1-(4-dimethylamino-phenyl)-3,3-diphenyl-propan-1-one | 102560-70-3

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 直链 1,3-二芳基丙烷
• 英文名称: 1-(4-dimethylamino-phenyl)-3,3-diphenyl-propan-1-one
• 英文别名: 1-(4-Dimethylamino-phenyl)-3,3-diphenyl-propan-1-on；1-[4-(Dimethylamino)phenyl]-3,3-diphenylpropan-1-one
• CAS: 102560-70-3
• 化学式: C₂₃H₂₃NO
• 分子量: 329.442
• InChiKey: ADYFLNMOMJXKMQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  25
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  phenylmagnesium bromide 、 alkaline earth salt of/the/ methylsulfuric acid 生成 1-(4-dimethylamino-phenyl)-3,3-diphenyl-propan-1-one
  参考文献：
  名称：

  Smolanka, 1957, vol. 18, p. 15,16

  摘要：

  DOI：

文献信息

• Synthesis of Substituted Aryl Ketones by Addition of Alcohols to Alkynes Using Amberlyst-15/Ionic Liquid as a Recyclable Catalytic System
  作者：Bhalchandra Bhanage、Kishor Wagh

  DOI：10.1055/s-0034-1380142

  日期：——

  A highly efficient protocol for the synthesis of substituted aryl ketones by using Amberlyst-15 immobilized in [Bmim][PF6] ionic liquid has been firstly developed. The present protocol works under metal-free, solvent-free, mild reaction conditions with 100% atom efficiency. The various aryl ketones were obtained in good to excellent yields. The developed catalytic system was recycled efficiently up to five cycles without significant loss in catalytic activity.