[14-C]-methane | 2772-68-1

• 分子结构分类: 有机化合物 - 碳氢化合物 - 饱和烃
• 英文名称: [14-C]-methane
• 英文别名: (14C)methane；[¹⁴C]methane；[¹⁴C]Methan；<14C>-Methan；Methan-14C；Methan-C14；Carbon-14；carbane
• CAS: 2772-68-1
• 化学式: CH₄
• 分子量: 18.0318
• InChiKey: VNWKTOKETHGBQD-NJFSPNSNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  1
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

ADMET

毒理性

• 致癌物分类

内化的发射β粒子的放射性核素对人类是致癌的（第1组）（L2150）。碳-14经历β衰变。

Internalized radionuclides that emit β particles are carcinogenic to humans (Group 1) (L2150). Carbon-14 undergoes beta decay.

来源:Toxin and Toxin Target Database (T3DB)

毒理性

• 暴露途径

摄入、吸入、刺伤、伤口、皮肤污染（吸收）

Ingestion, inhalation, puncture, wound, skin contamination (absorption)

来源:Toxin and Toxin Target Database (T3DB)

反应信息

• 作为反应物：
  描述：

  [14-C]-methane 生成 alkaline earth salt of/the/ methylsulfuric acid
  参考文献：
  名称：

  制备碳十四标记的甲烷和四氯化碳。

  摘要：

  DOI：

  10.1021/ja01191a110
• 作为产物：
  描述：

  苯胺 生成 [14-C]-methane
  参考文献：
  名称：

  Yankwich; Rollefson; Norris, Journal of Chemical Physics, 1946, vol. 14, p. 135

  摘要：

  DOI：

文献信息

• Turnover of propionate in methanogenic paddy soil
  作者：N Krylova

  DOI：10.1016/s0168-6496(97)00017-2

  日期：1997.6

  Samples from planted Italian paddy soil exhibited most probable numbers (MPN) of about 10(7) anaerobic propionate utilizers. In anoxic soil slurries that were either unamended or amended with rice straw production of CH4 was measured together with concentrations of H-2, acetate and propionate. After a lag phase, during which ferric iron was depleted, CH4 was produced at a constant rate which was slightly higher in the straw-amended than in the unamended soil. Propionate concentrations were relatively low at about 5-15 mu M. However, in the straw-amended soil propionate transiently accumulated to about 35 mu M just after onset of methanogenesis. During the period of propionate accumulation Ha partial pressures were elevated and the Gibbs free energy (Delta G) of propionate consumption to acetate, bicarbonate and H-2 was endergonic or higher than -3 kJ mol(-1) propionate. Propionate concentrations decreased again when the BG decreased to more negative values. In unamended paddy soil, propionate did not accumulate transiently and Delta G was always < -6 kJ mol(-1) propionate. Propionate radiolabelled in the C-1 or C-2 position was utilized with turnover times of 30-60 min. Propionate turnover rates approximately accounted for the rates of H-2/CO2-dependent methanogenesis that were measured in experiments with [C-14]bicarbonate. The only radioactive product of [1-C-14]propionate was (CO2)-C-14. However, [2-C-14]propionate was converted to radioactive acetate, CO2 and CH4. This observation indicates that propionate was consumed via a randomizing pathway to CO2 and acetate, the latter being then further degraded by acetotrophic methanogens to CO2 and CH4. Turnover of [1-C-14]propionate was almost completely inhibited by high H-2 concentrations, chloroform or molybdate. The MPN of bacteria. that utilized propionate either in syntrophy with methanogens or by reduction of sulfate was identical. All these observations suggest that propionate was consumed by a syntrophic randomizing pathway, probably by bacteria that have also the capacity to reduce sulfate.
• MALINA, JOSEPH F. (JR);CRAVEIRO, FERNANDO, J. HAZARDOUS MATER., 24,(1990) N-3, C. 279-280
  作者：MALINA, JOSEPH F. (JR)、CRAVEIRO, FERNANDO

  DOI：——

  日期：——
• ELBERT, THOMAS;MATUCHA, MIROSLAV, J. LABELL. COMPOUNDS AND RADIOPHARM., 28,(1990) N2, C. 1449-1453
  作者：ELBERT, THOMAS、MATUCHA, MIROSLAV

  DOI：——

  日期：——
• Yankwich; Rollefson; Norris, Journal of Chemical Physics, 1946, vol. 14, p. 135
  作者：Yankwich、Rollefson、Norris

  DOI：——

  日期：——
• The Preparation of Carbon Fourteen Labeled Methane and Carbon Tetrachloride
  作者：William H. Beamer

  DOI：10.1021/ja01191a110

  日期：1948.11