2-(2,4-dihydroxyphenyl)-4,6-bis(4-tert-butylphenyl)-1,3,5-triazine | 253158-14-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(2,4-dihydroxyphenyl)-4,6-bis(4-tert-butylphenyl)-1,3,5-triazine
• 英文别名: bis-(4-t-butylphenyl)-6-(2,4-dihydroxyphenyl)-1,3,5-triazine；2,4-bis(4-tert-butylphenyl)-6-(2,4-dihydroxyphenyl)-1,3,5-triazine；4-[4,6-bis(4-tert-butylphenyl)-1,3,5-triazin-2-yl]benzene-1,3-diol
• CAS: 253158-14-4
• 化学式: C₂₉H₃₁N₃O₂
• 分子量: 453.584
• InChiKey: NCEXPKAMRQUNDL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.6
• 重原子数：
  34
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.28
• 拓扑面积：
  79.1
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  2-(2,4-dihydroxyphenyl)-4,6-bis(4-tert-butylphenyl)-1,3,5-triazine 、 氯乙酸乙酯 在 potassium iodide 、 potassium carbonate 作用下， 以 丙酮 为溶剂， 生成 2,4-bis-(4-tert-butylphenyl)-6-(2-hydroxy-4-ethoxycarbonylmethoxyphenyl)-1,3,5-triazine
  参考文献：
  名称：

  Non-yellowing para-tertiary-alkyl phenyl substituted triazine and pyrimidine ultraviolet light absorbers

  摘要：

  这项发明涉及对抗环境力量（包括紫外线、光化辐射、氧化、湿度、大气污染物等）降解的对叔烷基苯基取代嘧啶和三嗪化合物及其用途。新的对叔烷基苯基取代嘧啶和三嗪类包括两个叔烷基化苯基团，以及连接到三嗪或嘧啶环上的间苯二酚或取代间苯二酚基团。在适当情况下，这些材料可以通过可结合功能基团与涂料、聚合物、树脂、有机化合物等配方中的材料反应而与之结合。还公开了一种通过将这种对叔烷基苯基取代嘧啶和三嗪纳入的方法来稳定材料。

  公开号：

  US06239276B1
• 作为产物：
  描述：

  2,4-双[4-(叔丁基)苯基]-6-氯-1,3,5-三嗪 、 间苯二酚 、 三氯化铝 、 在 氩 、 水 作用下， 以 氯苯 为溶剂， 反应 6.0h， 以to give 4.4 g of a product的产率得到2-(2,4-dihydroxyphenyl)-4,6-bis(4-tert-butylphenyl)-1,3,5-triazine
  参考文献：
  名称：

  Non-yellowing part-tertiary-alkyl phenyl substituted triazine and pyrimidine ultraviolet light absorbers

  摘要：

  本发明涉及对抗环境力量，包括紫外线、光化学辐射、氧化、湿度、大气污染物和其组合，以保护对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对于对

  公开号：

  US06509399B2

文献信息

• Process for making triazine UV absorbers using lewis acids and reaction promoters
  申请人：CYTEC Technologies Corp.

  公开号：US20010020094A1

  公开（公告）日：2001-09-06

  It has been now surprisingly discovered after extensive research that 2-halo-4,6-bisaryl-1,3,5-triazine can be prepared with unprecedented selectivity, efficiency, mild conditions, and in high yield by the reaction of cyanuric halide with aromatics in the presence of at least one Lewis acid and at least one reaction promoter. This reaction is also unprecedently general as a variety of aromatics can be used to produce a wide selection of 2-halo-4,6-bisaryl-1,3,5-triazines. The novel approach includes the use of the reaction promoters in combination with at least one Lewis acid under certain reaction conditions to promote the formation of 2-halo-4,6-bisaryl-1,3,5-triazine compounds from cyanuric halide. Preferably, the Lewis acids and reaction promoters are combined to form a complex. 2-Halo-4,6-bisaryl-1,3,5-triazines are key intermediates for making 2-(2-oxyaryl)-4,6-bisaryl-1,3,5-triazine class of UV absorbers.

  经过广泛的研究，令人惊讶地发现，通过氰尿酸卤化物与芳香族化合物在至少一种路易斯酸和至少一种反应促进剂的存在下反应，可以以前所未有的选择性、效率、温和条件和高产率制备2-卤代-4,6-双芳基-1,3,5-三嗪。该反应具有前所未有的广泛性，因为可以使用各种芳香族化合物来生产各种2-卤代-4,6-双芳基-1,3,5-三嗪。新的方法包括在特定反应条件下，将反应促进剂与至少一种路易斯酸结合使用，促进从氰尿酸卤化物中形成2-卤代-4,6-双芳基-1,3,5-三嗪化合物。最好将路易斯酸和反应促进剂组合形成复合物。2-卤代-4,6-双芳基-1,3,5-三嗪是制备2-(2-氧基芳基)-4,6-双芳基-1,3,5-三嗪类紫外线吸收剂的关键中间体。
• Trisaryl-1,3,5-triazine ultraviolet light absorbers containing hindered phenols
  申请人：Ciba Specialty Chemicals Corporation

  公开号：US06239275B1

  公开（公告）日：2001-05-29

  This invention relates generally to hindered phenol-substituted triazines and the use thereof to protect materials such as coatings, polymers, resins, organic compounds and the like against degradation by environmental forces, inclusive of ultraviolet light, actinic radiation, oxidation, moisture, atmospheric pollutants and combinations thereof. The new class of hindered phenol-substituted triazines includes a trisaryl-1,3,5-triazine in which one of the aryl groups is substituted by a group which comprises a hindered phenol or is a hindered phenol and is further substituted by a hydroxyl group, either free or blocked to form a latent stabilizer, ortho- to the point of attachment to the triazine. These materials may, under the appropriate circumstances, form oligomers. A method for stabilizing a material by incorporating such hindered phenol-substituted triazines is also disclosed.

  本发明涉及一种阻碍酚取代的三嗪，并将其用于保护涂层、聚合物、树脂、有机化合物等材料免受环境力量的破坏，包括紫外线、光化学辐射、氧化、湿度、大气污染物及其组合作用。新的阻碍酚取代三嗪类包括一种三芳基-1,3,5-三嗪，其中芳基之一被一个包含阻碍酚或是阻碍酚的基团取代，并进一步被一个羟基取代，无论是自由的还是被阻断形成潜在的稳定剂，位于连接三嗪的邻位。这些材料在适当的情况下可能形成寡聚物。本发明还公开了一种通过加入这种阻碍酚取代的三嗪来稳定材料的方法。
• Non-yellowing para-tertiary-alkyl phenyl substituted triazineand pyrimidine ultraviolet light absorbers
  申请人：CYTEC Industries Corp.

  公开号：US20010031867A1

  公开（公告）日：2001-10-18

  This invention relates generally to para-tertiary alkyl phenyl substituted pyrimidines and triazines and the use thereof to protect against degradation by environmental forces, inclusive of ultraviolet light, actinic radiation, oxidation, moisture, atmospheric pollutants and combinations thereof. The new class of para-tertiary alkyl phenyl substituted pyrimidines and triazines includes two tertiary alkylated phenyl groups, and a resorcinol or substituted resocinol group attached to the triazine or pyrimidine ring. These materials may, under the appropriate circumstances, be bonded to formulations comprising coatings, polymers, resins, organic compounds and the like via reaction of the bondable functionality with the materials of the formulation. A method for stabilizing a material by incorporating such para-tertiary alkyl phenyl substituted pyrimidines and triazines is also disclosed.

  本发明涉及对抗环境力量（包括紫外线、光化学辐射、氧化、湿气、大气污染物和其组合）的降解的对位三级烷基苯基取代嘧啶和三嗪类化合物及其使用。新的对位三级烷基苯基取代嘧啶和三嗪类化合物包括两个三级烷基化的苯基团，以及连接到三嗪或嘧啶环上的间苯二酚或取代间苯二酚基团。在适当的情况下，这些材料可以通过可粘接的官能团与涂料、聚合物、树脂、有机化合物等配方材料反应而被粘附在一起。本发明还公开了一种通过加入这种对位三级烷基苯基取代嘧啶和三嗪类化合物来稳定材料的方法。
• Process for making triazine UV absorbers using Lewis acids and reaction promoters
  申请人：CYTEC Industries Corp.

  公开号：US20020013463A1

  公开（公告）日：2002-01-31

  It has been now surprisingly discovered after extensive research that 2-halo-4,6-bisaryl-1,3,5-triazine can be prepared with unprecedented selectivity, efficiency, mild conditions, and in high yield by the reaction of cyanuric halide with aromatics in the presence of at least one Lewis acid and at least one reaction promoter. This reaction is also unprecedently general as a variety of aromatics can be used to produce a wide selection of 2-halo-4,6-bisaryl-1,3,5-triazines. The novel approach includes the use of the reaction promoters in combination with at least one Lewis acid under certain reaction conditions to promote the formation of 2-halo-4,6-bisaryl-1,3,5-triazine compounds from cyanuric halide. Preferably, the Lewis acids and reaction promoters are combined to form a complex. 2-Halo-4,6-bisaryl-1,3,5-triazines are key intermediates for making 2-(2-oxyaryl)-4,6-bisaryl-1,3,5-triazine class of UV absorbers.

  经过广泛的研究，惊人地发现了一种前所未有的选择性、效率、温和条件和高产率的方法，通过氰尿酸卤化物与芳香族化合物在至少一种路易斯酸和至少一种反应促进剂的存在下反应，制备2-卤代-4,6-双芳基-1,3,5-三嗪。这种反应也是前所未有的普适性，因为可以使用各种芳香族化合物来产生广泛的2-卤代-4,6-双芳基-1,3,5-三嗪选择。新方法包括在特定反应条件下使用反应促进剂与至少一种路易斯酸相结合，促进从氰尿酸卤化物中形成2-卤代-4,6-双芳基-1,3,5-三嗪化合物。最好是将路易斯酸和反应促进剂组合成复合物。2-卤代-4,6-双芳基-1,3,5-三嗪是制造2-(2-氧基芳基)-4,6-双芳基-1,3,5-三嗪类紫外线吸收剂的关键中间体。
• Process for Making Trisaryl Triazine UV Absorbers Using Lewis Acids and Reaction Promoters
  申请人：Gupta B. Ram

  公开号：US20070015920A1

  公开（公告）日：2007-01-18

  It has been now surprisingly discovered after extensive research that 2-halo-4,6-bisaryl-1,3,5-triazine can be prepared with unprecedented selectivity, efficiency, mild conditions, and in high yield by the reaction of cyanuric halide with aromatics in the presence of at least one Lewis acid and at least one reaction promoter. This reaction is also unprecedently general as a variety of aromatics can be used to produce a wide selection of 2-halo-4,6-bisaryl-1,3,5-triazines. The novel approach includes the use of the reaction promoters in combination with at least one Lewis acid under certain reaction conditions to promote the formation of 2-halo-4,6-bisaryl-1,3,5-triazine compounds from cyanuric halide. Preferably, the Lewis acids and reaction promoter's are combined to form a complex 2-Halo-4,6-bisaryl-1,3,5-triazines are key intermediates for making 2-(2-oxyaryl)-4,6-bisaryl-1,3,5-triazine class of UV absorbers.

  经过广泛的研究，惊奇地发现可以通过氰尿酸卤化物与芳香族化合物在至少一种路易斯酸和至少一种反应促进剂的存在下反应，在温和的条件下高效、高产地选择性地制备2-卤代-4,6-双芳基-1,3,5-三嗪，这种反应也是前所未有的普遍的，因为各种芳香族化合物都可以用来生产各种2-卤代-4,6-双芳基-1,3,5-三嗪。新的方法包括在特定的反应条件下，使用反应促进剂与至少一种路易斯酸结合，促进从氰尿酸卤化物中形成2-卤代-4,6-双芳基-1,3,5-三嗪化合物。最好是将路易斯酸和反应促进剂组合形成复合物。2-卤代-4,6-双芳基-1,3,5-三嗪是制造2-(2-氧基芳基)-4,6-双芳基-1,3,5-三嗪类紫外线吸收剂的关键中间体。