1,2,3-tris(benzyloxy)propane | 102956-89-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 英文名称: 1,2,3-tris(benzyloxy)propane
• 英文别名: 1,2,3-tribenzyloxypropane；tri-O-benzylglycerol；Benzene, 1,1',1''-[1,2,3-propanetriyltris(oxymethylene)]tris-；1,3-bis(phenylmethoxy)propan-2-yloxymethylbenzene
• CAS: 102956-89-8
• 化学式: C₂₄H₂₆O₃
• 分子量: 362.469
• InChiKey: OIJSSMNQUWGQGT-UHFFFAOYSA-N

物化性质

• 沸点：
  491.1±45.0 °C(Predicted)
• 密度：
  1.101±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  27
• 可旋转键数：
  11
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  27.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1,2,3-tris(benzyloxy)propane 在 四氯化锡 、 pyridinium chlorochromate 作用下， 以 二氯甲烷 为溶剂， 反应 7.0h， 生成 1,3-二苄氧基丙酮
  参考文献：
  名称：

  Synthesis and stereoselective aldol reaction of dihydroxyacetone derivatives

  摘要：

  DOI：

  10.1016/s0040-4039(00)00969-2
• 作为产物：
  描述：

  苄基缩水甘油醚 在 四丁基碘化铵 、 sodium hydride 作用下， 反应 28.0h， 生成 1,2,3-tris(benzyloxy)propane
  参考文献：
  名称：

  Chong, J. Michael; Sokoll, Kenneth K., Organic Preparations and Procedures International, 1993, vol. 25, # 6, p. 639 - 647

  摘要：

  DOI：

文献信息

• Regioselective de-O-benzylation with Lewis acids
  作者：Hiroshi Hori、Yoshihiro Nishida、Hiroshi Ohrui、Hiroshi Meguro

  DOI：10.1021/jo00267a022

  日期：1989.3
• Enhanced reactivity of secondary hydroxyl groups in the O-alkylation of carbohydrate-related primary-secondaryvic-glycols. Regioselective 2-O-benzylation of 1,3:2,4-di-O-ethylidene-D-glucitol
  作者：E. A. El'perina、M. I. Struchkova、M. I. Serkebaev、E. P. Serebryakov

  DOI：10.1007/bf00704019

  日期：1993.4

  Partial O-alkylation of 1,3:2,4-di-O-ethylidene-D-glucitol (1a), 1,2-O-isopropylidene-3-O-methyl-alpha-D-glucofuranose (1b), and R-(+)-1-O-benzylglycerol (1c) with benzyl chloride in a KOH/DMSO system results in products of monoalkylation at the secondary (4a-c) and at the primary hydroxyl (2a-c) in ratios of over 95:5 (a), -2:1 (b), and -1:1 (c), whereas (+/-)propane-1,2-diol (1d) gives only the product of 1-O-benzylation (2d). A qualitatively similar result is observed upon O-alkylation of diols (la-e) with 2-methoxyethanol tosylate.
• Differential Cleavage of Arylmethyl Ethers: Reactivity of 2,6-Dimethoxybenzyl Ethers
  作者：J. R. Falck、D. K. Barma、Rachid Baati、Charles Mioskowski

  DOI：10.1002/1521-3773(20010401)40:7<1281::aid-anie1281>3.0.co;2-b

  日期：2001.4.1
• HORI, HIROSHI;NISHIDA, YOSHIHIRO;OHRUI, HIROSHI;MEGURO, HIROSHI, J. ORG. CHEM., 54,(1989) N, C. 1346-1353
  作者：HORI, HIROSHI、NISHIDA, YOSHIHIRO、OHRUI, HIROSHI、MEGURO, HIROSHI

  DOI：——

  日期：——
• ETHER-ESTER PLASTICIZERS
  申请人：Schaefer F. George

  公开号：US20070123622A1

  公开（公告）日：2007-05-31

  The present invention provides compounds having both a pendent ether group and a pendent ester group that are useful as plasticizers for polymer resin and methods of making and using the same. In one embodiment of the invention, compounds according to the invention are formed by converting at least one, but not all, of the hydroxyl groups of a polyol having three or more hydroxyl groups (e.g., gylcerol, pentaerythritol or dipentaerythritol) to a pendent ether group to form a partially-etherized intermediate, and then converting at least one of the remaining hydroxyl groups in the partially-etherized intermediate to a pendent ester group.