Trimethyl-((E)-4-phenylsulfanyl-but-3-en-1-ynyl)-silane | 161944-19-0

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: Trimethyl-((E)-4-phenylsulfanyl-but-3-en-1-ynyl)-silane
• 英文别名: trimethyl-[(E)-4-phenylsulfanylbut-3-en-1-ynyl]silane
• CAS: 161944-19-0
• 化学式: C₁₃H₁₆SSi
• 分子量: 232.422
• InChiKey: ZCWXCZBIJCTDEQ-YRNVUSSQSA-N

物化性质

• 沸点：
  288.8±23.0 °C(predicted)
• 密度：
  1.00±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.17
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  25.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  Trimethyl-((E)-4-phenylsulfanyl-but-3-en-1-ynyl)-silane 在 1,2-双(二苯基膦)乙烷氯化镍 potassium fluoride 、 N-溴代丁二酰亚胺(NBS) 、 Schwartz's reagent 作用下， 以 四氢呋喃 、 甲醇 为溶剂， 反应 1.8h， 生成 2-((1E,3E)-4-Phenylsulfanyl-buta-1,3-dienyl)-thiophene
  参考文献：
  名称：

  A general approach to conjugated (E,E)-dienes through sequential coupling reactions

  摘要：

  a straightforward and useful procedure leading to a variety of conjugated (E,E)-dienes is reported. The method is based upon sequential coupling reactions of Grignard reagents with the readily available (1E,3E)1l-bromo-4-phenylthio-1,3-butadiene in the presence of NiCl2(dppe).

  DOI：

  10.1016/s0040-4039(00)78514-5
• 作为产物：
  描述：

  (E)-2-chlorovinylthiobenzene 、 magnesium,ethynyl(trimethyl)silane,bromide 在 1,2-双(二苯基膦)乙烷氯化镍 作用下， 以 四氢呋喃 为溶剂， 反应 1.0h， 以70%的产率得到Trimethyl-((E)-4-phenylsulfanyl-but-3-en-1-ynyl)-silane
  参考文献：
  名称：

  A general approach to conjugated (E,E)-dienes through sequential coupling reactions

  摘要：

  a straightforward and useful procedure leading to a variety of conjugated (E,E)-dienes is reported. The method is based upon sequential coupling reactions of Grignard reagents with the readily available (1E,3E)1l-bromo-4-phenylthio-1,3-butadiene in the presence of NiCl2(dppe).

  DOI：

  10.1016/s0040-4039(00)78514-5

文献信息

• A straightforward synthesis of symmetrical polyendiynes by dimerization reactions of silyl derivatives
  作者：Francesco Babudri、Vito Fiandanese、Giuseppe Marchese、Angela Punzi

  DOI：10.1016/s0022-328x(98)00724-4

  日期：1998.9

  A straightforward synthesis of polyendiynes is described. The method is based upon a simple dimerization reaction of silylated enynes in the presence of copper salts. A variety of polyunsaturated compounds have been obtained in high yields and with high retention of configuration. (C) 1998 Elsevier Science S.A. All rights reserved.
• A general approach to conjugated (E,E)-dienes through sequential coupling reactions
  作者：Francesco Babudri、Vito Fiandanese、Luigia Mazzone、Francesco Naso

  DOI：10.1016/s0040-4039(00)78514-5

  日期：1994.11

  a straightforward and useful procedure leading to a variety of conjugated (E,E)-dienes is reported. The method is based upon sequential coupling reactions of Grignard reagents with the readily available (1E,3E)1l-bromo-4-phenylthio-1,3-butadiene in the presence of NiCl2(dppe).