2,7-dibromo-octanedioic acid | 3479-82-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2,7-dibromo-octanedioic acid
• 英文别名: 2,7-Dibrom-octandisaeure；meso-α,α'-Dibrom-korksaeure；α,α'-Dibrom-korksaeure；2,7-Dibromooctanedioic acid
• CAS: 3479-82-1
• 化学式: C₈H₁₂Br₂O₄
• 分子量: 331.989
• InChiKey: DWXFXWYNVJXVQQ-UHFFFAOYSA-N

物化性质

• 熔点：
  120 °C(Solv: benzene (71-43-2); ethanol (64-17-5))
• 沸点：
  423.8±45.0 °C(Predicted)
• 密度：
  1.876±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  14
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

安全信息

• 海关编码：
  2917190090

反应信息

• 作为反应物：
  描述：

  2,7-dibromo-octanedioic acid 在 溴 、 碘 作用下， 生成 2,2,7,7-tetrabromo-octanedioic acid
  参考文献：
  名称：

  Treibs et al., Chemische Berichte, 1958, vol. 91, p. 290,296

  摘要：

  DOI：
• 作为产物：
  描述：

  2-辛烯二酸 在 sodium amalgam 、 氯化亚砜 、 水 、 溴 作用下， 生成 2,7-dibromo-octanedioic acid
  参考文献：
  名称：

  Goss; Ingold, Journal of the Chemical Society, 1926, p. 1474

  摘要：

  DOI：

文献信息

• Diarylamino group-containing copolymer, organic electroluminescent device, and method of producing hole transport layer for organic electroluminescent device
  申请人：Kato Shinji

  公开号：US20050008893A1

  公开（公告）日：2005-01-13

  An organic electroluminescent device is provided which has a high degree of adhesion between an anode and a hole transport layer, the device emitting light of high luminance even when driven by low applied voltages. Copolymers useful in hole transport layers in organic electroluminescent devices are also provided. Methods of producing hole transport layers for organic electroluminescent devices which can emit light of high luminance even when driven by low applied voltages are also provided, the hole transport layers having high degrees of adhesion with anode. A copolymer comprises a monomer unit including in its structure an electron-donating N,N-diaryl-substituted amino group such as an N,N-diphenylaminophenyl group, or a group having an N,N-diaryl-substituted amino moiety, and a monomer unit having at least one functional group. Also, a hole transport layer, which has excellent thickness accuracy, has an extremely smooth surface, and is very thin, can be formed of this copolymer or a copolymer having the same hole transport functional group. An organic electroluminescent device, which emits light of high luminance even when driven by low applied voltages, can be obtained by using this hole transport layer.

  提供了一种有机电致发光器件，其阳极和空穴传输层之间具有高度的粘附性，即使在低电压驱动下也能发出高亮度的光。还提供了在有机电致发光器件中用于空穴传输层的共聚物。还提供了制备空穴传输层的方法，该方法可以在低电压驱动下发出高亮度的光，空穴传输层与阳极具有高度的粘附性。共聚物包括一个单体单元，其结构中包括一个电子给体的N，N-二芳基取代氨基，例如N，N-二苯基氨基苯基基团，或具有N，N-二芳基取代氨基基团的基团，以及至少具有一个功能基团的单体单元。此共聚物或具有相同空穴传输功能基团的共聚物可以形成具有优异厚度精度、极其光滑表面且非常薄的空穴传输层。通过使用此空穴传输层，可以获得发出高亮度光的有机电致发光器件，即使在低电压驱动下也能发光。
• NOVEL 8,10-DIAZA-BICYCLO[4.3.1]DECANE DERIVATIVES AND THEIR MEDICAL USE
  申请人：Peters Dan

  公开号：US20090099153A1

  公开（公告）日：2009-04-16

  This invention relates to novel 8,10-diaza-bicyclo[4.3.1]decane derivatives, which are found to be cholinergic ligands at the nicotinic acetylcholine receptors. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.

  本发明涉及一种新型的8,10-二氮杂双环[4.3.1]十碳烷衍生物，发现它们是尼古丁酸乙酰胆碱受体的胆碱能配体。由于它们的药理特性，本发明的化合物可能对治疗与中枢神经系统（CNS）和外周神经系统（PNS）的胆碱能系统相关的疾病或疾病有关的平滑肌收缩、内分泌疾病或疾病、神经退行性疾病或疾病、炎症、疼痛和化学物质滥用终止引起的戒断症状等多种不同的疾病或疾病具有用处。
• Neuberg; Neimann, Hoppe-Seyler's Zeitschrift fur Physiologische Chemie, 1905, vol. 45, p. 120
  作者：Neuberg、Neimann

  DOI：——

  日期：——
• Ouchi, Yakugaku Zasshi/Journal of the Pharmaceutical Society of Japan, 1952, vol. 72, p. 437
  作者：Ouchi

  DOI：——

  日期：——
• Gantter; Hell, Chemische Berichte, 1882, vol. 15, p. 145
  作者：Gantter、Hell

  DOI：——

  日期：——