(R)-linalyl oxide | 286428-24-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧唑烯
• 英文名称: (R)-linalyl oxide
• 英文别名: 2-[(5R)-5-ethenyl-5-methyloxolan-2-yl]propan-2-ol
• CAS: 286428-24-8
• 化学式: C₁₀H₁₈O₂
• 分子量: 170.252
• InChiKey: BRHDDEIRQPDPMG-HTLJXXAVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (R)-linalyl oxide 在 2-甲基-2-丁烯 、 dimethyl sulfide borane 、 sodium acetate 作用下， 以 乙醚 为溶剂， 反应 7.0h， 生成 (2RS,5SR)-(5-(1-acetoxy-1-methylethyl)-2-methyl-perhydro-2-furanyl)acetaldehyde
  参考文献：
  名称：

  Mahboobi, Siavosh; Koller, Markus; Schollmeyer, Dieter, Monatshefte fur Chemie, 2000, vol. 131, # 4, p. 383 - 392

  摘要：

  DOI：
• 作为产物：
  描述：

  (S)-芳樟醇 在 间氯过氧苯甲酸 、 三氯乙酸 作用下， 生成 2,2,6-trimethyl-6-vinyltetrahydropyran-3-ol 、 (R)-linalyl oxide
  参考文献：
  名称：

  The use of acyclic monoterpenes in the preparation of β-pyrones: Synthesis of the right-hand fragment of Usneoidone E

  摘要：

  The right hand fragment, 36, of Usneoidone E, 1, a powerful antiviral and antitumoural agent has been synthesized from the beta-pyrone 32. Using linalool as starting material, a 2,2,6,6-tetrasubstituted dihydropyrane 20, precursor of 32 and 33, was prepared. 20 was also synthesized From geranyl acetate through selenide 7, and is a versatile precursor for the synthesis of tetaprenyltoluquinols. Unambiguous C-13 NMR assignment has been done by 2D correlations.

  DOI：

  10.1016/0040-4020(95)00084-l

文献信息

• The use of acyclic monoterpenes in the preparation of β-pyrones: Synthesis of the right-hand fragment of Usneoidone E
  作者：Julio G. Urones、David Díez、Isidro S. Marcos、Pilar Basabe、Anna M. Lithgow、Rosalina F. Moro、Narciso M. Garrido、Ricardo Escarcena

  DOI：10.1016/0040-4020(95)00084-l

  日期：1995.3

  The right hand fragment, 36, of Usneoidone E, 1, a powerful antiviral and antitumoural agent has been synthesized from the beta-pyrone 32. Using linalool as starting material, a 2,2,6,6-tetrasubstituted dihydropyrane 20, precursor of 32 and 33, was prepared. 20 was also synthesized From geranyl acetate through selenide 7, and is a versatile precursor for the synthesis of tetaprenyltoluquinols. Unambiguous C-13 NMR assignment has been done by 2D correlations.
• Mahboobi, Siavosh; Koller, Markus; Schollmeyer, Dieter, Monatshefte fur Chemie, 2000, vol. 131, # 4, p. 383 - 392
  作者：Mahboobi, Siavosh、Koller, Markus、Schollmeyer, Dieter

  DOI：——

  日期：——