2-methoxy-3-phenylpropanol | 221908-50-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-methoxy-3-phenylpropanol
• 英文别名: 2-Methoxy-3-phenylpropan-1-ol
• CAS: 221908-50-5
• 化学式: C₁₀H₁₄O₂
• 分子量: 166.22
• InChiKey: BNCXGTPWJTZUHD-UHFFFAOYSA-N

物化性质

• 沸点：
  273.1±20.0 °C(Predicted)
• 密度：
  1.042±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-methoxy-3-phenylpropanol 在 草酰氯 、 二甲基亚砜 、 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 0.67h， 以90%的产率得到2-methoxy-3-phenylpropanal
  参考文献：
  名称：

  Almond oxynitrilase-catalyzed transformation of aldehydes is strongly influenced by naphthyl and alkoxy substituents

  摘要：

  Different alpha- and beta-substituted aldehydes have been submitted to the catalytic action of almond oxynitrilase (PaHNL), in order to explore the influence of a stereocenter already present in the substrate on the selectivity of this enzyme.(1) The results indicate that naphthyl and alkoxy substituents in the alpha- and also in the beta-position to the aldehyde group significantly influence the stereochemical outcome of the PaHNL-catalyzed transformation. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0957-4166(99)00427-9
• 作为产物：
  描述：

  (2-Methoxy-3-phenylpropyl) acetate 在 水 、 scandium tris(trifluoromethanesulfonate) 作用下， 以 甲醇 为溶剂， 反应 18.0h， 以99%的产率得到2-methoxy-3-phenylpropanol
  参考文献：
  名称：

  Scandium trifluoromethanesulfonate-catalyzed mild, efficient, and selective cleavage of acetates bearing a coordinative group

  摘要：

  Scandium trifluoromethanesulfonate is a useful Lewis acid catalyst for cleavage of acetates containing coordinative groups adjacent to the acetyl carbonyl. The reaction proceeds under weak acidic conditions at room temperature. Racemizable alpha-keto acyloxy compounds are deacetylated without racemization. Selective mono-deacetylation at the 10-position of paclitaxel has been achieved. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(99)00003-9

文献信息

• Graphene oxide as an acid catalyst for the room temperature ring opening of epoxides
  作者：Amarajothi Dhakshinamoorthy、Mercedes Alvaro、Patricia Concepción、Vicente Fornés、Hermenegildo Garcia

  DOI：10.1039/c2cc31385e

  日期：——

  The minute amount of hydrogen sulfate groups introduced into the graphene oxide (GO) obtained by Hummers oxidation of graphite renders this material as a highly efficient, recyclable acid catalyst for the ring opening of epoxides with methanol and other primary alcohols as nucleophile and solvent.

  通过石墨的Hummers氧化获得的引入氧化石墨烯（GO）中的微量硫酸氢基团使该材料成为高效的可循环酸催化剂，用于与甲醇和其他伯醇（作为亲核试剂和溶剂）一起使环氧化物开环。
• Enhancement of CO₂ Adsorption and Catalytic Properties by Fe-Doping of [Ga₂(OH)₂(L)] (H₄L = Biphenyl-3,3′,5,5′-tetracarboxylic Acid), MFM-300(Ga₂)
  作者：Cristina P. Krap、Ruth Newby、Amarajothi Dhakshinamoorthy、Hermenegildo García、Izabela Cebula、Timothy L. Easun、Mathew Savage、Jennifer E. Eyley、Shan Gao、Alexander J. Blake、William Lewis、Peter H. Beton、Mark R. Warren、David R. Allan、Mark D. Frogley、Chiu C. Tang、Gianfelice Cinque、Sihai Yang、Martin Schröder

  DOI：10.1021/acs.inorgchem.5b02108

  日期：2016.2.1

  [Fe3O1.5(OH)(HL)(L)0.5(H2O)3.5], MFM-310(Fe), was synthesized with Fe(NO3)3 and the same ligand via hydrothermal methods. [MFM-310(Fe)] crystallizes in the orthorhombic space group Pmn21 with a = 10.560(4) Å, b = 19.451(8) Å, and c = 11.773(5) Å and incorporates μ3-oxo-centered trinuclear iron cluster nodes connected by ligands to give a 3D nonporous framework that has a different structure to the MFM-300

  金属有机骨架（MOF）通常是使用单一类型的金属离子合成的，而含有不同金属离子混合物的MOF引起了人们的极大兴趣，它们代表了一种增强和调整材料特性的方法。我们报告了[Ga 2（OH）2（L）]（H 4 L =联苯-3,3'，5,5'-四羧酸）的合成，命名为MFM-300（Ga 2），（MFM =通过在DMF，THF和含HCl的混合物中将Ga（NO 3）3和H 4 L进行溶剂热反应3天，以曼彻斯特框架材料代替NOTT名称。MFM-300（Ga 2）在四方空间群I 4 1中结晶在图22中，a = b = 15.0174（7）Å和c = 11.9111（11）Å，并且与Al（III）类似物MFM-300（Al 2）具有同构结构，其孔用-OH基桥接Ga（III）中心修饰。可以通过与均相混合物反应，在与MFM-300（Ga 2）类似的条件下制备等结构的Fe掺杂材料[Ga 1.87 Fe 0.13（OH）2（L）]
• Metallized mesoporous silicate and method of oxidation with the same
  申请人：Hagiya Koji

  公开号：US20050090688A1

  公开（公告）日：2005-04-28

  A metallized mesoporous silicate which is obtained by (i) reacting (a) either a metal peroxide obtained by the reaction of an aqueous hydrogen peroxide solution with at least one metal or metal compound selected from the group consisting of the following 1) to 4) 1) tungsten 2) molybdenum 3) vanadium 4) compounds comprising 4 a ) any of tungsten, molybdenum, and vanadium and 4 b ) at least one element selected from Groups 13 to 16 (excluding oxygen) or a solution of the metal peroxide with (b) a silicon compound in the presence of an alkylamine or a quaternary ammonium salt and separating the resultant silicate; and a process for producing the metallized mesoporous silicate. Also provided is a method of organic synthesis with the silicate.

  一种金属化介孔硅酸盐，其通过以下步骤获得：(i)在烷基胺或季铵盐存在下，将(a)氢氧化物和至少选择自以下1)至4)中的一种金属或金属化合物反应得到的金属过氧化物1)钨2)钼3)钒4)包含4a)钨、钼和钒和4b)至少选择自第13至16组(不包括氧)的元素的化合物或金属过氧化物的溶液与(b)硅化合物反应，并分离所得的硅酸盐；以及生产金属化介孔硅酸盐的方法。同时提供一种使用该硅酸盐进行有机合成的方法。
• METALLIZED MESOPOROUS SILICATE AND METHOD OF OXIDATION WITH THE SAME
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP1473275A1

  公开（公告）日：2004-11-03

  A metallized mesoporous silicate which is obtained by (i) reacting (a) either a metal peroxide obtained by the reaction of an aqueous hydrogen peroxide solution with at least one metal or metal compound selected from the group consisting of the following 1) to 4) 1) tungsten 2) molybdenum 3) vanadium 4) compounds comprising 4a) any of tungsten, molybdenum, and vanadium and 4b) at least one element selected from Groups 13 to 16 (excluding oxygen) or a solution of the metal peroxide with (b) a silicon compound in the presence of an alkylamine or a quaternary ammonium salt and separating the resultant silicate; and a process for producing the metallized mesoporous silicate. Also provided is a method of organic synthesis with the silicate.

  一种金属化介孔硅酸盐，它是通过(i)使(a)过氧化氢水溶液与至少一种选自以下组别的金属或金属化合物反应而得到的过氧化金属1)至4)1)钨2)钼3)钒4)包括4a)钨、钼和钒中的任何一种和4b)至少一种选自第13至16组的元素(不包括氧)的化合物或过氧化金属的溶液与(b)硅化合物反应而得到的、钼和钒以及 4b) 至少一种选自第 13 组至第 16 组的元素（不包括氧）的化合物，或在烷基胺或季铵盐存在下，过氧化金属与 (b) 硅化合物的溶液，并分离得到的硅酸盐；以及生产金属化介孔硅酸盐的工艺。此外，还提供了一种用硅酸盐进行有机合成的方法。
• 4,8-DIMETHYL-7-NONEN-2-ON UND 4,8-DIMETHYLNONAN-2-ON ALS RIECHSTOFFE
  申请人：Symrise GmbH & Co. KG

  公开号：EP1682230A1

  公开（公告）日：2006-07-26