Trimethyl-[2-[[2-(3-methylbut-2-enyl)imidazol-1-yl]methoxy]ethyl]silane | 146697-86-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: Trimethyl-[2-[[2-(3-methylbut-2-enyl)imidazol-1-yl]methoxy]ethyl]silane
• CAS: 146697-86-1
• 化学式: C₁₄H₂₆N₂OSi
• 分子量: 266.459
• InChiKey: LYSALIUDGGCLBI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  18
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  27
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  Trimethyl-[2-[[2-(3-methylbut-2-enyl)imidazol-1-yl]methoxy]ethyl]silane 在 四丁基氟化铵 作用下， 生成 2-(3-Methyl-but-2-enyl)-1H-imidazole
  参考文献：
  名称：

  Allylation of imidazoles. The beneficial effect of imidazole ligands on (.pi.-allyl)nickel coupling

  摘要：

  The coupling of (pi-allyl)nickel halide complexes with iodoimidazoles proceeds efficiently in toluene solution without the use of coordinating solvent or added ligand. Nickel-promoted allylation, and symmetrical coupling, of non-imidazole aryl halides is enhanced by using N-methylimidazole as an additive.

  DOI：

  10.1021/jo00057a006
• 作为产物：
  描述：

  1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazole 在 正丁基锂 、 碘 作用下， 反应 12.25h， 生成 Trimethyl-[2-[[2-(3-methylbut-2-enyl)imidazol-1-yl]methoxy]ethyl]silane
  参考文献：
  名称：

  Allylation of imidazoles. The beneficial effect of imidazole ligands on (.pi.-allyl)nickel coupling

  摘要：

  The coupling of (pi-allyl)nickel halide complexes with iodoimidazoles proceeds efficiently in toluene solution without the use of coordinating solvent or added ligand. Nickel-promoted allylation, and symmetrical coupling, of non-imidazole aryl halides is enhanced by using N-methylimidazole as an additive.

  DOI：

  10.1021/jo00057a006

文献信息

• Allylation of imidazoles. The beneficial effect of imidazole ligands on (.pi.-allyl)nickel coupling
  作者：Spencer Knapp、Jennifer Albaneze、Harvey J. Schugar

  DOI：10.1021/jo00057a006

  日期：1993.2

  The coupling of (pi-allyl)nickel halide complexes with iodoimidazoles proceeds efficiently in toluene solution without the use of coordinating solvent or added ligand. Nickel-promoted allylation, and symmetrical coupling, of non-imidazole aryl halides is enhanced by using N-methylimidazole as an additive.