1,3-dichloro-5-((3,3-dichloroallyl)oxy)-2-(3-(4-phenoxyphenoxy)propoxy)benzene

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,3-dichloro-5-((3,3-dichloroallyl)oxy)-2-(3-(4-phenoxyphenoxy)propoxy)benzene
• 英文别名: 1,3-Dichloro-5-(3,3-dichloroprop-2-enoxy)-2-[3-(4-phenoxyphenoxy)propoxy]benzene；1,3-dichloro-5-(3,3-dichloroprop-2-enoxy)-2-[3-(4-phenoxyphenoxy)propoxy]benzene
• 化学式: C₂₄H₂₀Cl₄O₄
• 分子量: 514.232
• InChiKey: BIZZGWUOKSACNS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.4
• 重原子数：
  32
• 可旋转键数：
  11
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  36.9
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  4-(3,3-dichloroallyloxy)phenol 在 磺酰氯 、 potassium carbonate 、 二正丁胺 作用下， 以 N,N-二甲基甲酰胺 、 甲苯 、 乙腈 为溶剂， 反应 2.0h， 生成 1,3-dichloro-5-((3,3-dichloroallyl)oxy)-2-(3-(4-phenoxyphenoxy)propoxy)benzene
  参考文献：
  名称：

  Design, synthesis and insecticidal evaluation of aryloxy dihalopropene derivatives

  摘要：

  Plutella xylostella (P. xylostella) is a highly migratory, cosmopolitan species and one of the most important pest of cruciferous crops worldwide. Pyridalyl as a novel class of insecticides has good efficacy against P. xylostella. On the basis of the commercial insecticide pyridalyl, a series of new aryloxy dihalopropene derivatives were designed and synthesized by using Intermediate Derivatization Methods. Their chemical structures were confirmed by H-1 NMR, high-resolution mass spectrum (HRMS), and single-crystal X-ray diffraction analysis. The insecticidal activities of the new compounds against P. xylostella were evaluated. The results of bioassays indicated that most of the compounds showed moderate to high activities at the tested concentration, especially compounds 10e and 10g displayed more than 75% insecticidal activity against P. xylostella at 6.25 mg/L, while pyridalyl showed 50% insecticidal activity at the same concentration. The field trials result of the insecticidal activities showed that compound 10e as a 10% emulsifiable concentrate (EC) was effective in the control of P. xylostella at 75-150 g a. i./ha, and the mortality of P. xylostella for treatment with compound 10e at 75 g a. i./ha was equivalent to pyridalyl at 105 g a.i./ha. (C) 2015 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmc.2015.09.030

文献信息

• ARYLOXY DIHALOPROPENYL ETHER COMPOUNDS AND USES THEREOF
  申请人：Liu Changling

  公开号：US20130303541A1

  公开（公告）日：2013-11-14

  The present invention discloses an aryloxy dihalopropenyl ether compound with the structure shown as general formula (I), of which the group definitions can be seen in the specification. The present invention also discloses the use of the compound with general formula (I) as an insecticide in the agricultural field and an insecticidal composition using the compound with general formula (I) as an active component.

  本发明揭示了一种具有通用式(I)所示结构的芳氧基二卤代丙烯醚化合物，其中群定义可在说明书中看到。本发明还揭示了将具有通用式(I)的化合物用作农业领域中的杀虫剂，以及使用具有通用式(I)的化合物作为活性成分的杀虫组合物。
• ARYLOXY DIHALOPROPENYL ETHER COMPOUND AND USE THEREOF
  申请人：Sinochem Corporation

  公开号：EP2692723A1

  公开（公告）日：2014-02-05

  The present invention discloses an aryloxy dihalopropenyl ether compound with the structure shown as general formula (I), of which the group definitions can be seen in the specification. The present invention also discloses the use of the compound with general formula (I) as an insecticide in the agricultural field and an insecticidal composition using the compound with general formula (1) as an active component.

  本发明公开了一种结构如通式（I）所示的芳氧基二卤丙烯基醚化合物，其组定义见说明书。本发明还公开了通式（I）化合物作为杀虫剂在农业领域的用途，以及以通式（1）化合物为活性成分的杀虫组合物。
• US8969332B2
  申请人：——

  公开号：US8969332B2

  公开（公告）日：2015-03-03
• Design, synthesis and insecticidal evaluation of aryloxy dihalopropene derivatives
  作者：Ji-Chun Yang、Miao Li、Qiao Wu、Chang-Ling Liu、Xiu-Hui Chang

  DOI：10.1016/j.bmc.2015.09.030

  日期：2016.2

  Plutella xylostella (P. xylostella) is a highly migratory, cosmopolitan species and one of the most important pest of cruciferous crops worldwide. Pyridalyl as a novel class of insecticides has good efficacy against P. xylostella. On the basis of the commercial insecticide pyridalyl, a series of new aryloxy dihalopropene derivatives were designed and synthesized by using Intermediate Derivatization Methods. Their chemical structures were confirmed by H-1 NMR, high-resolution mass spectrum (HRMS), and single-crystal X-ray diffraction analysis. The insecticidal activities of the new compounds against P. xylostella were evaluated. The results of bioassays indicated that most of the compounds showed moderate to high activities at the tested concentration, especially compounds 10e and 10g displayed more than 75% insecticidal activity against P. xylostella at 6.25 mg/L, while pyridalyl showed 50% insecticidal activity at the same concentration. The field trials result of the insecticidal activities showed that compound 10e as a 10% emulsifiable concentrate (EC) was effective in the control of P. xylostella at 75-150 g a. i./ha, and the mortality of P. xylostella for treatment with compound 10e at 75 g a. i./ha was equivalent to pyridalyl at 105 g a.i./ha. (C) 2015 Elsevier Ltd. All rights reserved.