linkable functionalities, S1 and S2 are flexible linker groups; and B1 represents a moiety having one or more cross-linkable functionalities or a hydrogen atom, with the proviso that when B1 represents a hydrogen atom, D represents a moiety having at least two cross-linkable functionalities.

  本发明提供了一种化合物，其化学式为（I）D-S1-A-S2 B1，其中化学式（I）中的a代表一个由1到20个芳香基团组成的共轭链，这些芳香基团可以独立地选自芳香基团、杂芳基团和E基团的组合，其中A至少包括一个E基团，其中E选自包括结构为dibenzo[d,b]硅烯基团的E1、结构为E2的基团和结构为E3的基团的组合，其中E连接在A的共轭链中，并且可以通过在Y和Z处与S1或S2形成共价键连接；其中每个R可以独立地选自直链或支链的C1-C20烷基和C2-C20烯基的组合，可选地，其中从1到5个CH2基团中的每个都被氧替代，前提是R基团中没有存在缩醛、缩酮、过氧化物或乙烯醚，并且每个连接到R基团中的C的H可以独立地被卤素替代；其中X基团相同，选自氢、直链或支链的C1-C8烷基、直链或支链的C1-C8烷氧基和卤素，每个E基团可能具有相同或不同的X基团，W为氧或硫原子，D代表具有一个或多个可交联官能团的基团，S1和S2是柔性连接基团；B1代表具有一个或多个可交联官能团或氢原子的基团，但有一个条件，即当B1代表氢原子时，D代表至少具有两个可交联官能团的基团。