4-氯-7-甲基-2,3-二氢-1H-茚 | 2216-63-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 茚满类
• 中文名称: 4-氯-7-甲基-2,3-二氢-1H-茚
• 英文名称: 4-chloro-7-methyl-indan
• 英文别名: 4-Chlor-7-methyl-indan；4-Chloro-7-methylindan；4-chloro-7-methyl-2,3-dihydro-1H-indene
• CAS: 2216-63-9
• 化学式: C₁₀H₁₁Cl
• 分子量: 166.65
• InChiKey: NTFHYNQQJUEULI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

安全信息

• 海关编码：
  2903999090

反应信息

• 作为反应物：
  描述：

  4-氯-7-甲基-2,3-二氢-1H-茚 、 alkaline earth salt of/the/ methylsulfuric acid 生成 2,3-二氢-7-甲基-1H-茚-4-甲腈
  参考文献：
  名称：

  An Improved Method for the Synthetic Preparation of Methylcholanthrene

  摘要：

  DOI：

  10.1021/ja01303a037
• 作为产物：
  描述：

  对氯甲苯 在 盐酸 、 二硫化碳 、 三氯化铝 、 amalgamated zinc 作用下， 生成 4-氯-7-甲基-2,3-二氢-1H-茚
  参考文献：
  名称：

  An Improved Method for the Synthetic Preparation of Methylcholanthrene

  摘要：

  DOI：

  10.1021/ja01303a037

文献信息

• [EN] DECAHYDROQUINOXALINE DERIVATIVES AND ANALOGS THEREOF<br/>[FR] DÉRIVÉS DE DÉCAHYDROQUINOXALINE ET LEURS ANALOGUES
  申请人：OTSUKA PHARMA CO LTD

  公开号：WO2013137479A1

  公开（公告）日：2013-09-19

  A heterocyclic compound represented by the general formula (1) or a salt thereof: wherein m, l, and n respectively represent an integer of 1 or 2; X represents -O- or -CH2-; R1 represents hydrogen, a lower alkyl group, a hydroxy-lower alkyl group, a protecting group, or a tri-lower alkylsilyloxy-lower alkyl group; R2 and R3, which are the same or different, each independently represent hydrogen or a lower alkyl group; or R2 and R3 are bonded to form a cyclo-C3-C8 alkyl group; and R4 represents an aromatic group or a heterocyclic group, wherein the aromatic or heterocyclic group may have one or more arbitrary substituent(s).

  通用式（1）表示的杂环化合物或其盐：其中m，l和n分别表示1或2的整数；X表示-O-或-CH2-；R1表示氢，较低的烷基基团，羟基较低的烷基基团，保护基或三较低烷氧基较低的烷基基团；R2和R3，相同或不同，各自独立地表示氢或较低的烷基基团；或R2和R3结合形成环-C3-C8烷基基团；R4表示芳香基团或杂环基团，其中芳香基团或杂环基团可能具有一个或多个任意取代基。
• [EN] HETEROCYCLIC COMPOUNDS FOR TREATING OR PREVENTING DISORDERS CAUSED BY REDUCED NEUROTRANSMISSION OF SEROTONIN, NOREPHNEPHRINE OR DOPAMINE.<br/>[FR] COMPOSÉS HÉTÉROCYCLIQUES POUR LE TRAITEMENT OU LA PRÉVENTION DE TROUBLES PROVOQUÉS PAR UNE NEUROTRANSMISSION RÉDUITE DE LA SÉROTONINE, DE LA NORÉPINEPHRINE OU DE LA DOPAMINE
  申请人：OTSUKA PHARMA CO LTD

  公开号：WO2012036253A1

  公开（公告）日：2012-03-22

  A heterocyclic compound represented by the general formula (1) or a salt thereof: wherein m, l, and n respectively represent an integer of 1 or 2; X represents -O- or -CH2-; R1 represents hydrogen, a lower alkyl group, a hydroxy-lower alkyl group, a protecting group, or a tri-lower alkylsilyloxy-lower alkyl group; R2 and R3, which are the same or different, each independently represent hydrogen or a lower alkyl group; or R2 and R3 are bonded to form a cyclo-C3-C8 alkyl group; and R4 represents an aromatic group or a heterocyclic group, wherein the aromatic or heterocyclic group may have one or more arbitrary substituent(s).

  通用式（1）表示的杂环化合物或其盐：其中m、l和n分别表示1或2的整数；X表示-O-或-CH2-；R1表示氢、较低的烷基基团、羟基较低的烷基基团、保护基或三较低烷氧基较低的烷基基团；R2和R3，相同或不同，各自独立地表示氢或较低的烷基基团；或R2和R3结合形成环-C3-C8烷基基团；R4表示芳香基团或杂环基团，其中芳香基团或杂环基团可能具有一个或多个任意取代基。
• Le Women's Lib: Made in France
  作者：Judith Ezekiel

  DOI：10.1177/1350506802009003379

  日期：2002.8

  This article traces the French construction and demonization of American feminism (Le Women's Lib) by a segment of the women's movement and by public left-wing intellectuals. The joining of anti-American and anti-feminist traditions produces a new entity, dubbed French anti-amér-féminisme. The development is traced in the writings of one women's group, Psychanalyse et Politique, and in the debates around a so-called political correctness (PC). Defending the image of a France distinguished by harmonious gender rapport and relations of seduction, this entity is used as a mechanism to encourage French women to reject feminism or to define a different, homegrown heterosocial version. Using the examples of debates in women's studies, parity democracy and sexual harassment, the author demonstrates how anti-amér-féminisme has had material repercussions on French women's lives, such as limiting the scope of sexual harassment law.

  本文追踪了法国对美国女性主义（女权主义）的建构和妖魔化，这是由一部分女性运动和左翼知识分子共同完成的。反美和反女权主义传统的结合产生了一个新实体，被称为法国反美-女权主义。这一发展在一个名为“心理分析与政治”的妇女团体的著作中得以追踪，并在所谓的政治正确性（PC）的争论中得以体现。捍卫法国以和谐性别关系和诱惑关系为特色的形象，这一实体被用作一种机制，鼓励法国妇女拒绝女权主义或定义一种不同的、本土的异性社会版本。作者通过妇女研究、平等民主和性骚扰的争论为例，展示了反美-女权主义如何对法国妇女的生活产生了实质性影响，如限制了性骚扰法的适用范围。
• HETEROCYCLIC COMPOUNDS FOR TREATING OR PREVENTING DISORDERS CAUSED BY REDUCED NEUROTRANSMISSION OF SEROTONIN, NOREPHNEPHRINE OR DOPAMINE
  申请人：Ito Nobuaki

  公开号：US20130261081A1

  公开（公告）日：2013-10-03

  A heterocyclic compound represented by the general formula (1) or a salt thereof: wherein m, l, and n respectively represent an integer of 1 or 2; X represents —O— or —CH 2 —; R 1 represents hydrogen, a lower alkyl group, a hydroxy-lower alkyl group, a protecting group, or a tri-lower alkylsilyloxy-lower alkyl group; R 2 and R 3 , which are the same or different, each independently represent hydrogen or a lower alkyl group; or R 2 and R 3 are bonded to form a cyclo-C3-C8 alkyl group; and R 4 represents an aromatic group or a heterocyclic group, wherein the aromatic or heterocyclic group may have one or more arbitrary substituent(s).

  一种由通式（1）表示的杂环化合物或其盐： 其中，m、l和n分别表示1或2的整数；X表示-O-或-CH2-；R1表示氢、低碳基、羟基-低碳基、保护基或三-低硅氧基-低碳基；R2和R3分别独立地表示氢或低碳基；或者R2和R3结合形成环状C3-C8烷基；R4表示芳基或杂环基，其中芳基或杂环基可能具有一个或多个任意取代基。
• Methods of treating anxiety by administering a substituted quinolone
  申请人：OTSUKA PHARMACEUTICAL CO., LTD.

  公开号：US11273168B2

  公开（公告）日：2022-03-15

  A heterocyclic compound represented by the general formula (1) or a salt thereof: wherein m, l, and n respectively represent an integer of 1 or 2; X represents —O— or —CH2—; R1 represents hydrogen, a lower alkyl group, a hydroxy-lower alkyl group, a protecting group, or a tri-lower alkylsilyloxy-lower alkyl group; R2 and R3, which are the same or different, each independently represent hydrogen or a lower alkyl group; or R2 and R3 are bonded to form a cyclo-C3-C8 alkyl group; and R4 represents an aromatic group or a heterocyclic group, wherein the aromatic or heterocyclic group may have one or more arbitrary substituent(s).

  由通式(1)代表的杂环化合物或其盐： 其中 m、l 和 n 分别代表 1 或 2 的整数；X 代表 -O- 或 -CH2-；R1 代表氢、低级烷基、羟基-低级烷基、保护基或三低级烷基硅氧基-低级烷基； R2 和 R3（相同或不同）各自独立地代表氢或低级烷基；或 R2 和 R3 键合形成环-C3-C8 烷基；以及 R4 代表芳香基团或杂环基团，其中芳香基团或杂环基团可具有一个或多个任意取代基。