| 207727-06-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• CAS: 207727-06-8
• 化学式: C₄₉H₄₂N₄Zn
• 分子量: 752.289
• InChiKey: JZNCJXFCCOVANV-CAJDOLSKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  [5-iodo-10,15,20-trimesitylporphyrinato]zinc(II) 、 在 bis-triphenylphosphine-palladium(II) chloride 、 copper(l) iodide 、 三乙胺 作用下， 以 甲苯 为溶剂， 反应 18.0h， 以27 mg的产率得到ethynyl-linked porphyrin dimer
  参考文献：
  名称：

  An easy one-pot desilylation/copper-free Sonogashira cross-coupling reaction assisted by tetra-butylammonium fluoride (TBAF): synthesis of highly π-conjugated porphyrins

  摘要：

  Sonogashira cross-coupling is a key reaction for the synthesis of highly conjugated oligomers. However, its application has well known drawbacks; it requires drastic inert atmosphere conditions, generates homocoupling by-product of the terminal alkyne and others. In this paper, we describe a new and easy procedure using PdCl2(PPh3)(2) as catalyst assisted by TBAF in a one-pot desilylation/copper-free Sonogashira reaction for the synthesis of highly conjugated porphyrin oligomers. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2013.04.092
• 作为产物：
  描述：

  5,10,15-trimesitylporphyrin 在 bis-triphenylphosphine-palladium(II) chloride 、 copper(l) iodide 、 四丁基氟化铵 、 碘 、 三乙胺 、 [双(三氟乙酰氧基)碘]苯 作用下， 以 四氢呋喃 、 甲醇 、 氯仿 、 甲苯 为溶剂， 反应 8.5h， 生成
  参考文献：
  名称：

  An easy one-pot desilylation/copper-free Sonogashira cross-coupling reaction assisted by tetra-butylammonium fluoride (TBAF): synthesis of highly π-conjugated porphyrins

  摘要：

  Sonogashira cross-coupling is a key reaction for the synthesis of highly conjugated oligomers. However, its application has well known drawbacks; it requires drastic inert atmosphere conditions, generates homocoupling by-product of the terminal alkyne and others. In this paper, we describe a new and easy procedure using PdCl2(PPh3)(2) as catalyst assisted by TBAF in a one-pot desilylation/copper-free Sonogashira reaction for the synthesis of highly conjugated porphyrin oligomers. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2013.04.092