2,4-Dimethoxy-3-isopropyl-benzaldehyde | 144707-45-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,4-Dimethoxy-3-isopropyl-benzaldehyde
• 英文别名: 2,4-Dimethoxy-3-isopropylbenzaldehyde；2,4-dimethoxy-3-propan-2-ylbenzaldehyde
• CAS: 144707-45-9
• 化学式: C₁₂H₁₆O₃
• 分子量: 208.257
• InChiKey: JKLVCOSTMWHDKH-UHFFFAOYSA-N

物化性质

• 沸点：
  328.5±42.0 °C(Predicted)
• 密度：
  1.045±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2,4-Dimethoxy-3-isopropyl-benzaldehyde 在 吡啶 、 sodium tetrahydroborate 、 三溴化磷 作用下， 以 甲醇 、 苯 为溶剂， 反应 3.2h， 生成 2,4-Dimethoxy-3-isopropylbenzyl bromide
  参考文献：
  名称：

  Burnell, Robert H.; Caron, Stephane, Canadian Journal of Chemistry, 1992, vol. 70, # 5, p. 1446 - 1454

  摘要：

  DOI：
• 作为产物：
  描述：

  1,3-二甲氧基-2-(1-羟基-1-甲基乙基)苯 在 palladium on activated charcoal 18-冠醚-6 、 氢气 、 magnesium 、 溶剂黄146 、 间氯过氧苯甲酸 、 potassium bromide 作用下， 以 乙醚 、 二氯甲烷 为溶剂， 反应 21.58h， 生成 2,4-Dimethoxy-3-isopropyl-benzaldehyde
  参考文献：
  名称：

  Burnell, Robert H.; Caron, Stephane, Canadian Journal of Chemistry, 1992, vol. 70, # 5, p. 1446 - 1454

  摘要：

  DOI：

文献信息

• Asymmetric Reaction Catalyst and Method for Preparing Optically Active Compound Using the Same
  申请人：Kobayashi Shu

  公开号：US20070265472A1

  公开（公告）日：2007-11-15

  An asymmetric reaction catalyst is obtained by mixing a pentavalent niobium compound and an optically active triol or tetraol having a binaphthol structure of R or S configuration, and the triol is represented by the following formula: (wherein, Y is divalent hydrocarbon and R 1 is a hydrogen atom, a halogen atom, a trifluoromethyl group, or an alkyl group or alkoxy group having at most 4 carbons).

  一种不对称反应催化剂是通过混合五价铌化合物和具有R或S构型的具有二萘酚结构的光学活性三元醇或四元醇获得的，其中三元醇由以下公式表示：（其中，Y为双价碳氢化合物，R1为氢原子、卤素原子、三氟甲基基团或最多具有4个碳的烷基或烷氧基）。
• ASYMMETRIC REACTION CATALYST AND METHOD FOR PREPARING OPTICALLY ACTIVE COMPOUND USING THE SAME
  申请人：Kobayashi Shu

  公开号：US20100029968A1

  公开（公告）日：2010-02-04

  An asymmetric reaction catalyst is obtained by mixing a pentavalent niobium compound and an optically active triol or tetraol having a binaphthol structure of R or s configuration, and the triol is represented by the following formula: wherein, Y is divalent hydrocarbon and R I is a hydrogen atom, a halogen atom, a trifluoromethyl group, or an alkyl group or alkoxy group having at most 4 carbons.

  一种不对称反应催化剂是通过混合五价铌化合物和具有R或s构型的二萘酚结构的手性三醇或四醇而获得的，其中三醇的表示式如下： 其中，Y为二价碳氢化合物，RI为氢原子、卤素原子、三氟甲基基团或最多具有4个碳的烷基或烷氧基。
• Syntheses, constitutions and properties of stentorin and isostentorin
  作者：H. Falk、E. Mayr

  DOI：10.1007/bf00807060

  日期：1995.12

  Stentorin and Isostentorin were synthesized from 2-isopropyl-1,3,6,8-tetrahydroxyanthrone by dimerization and chromatographic separation of the resulting regioisomers. The anthrone was prepared in four steps starting from easily available properly substituted benzene derivatives; the overall yield of the stentorins was 11%. The constitutions of stentorin and isostentorin could be unequivocally assigned from the H-1 NMR spectra of their potassium salts and were found to be in agreement with those derived recently by means of a rational synthesis. The spectroscopic, dissociation, and acid-base properties in ground and excited states as well as the chiroptical properties of the human serum albumin complexes were investigated and discussed comparing them with respective data of hypericin, fringelite D, and the natural Stenter pigment.
• ASYMMETRIC REACTION CATALYST AND PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE COMPOUNDS WITH THE SAME
  申请人：Japan Science and Technology Agency

  公开号：EP1724013B1

  公开（公告）日：2015-01-28
• US7667078B2
  申请人：——

  公开号：US7667078B2

  公开（公告）日：2010-02-23