Ethyl-2-ethyl-3-hydroxy-3-methylbutyrat | 18804-43-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Ethyl-2-ethyl-3-hydroxy-3-methylbutyrat
• 英文别名: 2-Ethyl-3-hydroxy-3-methyl-buttersaeureethylester；2-ethyl-3-hydroxy-3-methyl-butyric acid ethyl ester；2-Hydroxy-2-methyl-pentan-carbonsaeure-(3)-aethylester；2-Aethyl-3-hydroxy-3-methyl-buttersaeure-aethylester；β-Oxy-β-methyl-pentan-γ-carbonsaeure-aethylester；Ethyl 2-ethyl-3-hydroxy-3-methylbutanoate
• CAS: 18804-43-8
• 化学式: C₉H₁₈O₃
• 分子量: 174.24
• InChiKey: SZIOYYKKOXBUTA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  Ethyl-2-ethyl-3-hydroxy-3-methylbutyrat 在 lithium aluminium tetrahydride 作用下， 以 乙醚 为溶剂， 生成 2-Ethyl-3-methyl-1,3-butandiol
  参考文献：
  名称：

  从菊花中合成单萜内酯L。

  摘要：

  描述了从菊花中分离出的内酯成分 [(Z)-5-ethylidene-5,6-dihydro-3,6,6-trimethyl-2H-pyran-2-one] 的合成。5-乙基-5,6-二氢-5-羟基-3,6,6-三甲基-2H-吡喃-2-酮衍生自5-乙基-5,6-二氢-6,6-二甲基-3的脱水-苯硫基-2H-吡喃-2-one 通过甲基化、氧化、[2,3] σ 重排和皂化，得到几何异构体 [(E)-5-亚乙基] 内酯。亚乙基侧链的光化学异构化提供了天然内酯。两种异构体中亚乙基的几何结构已经严格确定。

  DOI：

  10.1246/bcsj.51.3011
• 作为产物：
  描述：

  丁酸乙酯 、 丙酮 生成 Ethyl-2-ethyl-3-hydroxy-3-methylbutyrat
  参考文献：
  名称：

  A Convenient Preparation and Utilization of Lithium Dialkylamides

  摘要：

  DOI：

  10.1055/s-1979-28721

文献信息

• Grignard, Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1902, vol. 134, p. 851
  作者：Grignard

  DOI：——

  日期：——
• Diagnostics of phonological lexical processing: Pseudohomophone naming advantages, disadvantages, and base-word frequency effects
  作者：Ron Borowsky、William J. Owen、Michael E. J. Masson

  DOI：10.3758/bf03195781

  日期：2002.9

  Phonological lexical access has been investigated by examining,both a pseudohomophone (e.g., brane) base-word frequency effect and a pseudohomophone advantage over pronounceable nonwords (e.g., frane) in a single mixed block of naming trials. With a new set of pseudohomophones and nonwords presented in a mixed block, we replicated the standard finding in the naming literature: no reliable base-word frequency effect, and a pseudohomophone advantage. However, for this and two of three other sets of stimuli-those of McCann and Besner (1987), Seidenberg, Petersen, MacDonald, and Plaut (1996), and Herdman, LeFevre, and Greenham (1996), respectively-reliable effects of base-word frequency on pseudohomophone naming latency were found when pseudohomophones were presented in pure blocks prior to nonwords. Three of the four stimulus sets tested produced a pseudohomophone naming disadvantage when pseudohomophones were presented prior to nonwords. When nonwords were presented first, these effects were diminished. A strategy-based scaling account of the data is argued to provide a better explanation of the data than is the criterion-homogenization theory (Lupker, Brown, & Colombo, 1997).
• Blaise; Maire, Annales de Chimie (Cachan, France), 1908, vol. <8>15, p. 570
  作者：Blaise、Maire

  DOI：——

  日期：——
• Huston; Goerner; Gyoergy, Journal of the American Chemical Society, 1948, vol. 70, p. 390
  作者：Huston、Goerner、Gyoergy

  DOI：——

  日期：——
• A Convenient Preparation and Utilization of Lithium Dialkylamides
  作者：F. Gaudemar-Bardone、M. Gaudemar

  DOI：10.1055/s-1979-28721

  日期：——