An opto-acoustic wave sensor provides for the detection, the determination of the location, and/or the quantification of an amount of a chemical species using a selective chemical interaction of the chemical species and a selective reagent disposed on a surface of the opto-acoustic wave sensing element. The amount of the chemical species is detected by a change in the mass of the opto-acoustic wave-sensing element, which results in a detectable change in a resonance frequency of the sensing element. The identity of the chemical species is ascertained by an optical property of the product of the selective chemical interaction such as an absorbance or an intensity or other properties of the electromagnetic radiation emitted by the product. The sensor may be used in a method for detecting, determining the location or the spatial distribution of, and quantifying a wide range of chemical compounds, such as for monitoring chemicals in environment and industrial facilities and determining products in a combinatorial experiment.
一种光声波传感器可利用
化学物质与设置在光声波传感元件表面的选择性试剂之间的选择性
化学作用来检测、确定
化学物质的位置和/或量化
化学物质的数量。光声波传感元件的质量变化会导致传感元件的共振频率发生可检测的变化,从而检测出
化学物质的数量。
化学物质的特性可通过选择性
化学作用产物的光学特性(如吸光度或强度)或产物发射的电磁辐射的其他特性来确定。该传感器可用于检测、确定各种化合物的位置或空间分布以及量化各种化合物的方法,例如用于监测环境和工业设施中的
化学品以及确定组合实验中的产物。