Cyclopropylimino-morpholin-4-yl-oxo-phenyl-lambda6-sulfane | 1523524-07-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 恶嗪烷类
• 英文名称: Cyclopropylimino-morpholin-4-yl-oxo-phenyl-lambda6-sulfane
• 英文别名: cyclopropylimino-morpholin-4-yl-oxo-phenyl-λ6-sulfane
• CAS: 1523524-07-3
• 化学式: C₁₃H₁₈N₂O₂S
• 分子量: 266.364
• InChiKey: JDOOFTSEZJBAJV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  50.3
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  tert-butyl[morpholin-4-yl(oxido)phenyl-λ6-sulfanylidene]carbamate 在 2,2'-联吡啶 、 copper diacetate 、 sodium carbonate 、 三氟乙酸 作用下， 以 二氯甲烷 为溶剂， 反应 18.0h， 生成 Cyclopropylimino-morpholin-4-yl-oxo-phenyl-lambda6-sulfane
  参考文献：
  名称：

  A mild and efficient copper-catalyzed N-arylation of unprotected sulfonimidamides using boronic acids

  摘要：

  An efficient and low cost copper catalyzed system for N-arylation of sulfonimidamides has been developed. The reaction proceeds at room temperature under base free conditions. Various N-aryl, N-heteroaryl, and N-cyclopropyl sulfonimidamides were obtained in good to excellent yields. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.11.084

文献信息

• A mild and efficient copper-catalyzed N-arylation of unprotected sulfonimidamides using boronic acids
  作者：S.R.K. Battula、G.V. Subbareddy、I.E. Chakravarthy

  DOI：10.1016/j.tetlet.2013.11.084

  日期：2014.1

  An efficient and low cost copper catalyzed system for N-arylation of sulfonimidamides has been developed. The reaction proceeds at room temperature under base free conditions. Various N-aryl, N-heteroaryl, and N-cyclopropyl sulfonimidamides were obtained in good to excellent yields. (C) 2013 Elsevier Ltd. All rights reserved.