2-Phenyl-4-methylideneoxazol-5-one | 90448-12-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-Phenyl-4-methylideneoxazol-5-one
• 英文别名: 4-methylene-2-phenyloxazol-5(4H)-one；4-methylene-2-phenyl-4H-oxazol-5-one；4-Methylen-2-phenyl-4H-oxazol-5-on；4-Methylidene-2-phenyl-1,3-oxazol-5-one
• CAS: 90448-12-7
• 化学式: C₁₀H₇NO₂
• 分子量: 173.171
• InChiKey: QMVDSTMRMBTHIF-UHFFFAOYSA-N

物化性质

• 沸点：
  261.9±23.0 °C(Predicted)
• 密度：
  1.20±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  38.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  重氮甲烷 、 2-Phenyl-4-methylideneoxazol-5-one 以 氯仿 为溶剂， 反应 0.05h， 以58%的产率得到2-phenylspiro-5-one
  参考文献：
  名称：

  具有增强反应活性的难以捉摸的脱氢丙氨酸衍生物。

  摘要：

  首次提出了一种简单的方法，用于化学合成和使用来自丝氨酸的高反应性4-甲烯恶唑-5（4H）-酮。这些脱氢丙氨酸衍生物类似于裂解酶和氨基变位酶中存在的天然4-甲叉基咪唑-5-酮（MIO）辅助因子，在以下条件下会与碳亲核试剂（如甲硅烷基烯醇醚）快速反应，并与重氮化合物和反应性二烯进行环加成反应。在非常温和的条件下，无需任何金属催化剂或环应变活化，因此具有生物共轭的潜力。

  DOI：

  10.1002/cbic.201800758
• 作为产物：
  描述：

  N-benzoyl-O-benzyl-DL-serine 在 N,N'-二异丙基碳二亚胺 作用下， 以 氯仿 为溶剂， 反应 0.25h， 以90%的产率得到2-Phenyl-4-methylideneoxazol-5-one
  参考文献：
  名称：

  具有增强反应活性的难以捉摸的脱氢丙氨酸衍生物。

  摘要：

  首次提出了一种简单的方法，用于化学合成和使用来自丝氨酸的高反应性4-甲烯恶唑-5（4H）-酮。这些脱氢丙氨酸衍生物类似于裂解酶和氨基变位酶中存在的天然4-甲叉基咪唑-5-酮（MIO）辅助因子，在以下条件下会与碳亲核试剂（如甲硅烷基烯醇醚）快速反应，并与重氮化合物和反应性二烯进行环加成反应。在非常温和的条件下，无需任何金属催化剂或环应变活化，因此具有生物共轭的潜力。

  DOI：

  10.1002/cbic.201800758

文献信息

• Photoelectric conversion material, film containing the material, photoelectric conversion device, production method thereof, photosensor, imaging device and their use methods
  申请人：Fujifilm Corporation

  公开号：EP2292586A2

  公开（公告）日：2011-03-09

  A compound represented by the following formula (I), and a photoelectric conversion device containing the compound: wherein Z1 is a ring containing two carbon atoms and represents a 5-membered ring, a 6-membered ring or a condensed ring containing at least either a 5-membered ring or a 6-membered ring, each of L1, L2 and L3 independently represents an unsubstituted methane group or a substituted methine group, n represents an integer of 0 or more, each of R1, R2, R3, R4, R5 and R6 independently represents a hydrogen atom or a substituent, R1 and R2, R2 and R3, R4 and R5, or R5 and R6 may be combined with each other to form a ring, and each of R21 and R22 independently represents a substituted aryl group, an unsubstituted aryl group, a substituted heteroaryl group or an unsubstituted heteroaryl group, provided that the case where both R21 and R22 are an unsubstituted phenyl group is excluded.

  下式 (I) 所代表的化合物，以及含有该化合物的光电转换装置： 其中 Z1 是含有两个碳原子的环，代表 5 元环、6 元环或至少含有一个 5 元环或一个 6 元环的缩合环，L1、L2 和 L3 各自独立地代表未取代的甲烷基团或取代的甲基，n 代表 0 或以上的整数，R1、R2、R3、R4、R5 和 R6 各自独立地代表氢原子或取代基、R1和R2、R2和R3、R4和R5或R5和R6可相互结合形成一个环，R21和R22各自独立地代表取代的芳基、未取代的芳基、取代的杂芳基或未取代的杂芳基，但不包括R21和R22均为未取代的苯基的情况。
• Compounds for use in a photoelectric conversion material, and intermediates for the preparation thereof
  申请人：Fujifilm Corporation

  公开号：EP2786983A1

  公开（公告）日：2014-10-08

  The invention provides a compound represented by the following formula (V): Also claimed are compounds of formula (I) which are useful as a photoelectric conversion material. The aldehydes of formula (V) are intermediates in the preparation of compounds of formula (I).

  本发明提供了由下式（V）代表的化合物： 本发明还涉及可用作光电转换材料的式 (I) 化合物。式（V）的醛是制备式（I）化合物的中间体。
• PHOTOELECTRIC CONVERSION MATERIAL, FILM CONTAINING THE MATERIAL, PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR USE METHODS
  申请人：HAMANO Mitsumasa

  公开号：US20110056562A1

  公开（公告）日：2011-03-10

  A compound represented by the following formula (I), and a photoelectric conversion device containing the compound: wherein Z 1 is a ring containing two carbon atoms and represents a 5-membered ring, a 6-membered ring or a condensed ring containing at least either a 5-membered ring or a 6-membered ring, each of L 1 , L 2 and L 3 independently represents an unsubstituted methine group or a substituted methine group, n represents an integer of 0 or more, each of R 1 , R 2 , R 3 , R 4 , R 5 and R 6 independently represents a hydrogen atom or a substituent, R 1 and R 2 , R 2 and R 3 , R 4 and R 5 , or R 5 and R 6 may be combined with each other to form a ring, and each of R 21 and R 22 independently represents a substituted aryl group, an unsubstituted aryl group, a substituted heteroaryl group or an unsubstituted heteroaryl group, provided that the case where both R 21 and R 22 are an unsubstituted phenyl group is excluded.
• PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVE METHODS
  申请人：NOMURA Kimiatsu

  公开号：US20110063485A1

  公开（公告）日：2011-03-17

  A photoelectric conversion device comprising a transparent electrically conductive film, a photoelectric conversion film and an electrically conductive film in this order, wherein the photoelectric conversion film comprises a photoelectric conversion layer, and an electron blocking layer, wherein the electron blocking layer contains a compound represented by the specific formula.
• PHOTOELECTRIC CONVERSION ELEMENT, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVING METHOD
  申请人：Fukuzaki Eiji

  公开号：US20120080585A1

  公开（公告）日：2012-04-05

  To provide a photoelectric conversion element capable of functioning as a photoelectric conversion element when a compound having a specific structure is applied to the photoelectric conversion element, causing the element to exhibit a low dark current, and reducing the range of increase in the dark current even when the element is heat-treated, and an imaging device equipped with such a photoelectric conversion element. A photoelectric conversion element having a photoelectric conversion film which is sandwiched between a transparent electrically conductive film and an electrically conductive film and contains a photoelectric conversion layer and an electron blocking layer, wherein the electron blocking layer contains a compound having, as a substituent, a substituted amino group containing three or more ring structures.