4-(5-phenyl-oxazol-2-yl)-pyridine 1-oxide | 105975-13-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 4-(5-phenyl-oxazol-2-yl)-pyridine 1-oxide
• 英文别名: 4-<5-phenyl-oxazolyl-(2)>-pyridin-N-oxyd
• CAS: 105975-13-1
• 化学式: C₁₄H₁₀N₂O₂
• 分子量: 238.246
• InChiKey: UAJHRUKYCUDDQI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.64
• 重原子数：
  18.0
• 可旋转键数：
  2.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  52.97
• 氢给体数：
  0.0
• 氢受体数：
  3.0

反应信息

• 作为产物：
  描述：

  在 硫酸 作用下， 生成 4-(5-phenyl-oxazol-2-yl)-pyridine 1-oxide
  参考文献：
  名称：

  Combinatorial discovery of novel fluorescent dyes based on Dapoxyl™

  摘要：

  We have developed a combinatorial method for the fast and effective synthesis of a library based on a known fluorescent dye, Dapoxyl(TM) using parallel solution-phase chemistry. By screening the 140 new compounds using fluorescence-based assays, we identified three new fluorescent dyes with novel properties. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(02)00999-1

文献信息

• Quaternary Salt Formation of Substituted Oxazoles and Thiazoles¹
  作者：Vernon N. Kerr、Donald G. Ott、F. Newton Hayes

  DOI：10.1021/ja01486a042

  日期：1960.1

  The course of quaternization of a number of oxazoles and thiazoles and various dimethylaminophenyl, pyridyl, and quinolyl derivatives was investigated. The salts were screened for hypotensive activity. (auth)

  研究了许多恶唑和噻唑以及各种二甲氨基苯基、吡啶基和喹啉衍生物的季铵化过程。筛选盐的低血压活性。（授权）