(2,4-dihydroxy-3-methyl-phenyl)-phenyl-methanone | 52117-23-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (2,4-dihydroxy-3-methyl-phenyl)-phenyl-methanone
• 英文别名: 2,4-dihydroxy-3-methylbenzophenone；2,4-dihydroxy-3-methyl-benzophenone；2,4-Dihydroxy-3-methyl-benzophenon；(2,4-Dihydroxy-3-methylphenyl)(phenyl)methanone；(2,4-dihydroxy-3-methylphenyl)-phenylmethanone
• CAS: 52117-23-4
• 化学式: C₁₄H₁₂O₃
• 分子量: 228.247
• InChiKey: NEANPRQTNOPNGE-UHFFFAOYSA-N

物化性质

• 熔点：
  177°C
• 沸点：
  427.9±14.0 °C(Predicted)
• 密度：
  1.263±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  (2,4-dihydroxy-3-methyl-phenyl)-phenyl-methanone 在 硫酸 、 溴 、 sodium acetate 、 potassium carbonate 、 N,N-二甲基苯胺 、 三乙胺 作用下， 以 溶剂黄146 、 丙酮 为溶剂， 反应 16.25h， 生成 Acetic acid 6-(2,3-dibromo-propyl)-8-methyl-2-oxo-3,4-diphenyl-2H-chromen-7-yl ester
  参考文献：
  名称：

  Desai, S. M.; Trivedi, K. N., Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1985, vol. 24, p. 47 - 50

  摘要：

  DOI：
• 作为产物：
  描述：

  2-甲基-3-甲氧基苯酚 在 盐酸 、 乙醚 、 氢碘酸 、 zinc(II) chloride 作用下， 生成 (2,4-dihydroxy-3-methyl-phenyl)-phenyl-methanone
  参考文献：
  名称：

  224.羟基羰基化合物。第八部分。2：6-二羟基甲苯的某些衍生物

  摘要：

  DOI：

  10.1039/jr9320001689

文献信息

• Acetophenone potentiators of metabotropic glutamate receptors
  申请人：Cube V. Rowena

  公开号：US20050288346A1

  公开（公告）日：2005-12-29

  The present invention is directed to compounds which are potentiators of metabotropic glutamate receptors, including the mGluR2 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which metabotropic glutamate receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which metabotropic glutamate receptors are involved.

  本发明涉及激活型代谢型谷氨酸受体的化合物，包括mGluR2受体，适用于治疗或预防与谷氨酸功能障碍相关的神经和精神障碍以及涉及代谢型谷氨酸受体的疾病。本发明还涉及包含这些化合物的制药组合物以及使用这些化合物和组合物预防或治疗涉及代谢型谷氨酸受体的疾病。
• UV-light stabilizer composition comprising cyclic aliphatic epoxy, UV screener, and polyalkyldipiperidine (HALS) compounds
  申请人：GENERAL ELECTRIC COMPANY

  公开号：EP0240723A2

  公开（公告）日：1987-10-14

  A cycloaliphatic epoxy compound in combination with a 2-hydroxy-substituted benzophenone compound and a polyalkyl-substituted dipiperidine compound provides a UV stabilizer that exhibits synergistic behavior. The compounds can be formulated into a composition that is coated on, or impregnated into, the surface of a plastic article or, alternatively, they can be incorporated into a thermoplastic composition which can be thereafter molded into a shaped article. The stabilizer combination succeeds in upgrading the resistance of polyphenylene ether resins and blends against the photo-deteriorative effects of sunlight and bright indoor light, for example, fluorescent lighting.

  一种环脂族环氧化合物与一种 2-羟基取代的二苯甲酮化合物和一种多烷基取代的二哌啶化合物相结合，可提供一种具有协同作用的紫外线稳定剂。这些化合物可以配制成涂覆在塑料制品表面或浸渍在塑料制品表面的组合物，也可以加入热塑性组合物中，然后模塑成成型制品。这种稳定剂组合可成功提高聚苯醚树脂和混合物的抗光性，使其免受阳光和室内强光（如荧光灯）的光劣化影响。
• POLYMER ELECTROLYTE MATERIAL, POLYMER ELECTROLYTE PART, MEMBRANE ELECTRODE COMPOSITE AND POLYMER ELECTROLYTE TYPE FUEL CELL
  申请人：TORAY INDUSTRIES, INC.

  公开号：EP1619735A1

  公开（公告）日：2006-01-25

  The invention aims to provide a polymer electrolytic material excellent in proton conductivity and also excellent in fuel shutting property, and accordingly provide a polymer electrolytic fuel cell with a high efficiency. That is, the invention provides a polymer electrolytic material having an unfreezable water ratio Rw1 defined by the following expression (S1) in a range of 20 to 100% by weight in hydrated state: Rw1=[Wnf/(Wfc+Wnf)]×100 in which Wnf represents the unfreezable water content per 1 g of the polymer electrolytic material in dry state and Wfc represents the low freezing point water content per 1 g of the polymer electrolytic material in dry state.

  本发明的目的是提供一种质子传导性能优异且燃料关断性能优异的聚合物电解材料，从而提供一种具有高效率的聚合物电解燃料电池。 也就是说，本发明提供了一种聚合物电解材料，在水合状态下，其不冻水比率 Rw1 由以下表达式（S1）定义，按重量计，范围为 20%至 100%：Rw1=[Wnf/(Wfc+Wnf)]×100 其中，Wnf 表示每 1 克聚合物电解材料在干燥状态下的不冻水含量，Wfc 表示每 1 克聚合物电解材料在干燥状态下的低冰点水含量。
• Polymer electrolyte material, polymer electrolyte part, membrane electrode composite and polymer electrolyte type fuel cell
  申请人：Adachi Shinya

  公开号：US20060180796A1

  公开（公告）日：2006-08-17

  The invention aims to provide a polymer electrolytic material excellent in proton conductivity and also excellent in fuel shutting property, and accordingly provide a polymer electrolytic fuel cell with a high efficiency. That is, the invention provides a polymer electrolytic material having an unfreezable water ratio Rw1 defined by the following expression (S1) in a range of 20 to 100% by weight in hydrated state: Rw 1=[ Wnf/ ( Wfc+Wnf )]×100   (S1) in which Wnf represents the unfreezable water content per 1 g of the polymer electrolytic material in dry state and Wfc represents the low freezing point water content per 1 g of the polymer electrolytic material in dry state.

  本发明的目的是提供一种质子传导性能优异且燃料关断性能优异的聚合物电解材料，从而提供一种具有高效率的聚合物电解燃料电池。也就是说，本发明提供了一种聚合物电解材料，在水合状态下，其不冻水比率 Rw1 由以下表达式（S1）定义，按重量计，范围为 20%至 100%： Rw 1=[ Wnf/ ( Wfc+Wnf )]×100 (S1) 其中，Wnf 表示每 1 克聚合物电解材料在干燥状态下的不冻含水量，Wfc 表示每 1 克聚合物电解材料在干燥状态下的低冰点含水量。
• [EN] ACETOPHENONE POTENTIATORS OF METABOTROPIC GLUTAMATE RECEPTORS<br/>[FR] POTENTIALISATEURS ACETOPHENONES DES RECEPTEURS METABOTROPIQUES DU GLUTAMATE
  申请人：MERCK & CO INC

  公开号：WO2004018386A3

  公开（公告）日：2004-11-25