(E)-1-(4-hexyloxyphenyl)-3-(4-hydroxyphenyl)-prop-2-en-1-one | 396719-67-8

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 直链 1,3-二芳基丙烷
• 英文名称: (E)-1-(4-hexyloxyphenyl)-3-(4-hydroxyphenyl)-prop-2-en-1-one
• 英文别名: (E)-1-[4-(hexyloxy)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one；(E)-1-(4-hexoxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one
• CAS: 396719-67-8
• 化学式: C₂₁H₂₄O₃
• 分子量: 324.42
• InChiKey: RKLCQYQNAHGRMK-OVCLIPMQSA-N

物化性质

• 沸点：
  495.0±45.0 °C(Predicted)
• 密度：
  1.100±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  24
• 可旋转键数：
  9
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  溴己烷 在 四丁基碘化铵 、 potassium carbonate 、 potassium hydroxide 作用下， 以 甲醇 、 丁酮 为溶剂， 反应 20.0h， 生成 (E)-1-(4-hexyloxyphenyl)-3-(4-hydroxyphenyl)-prop-2-en-1-one
  参考文献：
  名称：

  Synthesis and antimicrobial studies of hydroxylated chalcone derivatives with variable chain length

  摘要：

  A series of (E)-1-(4-alkyloxyphenyl)-3-(hydroxyphenyl)-prop-2-en-1-one have been successfully synthesised via Claisen-Schmidt condensation. The synthesised chalcone derivatives consisted of hydroxyl groups at either ortho, meta or para position and differed in the length of the alkyl groups, CnH2n+1, where n = 6, 10, 12 and 14. The structures of all compounds were defined by elemental analysis, IR, H-1- and C-13-NMR. The antimicrobial studies were carried out against wild-type Escherichia coli American Type Culture Collection 8739 to evaluate the effect of the hydroxyl and the alkyl groups of the synthesised chalcones. All the synthesised compounds have shown significant antimicrobial activities. The optimum inhibition was dependent on the position of the hydroxyl group as well as the length of the alkyl chains.

  DOI：

  10.1080/14786419.2010.502896

文献信息

• COMPOUND HAVING PHOTOSENSITIVITY, POLYMER FORMED BY POLYMERIZING THE COMPOUND, AND PRODUCTION METHOD THEREOF
  申请人：Suh Dong Hack

  公开号：US20130188120A1

  公开（公告）日：2013-07-25

  The present invention relates to a light-sensitive compound, a polymer formed by using the compound, and a production method of the compound and polymer. More particularly, the present invention relates to a unit compound that exhibits light-sensitivity with respect to three different wavelengths, a polymer having light-sensitive, which is polymerized by using the unit compound as a monomer, and a production method of the compound and polymer. The light-sensitive compound and the polymer according to the present invention may be usefully applied to an optical film.
• US9158134B2
  申请人：——

  公开号：US9158134B2

  公开（公告）日：2015-10-13
• [EN] COMPOUND HAVING PHOTOSENSITIVITY, POLYMER FORMED BY POLYMERIZING THE COMPOUND, AND PRODUCTION METHOD THEREOF<br/>[FR] COMPOSÉ PHOTOSENSIBLE, POLYMÈRE FORMÉ PAR POLYMÉRISATION DU COMPOSÉ, ET PROCÉDÉ DE FABRICATION ASSOCIÉ
  申请人：IUCF HYU

  公开号：WO2012002590A1

  公开（公告）日：2012-01-05

  본 발명은 광감성 특성을 화합물과 상기 화합물에 의하여 형성된 고분자(polymer) 및 이들의 제조방법에 대한 것이다. 보다 상세하게는, 본 발명은 3가지 서로 다른 파장에 대하여 감광성을 나타내는 단위 화합물, 상기 단위 화합물을 모노머로 하여 중합된 감광성을 갖는 고분자 및 이들의 제조방법에 대한 것이다. 본 발명에 의한 상기 감광성 화합물 및 고분자는 광학 필름에 유용하게 적용 가능하다.
• Synthesis and antimicrobial studies of hydroxylated chalcone derivatives with variable chain length
  作者：Zainab Ngaini、Siti M. Haris Fadzillah、Hasnain Hussain

  DOI：10.1080/14786419.2010.502896

  日期：2012.5

  A series of (E)-1-(4-alkyloxyphenyl)-3-(hydroxyphenyl)-prop-2-en-1-one have been successfully synthesised via Claisen-Schmidt condensation. The synthesised chalcone derivatives consisted of hydroxyl groups at either ortho, meta or para position and differed in the length of the alkyl groups, CnH2n+1, where n = 6, 10, 12 and 14. The structures of all compounds were defined by elemental analysis, IR, H-1- and C-13-NMR. The antimicrobial studies were carried out against wild-type Escherichia coli American Type Culture Collection 8739 to evaluate the effect of the hydroxyl and the alkyl groups of the synthesised chalcones. All the synthesised compounds have shown significant antimicrobial activities. The optimum inhibition was dependent on the position of the hydroxyl group as well as the length of the alkyl chains.