6-甲基十六烷酸 | 17670-88-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 6-甲基十六烷酸
• 英文名称: ε-Methylpalmitinsaeure
• 英文别名: 6-Methyl-palmitinsaeure；6-methyl-hexadecanoic acid；6-Methyl-hexadecansaeure；Hexadecanoic acid, 6-methyl-；6-methylhexadecanoic acid
• CAS: 17670-88-1
• 化学式: C₁₇H₃₄O₂
• 分子量: 270.456
• InChiKey: ZGIDDSJOJKBXCZ-UHFFFAOYSA-N

物化性质

• 熔点：
  30.5-31 °C
• 沸点：
  173 °C(Press: 2 Torr)
• 密度：
  0.889±0.06 g/cm3(Predicted)
• LogP：
  7.500 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  6.6
• 重原子数：
  19
• 可旋转键数：
  14
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  甲基2-甲基月桂酸酯 在 盐酸 、 氢氧化钾 、 lithium aluminium tetrahydride 、 一水合肼 、 lithium bromide 作用下， 以 吡啶 、 甲醇 、 乙醇 、 水 、 丙酮 、 二乙二醇 为溶剂， 反应 30.0h， 生成 6-甲基十六烷酸
  参考文献：
  名称：

  Dobner; Elsner; Nuhn, Pharmazie, 1989, vol. 44, # 11, p. 758 - 760

  摘要：

  DOI：

文献信息

• Weitzel; Wojahn, Hoppe-Seyler's Zeitschrift fur Physiologische Chemie, 1951, vol. 287, p. 65,88
  作者：Weitzel、Wojahn

  DOI：——

  日期：——
• SCATTERED BRANCHED-CHAIN FATTY ACIDS AND BIOLOGICAL PRODUCTION THEREOF
  申请人：THE PROCTER & GAMBLE COMPANY

  公开号：EP2524049B1

  公开（公告）日：2015-10-28
• Scattered Branched-Chain Fatty Acids And Biological Production Thereof
  申请人：Saunders Charles Winston

  公开号：US20110166370A1

  公开（公告）日：2011-07-07

  Methods and cells for producing scattered branched-chain fatty acids are provided. For example, the invention provides a method for producing branched-chain fatty acid comprising a methyl on one or more even number carbons. The method comprises culturing a cell comprising an exogenous or overexpressed polynucleotide comprising a nucleic acid sequence encoding a polypeptide that catalyzes the conversion of propionyl-CoA to methylmalonyl-CoA and/or an exogenous or overexpressed polynucleotide comprising a nucleic acid sequence encoding a polypeptide that catalyzes the conversion of succinyl-CoA to methylmalonyl-CoA, under conditions allowing expression of the polynucleotide(s) and production of branched-chain fatty acid. The cell produces more branched-chain fatty acid comprising a methyl on one or more even number carbons than an otherwise similar cell that does not comprise the polynucleotide(s). A cell that produces branched-chain fatty acid and the branched-chain fatty acid also are provided.
• [EN] SCATTERED BRANCHED-CHAIN FATTY ACIDS AND BIOLOGICAL PRODUCTION THEREOF<br/>[FR] ACIDES GRAS DISPERSÉS À CHAÎNE RAMIFIÉE ET PRODUCTION BIOLOGIQUE ASSOCIÉE
  申请人：PROCTER & GAMBLE

  公开号：WO2011088088A1

  公开（公告）日：2011-07-21

  Methods and cells for producing scattered branched- chain fatty acids are provided. For example, the invention provides a method for producing branched- chain fatty acid comprising a methyl on one or more even number carbons. The method comprises culturing a cell comprising an exogenous or overexpressed polynucleotide comprising a nucleic acid sequence encoding a polypeptide that catalyzes the conversion of propionyl-CoA to methylmalonyl - CoA, such as propionyl - CoA carboxylase, and/or an exogenous or overexpressed polynucleotide comprising a nucleic acid sequence encoding a polypeptide that catalyzes the conversion of succinyl-CoA to methylmalonyl - CoA, such as methylmalonyl - CoA mutase, under conditions allowing expression of the polynucleotide (s) and production of branched- chain fatty acid. The cell produces more branched- chain fatty acid comprising a methyl on one or more even number carbons than an otherwise similar cell that does not comprise the polynucleotide (s). A cell that produces branched- chain fatty acid further comprising exogenous or overexpressed acyl transferase lacking polyketide synthetic activity and the branched- chain fatty acid also are provided.
• Dobner, B.; Nuhn, P.; Gutheil, M., Zeitschrift für Chemie, 1984, vol. 24, # 8, p. 308
  作者：Dobner, B.、Nuhn, P.、Gutheil, M.

  DOI：——

  日期：——