(E)-9-hexadecenyl acetate | 56218-69-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (E)-9-hexadecenyl acetate
• 英文别名: (E)-9-Hexadecenylacetat；acetoxy-1 hexadecene-9；9-hexadecenyl acetate；acetic acid hexadec-9-enyl ester；Essigsaeure-hexadec-9-enylester；[(E)-hexadec-9-enyl] acetate
• CAS: 56218-69-0
• 化学式: C₁₈H₃₄O₂
• 分子量: 282.467
• InChiKey: VAKBQCYSUVICLV-CMDGGOBGSA-N

物化性质

• 保留指数：
  1984.6

计算性质

• 辛醇/水分配系数(LogP)：
  6.8
• 重原子数：
  20
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  二甲基二硫 、 (E)-9-hexadecenyl acetate 在 碘 作用下， 以 乙醚 、 正己烷 为溶剂， 生成
  参考文献：
  名称：

  Determination of double bond position in mono-unsaturated acetates by mass spectrometry of dimethyl disulfide adducts

  摘要：

  DOI：

  10.1021/ac00257a003
• 作为产物：
  描述：

  (E)-1-bromo-oct-2-ene 在 lithium aluminium tetrahydride 、 正丁基锂 、 对甲苯磺酸 作用下， 以 吡啶 、 甲醇 、 乙醚 、 水 为溶剂， 反应 27.5h， 生成 (E)-9-hexadecenyl acetate
  参考文献：
  名称：

  信息素，XXVIII。立体定向合成（E）-烯烃共聚物Schmetterlingspheromone

  摘要：

  Es wird eine Allgemeine立体选择性合成（E）-单链烯键式信息素和链烯酮二乙基膦酸酯和烯丙基二乙基膦酸酯和纳米二烯化锂。

  DOI：

  10.1002/cber.19801130330

文献信息

• What is the Optimal Evaluation Time of the QT Dispersion After Acute Myocardial Infarction for the Risk Stratification?
  作者：G. Kabakci、O. Önalan、M. Kemal Batur、A. Yildirir、R. Çağrikul、T. Açil、L. Tokgözoğlu、A. Oto、F. Özmen、S. Kes

  DOI：10.1177/000331970105200704

  日期：2001.7

  The sequential changes of the corrected QT dispersion (QTcD) were studied in 136 patients 1 day to 30 days after a transmural acute myocardial infarction (AMI) to investigate the optimal measurement time of QT dispersion for risk stratification. The study group included 136 patients (89 men; mean age, 57 ±10 years) with transmural AMI who were treated with throm bolytics (Tr+ group, n = 73) or not (Tr- group, n = 63) and 65 healthy controls (43 men; mean age, 56 ±7 years). Fourteen patients in whom ventricular tachycardia (VT), ventricular fibrilla tion (VF), or sudden cardiac death developed during the 30-day period were also evaluated as major cardiac arrhythmia (MCA) group. ECGs were obtained for each patient on days 1, 3, 5, 10, 15, and 30 after AMI. QTc dispersion in patients with AMI (for every period of QTcD after MI) was significantly more prolonged than in normal controls (49.3 ± 16.3 ms) (p < 0.001). QTcD was significantly greater in patients without thrombolytics than in patients with thrombolytics for every period (days 1, 3, 5, 10, 15, and 30) of QTcD after MI (p < 0.001). The mean of QTcD was significantly greater in patients with MCA than in patients without MCA group for every period (days 1, 3, 5, 10, 15, and 30) of QTcD after MI (p < 0.05). Maximal QTcD was seen on day 10 (p < 0.05 1st vs day 10 for each group) after myocardial infarction, and then reached a plateau for an each group. The ideal time to measure the QTD for risk stratification is at least 10 days after AMI.

  研究了136例透壁性急性心肌梗死（AMI）患者在接受溶栓治疗（Tr+组，n = 73）或不接受溶栓治疗（Tr-组，n = 63）后1天至30天内校正QT离散度（QTcD）的序贯变化，以探讨QT离散度测量时间对风险分层的最佳时间。研究组包括136例透壁性AMI患者（89名男性；平均年龄，57 ±10岁）和65名健康对照者（43名男性；平均年龄，56 ±7岁）。在30天内发生室性心动过速（VT）、心室颤动（VF）或心脏猝死的14例患者也被评估为重大心律失常（MCA）组。AMI后1、3、5、10、15和30天分别获得每位患者的ECG。AMI患者QTcD（MI后每个QTcD期间）较正常对照组明显延长（49.3 ± 16.3 ms）（p < 0.001）。MI后每个时期（1、3、5、10、15和30天）未接受溶栓治疗的患者QTcD显著高于接受溶栓治疗的患者（p < 0.001）。QTcD平均值在MCA组患者中较非MCA组患者每个时期（1、3、5、10、15和30天）显著升高（p < 0.05）。心肌梗死后第10天QTcD最大（p < 0.05，第1天与第10天各组比较），之后达到平台期。AMI后至少10天是测量QTD进行风险分层的理想时间。
• Synthesis of insect sex pheromones and their homologues. 2. A convenient method for synthesizing (Z)-alkenols and their acetates.
  作者：Michio HORIIKE、Masaru TANOUCHI、Chisato HIRANO

  DOI：10.1271/bbb1961.44.257

  日期：——

  (Z)-Alkenols and Their acetates have been synthesized by the Wittig reaction of (ω-hydroxyalkyl)triphenylphosphonium salts with alkanals by a convenient procedure. The geometrical purity of the products was evaluated to be no less than 95% of the (Z)-configu-ration by means of GLC with a glass capillary column coated with CHDMS.

  通过一种简便的方法，利用Wittig反应将（ω-羟基烷基）三苯基膦盐与烷基醛反应，合成了（Z）-烯醇及其乙酸酯。通过涂有CHDMS的玻璃毛细管柱进行GC分析，评估产物的几何纯度不小于95%的（Z）构型。
• PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS
  申请人：PROVIVI, INC.

  公开号：US20170137365A1

  公开（公告）日：2017-05-18

  In one aspect, the invention provides a method for synthesizing a fatty olefin derivative. The method includes: a) contacting an olefin according to Formula I with a metathesis reaction partner according to Formula IIb in the presence of a metathesis catalyst under conditions sufficient to form a metathesis product according to Formula IIIb: and b) converting the metathesis product to the fatty olefin derivative. Each R 1 is independently selected from H, C 1-18 alkyl, and C 2-18 alkenyl; R 2b is C 1-8 alkyl; subscript y is an integer ranging from 0 to 17; and subscript z is an integer ranging from 0 to 17. In certain embodiments, the metathesis catalyst is a tungsten catalyst or a molybdenum catalyst. In various embodiments, the fatty olefin derivative is a pheromone. Pheromone compositions and methods of using them are also described.

  在一个方面，该发明提供了一种合成脂肪烯衍生物的方法。该方法包括：a）在存在一种烯烃催化剂的条件下，将符合式I的烯烃与符合式IIb的交换反应伙伴接触，以形成符合式IIIb的交换产物；并b）将交换产物转化为脂肪烯衍生物。每个R1独立地选择自H、C1-18烷基和C2-18烯基；R2为C1-8烷基；下标y为0至17之间的整数；下标z为0至17之间的整数。在某些实施方式中，交换催化剂为钨催化剂或钼催化剂。在各种实施方式中，脂肪烯衍生物为信息素。还描述了信息素组合物及其使用方法。
• AGRICULTURAL PHEROMONE COMPOSITIONS COMPRISING POSITIONAL ISOMERS
  申请人：PROVIVI, INC.

  公开号：US20170135343A1

  公开（公告）日：2017-05-18

  The present disclosure provides pheromone compositions. In some aspects, the compositions taught herein comprise a pheromone chemically corresponding to the pheromone naturally produced by a given insect, along with at least one positional isomer of said pheromone. In various aspects, pheromone compositions of the present disclosure are able to modulate the response of the insect based on the ratio of natural pheromone to its positional isomer.

  本公开提供信息素组合物。在某些方面，本文所教授的组合物包括一种与某种昆虫自然产生的信息素在化学上相对应的信息素，以及至少一种该信息素的位置异构体。在各个方面，本公开的信息素组合物能够通过自然信息素与其位置异构体的比例来调节昆虫的反应。
• Metathese d'acetates d'alcools ω-insatures
  作者：Jacques Levisalles、Didier Villemin

  DOI：10.1016/0040-4020(80)80163-3

  日期：1980.1

  Esters of alkenoic acids, including insect pheromones as examples, have been synthesized using alkene metathesis reactions.

  链烯酸的酯，包括昆虫信息素作为例子，已经使用链烯复分解反应合成。