9-methyl-7-oxo-7,13-dihydrochromeno[2,3-b][1,5]benzodiazepine | 71121-82-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯二氮卓类
• 英文名称: 9-methyl-7-oxo-7,13-dihydrochromeno[2,3-b][1,5]benzodiazepine
• 英文别名: 2-methyl-6H-benzo[b]chromeno[2,3-e][1,4]diazepin-13-one；2-Methyl-(1)benzopyrano(2,3-b)(1,5)benzodiazepin-13(6H)-one；2-methyl-6H-chromeno[2,3-b][1,5]benzodiazepin-13-one
• CAS: 71121-82-9
• 化学式: C₁₇H₁₂N₂O₂
• 分子量: 276.294
• InChiKey: NGRBCJLXDOSDST-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  21
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  50.7
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  9-methyl-7-oxo-7,13-dihydrochromeno[2,3-b][1,5]benzodiazepine 、 苯甲酰氯 以84%的产率得到
  参考文献：
  名称：

  REDDY, G. J.;RAO, A. V. S., CURR. SCI., INDIA, 1981, 50, N 2, 84-86

  摘要：

  DOI：
• 作为产物：
  描述：

  6-甲基-4-氧-4H-1-苯并吡喃-3-甲醛 在 四氯苯醌 作用下， 以 氯仿 、 xylene 为溶剂， 生成 9-methyl-7-oxo-7,13-dihydrochromeno[2,3-b][1,5]benzodiazepine
  参考文献：
  名称：

  Reactions of Formylchromone Derivatives; 3¹. A Facile Synthesis of Fused Benzopyrano-benzothiazepinones, -benzoxazepinones, and -benzodiazepinones

  摘要：

  DOI：

  10.1055/s-1979-28669

文献信息

• Reactivity of 6-Methylchromone-3-carbonitrile Towards Some Nitrogen Nucleophilic Reagents
  作者：Magdy A. Ibrahim、Nasser M. El-Gohary、Sara Said

  DOI：10.3987/com-18-13874

  日期：——

  The chemical reactivity of 6-methylchromone-3-carbonitrile (1) was studied towards a variety of nitrogen nucleophiles. A variety of products was obtained from the reaction of carbonitrile 1 with hydrazine hydrate, S-benzyl dithiocarbazate, isonicotinic acid hydrazide and cyanoacetohydrazide. A diversity of Schiff bases bearing 2-amino-6-methylchromone linked variable heterocyclic systems was efficiently synthesized. Reaction of carbonitrile 1 with guanidine and cyanoguanidine resulted in ring conversion producing chromeno[4,3-d]pyrimidines. Reaction of carbonitrile 1 was also studied towards some 1,4-binucleophiles.
• Heterocyclic Systems; 9¹. Reaction of 4-Oxo-4<i>H</i>-1-benzopyran-3-carboxaldehydes(3-Formylchromones) with 1,2-Diamines
  作者：C. K. Ghosh、S. Khan

  DOI：10.1055/s-1980-29176

  日期：——
• Reactions of Formylchromone Derivatives; 3¹. A Facile Synthesis of Fused Benzopyrano-benzothiazepinones, -benzoxazepinones, and -benzodiazepinones
  作者：Alan O. Fitton、Peter G. Houghton、Hans Suschitzky

  DOI：10.1055/s-1979-28669

  日期：——
• FITTON A. O.; HOUGHTON P. G.; SUSCHITZKY H., SYNTHESIS, 1979, NO 5, 337-339
  作者：FITTON A. O.、 HOUGHTON P. G.、 SUSCHITZKY H.

  DOI：——

  日期：——
• GHOSH, C. K.;BANDVOPADHYANY, C.;MORIN, CH., J. CHEM. SOC. PERKIN TRANS., 1983, 1, N 9, 1989-1994
  作者：GHOSH, C. K.、BANDVOPADHYANY, C.、MORIN, CH.

  DOI：——

  日期：——