-OH | 133472-83-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: -OH
• 英文别名: 4,4-bis[4-(benzyloxy)phenyl]pentanol；4,4-Bis(4-phenylmethoxyphenyl)pentan-1-ol
• CAS: 133472-83-0
• 化学式: C₃₁H₃₂O₃
• 分子量: 452.593
• InChiKey: UDDVBPRYEPIZHC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.1
• 重原子数：
  34
• 可旋转键数：
  11
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  38.7
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  -OH 在 4-二甲氨基吡啶 、 三乙胺 作用下， 以 二氯甲烷 、 二甲基亚砜 为溶剂， 反应 15.0h， 生成 N-methyl-4,4-bis(4-phenylmethoxyphenyl)pentan-1-amine
  参考文献：
  名称：

  Synthesis of a Series of Focally-Substituted Organothiol Dendrons

  摘要：

  The synthesis of new organothiol-functionalized dendrons of generation 1-4 is described. Several modifications to the original method for preparation of dendrons are detailed that were found to improve the yield and aid in scale-up. A particularly advantageous method for preparation of an aromatic thiol is reported and is employed in this reaction sequence. Several uses of these dendrons are anticipated and briefly described.

  DOI：

  10.1021/jo961527q
• 作为产物：
  描述：

  双酚酸 在 lithium aluminium tetrahydride 、 potassium carbonate 、 potassium iodide 作用下， 以 四氢呋喃 、 丙酮 为溶剂， 生成 -OH
  参考文献：
  名称：

  红景天苷类似物4,4-二-(4-羟苯基)戊基-β-D-吡喃葡萄糖苷及其合成方法

  摘要：

  本发明属于催化合成领域，具体涉及一种红景天苷类似物4,4‑二‑(4‑羟苯基)戊基‑β‑D‑吡喃葡萄糖苷及其制备方法。本发明所提供的4,4‑二‑(4‑羟苯基)戊基‑β‑D‑吡喃葡萄糖苷结构式为：。本发明提供的离子液体的合成仅需一步反应，且在离子液体合成反应中原料的原子得到100%的利用，是一个操作简便的原子经济性反应。本发明利用[Mmim][OSO2OM]/CH2Cl2作为共溶剂、Lewis酸作为催化剂组成的离子液体系作为绿色溶剂和催化剂，合成了一种新的红景天苷类似物，该合成方法环境友好、反应条件温和、后处理简单。

  公开号：

  CN107857783A

文献信息

• Hyperbranched macromolecules via a novel double-stage convergent growth approach
  作者：Karen L. Wooley、Craig J. Hawker、J. M. J. Frechet

  DOI：10.1021/ja00011a031

  日期：1991.5

  A novel double-stage convergent growth approach for the preparation of dendritic macromolecules is described. In the first stage, convergent growth with 4,4-bis(4'-hydroxyphenyl)pentanol as the building block is used to create symmetrical dendritic structures containing a large number of phenolic ''surface'' functionalities. In the second stage of growth, these polyphenolic dendritic macromolecules are utilized as cores for the attachment of other dendritic macromolecules, derived from 3,5-dihydroxybenzyl alcohol, that contain a single benzylic bromide reactive group at their focal point. This two-stage process affords hyperbranched spherical macromolecules consisting of a flexible inner core surrounded by a more rigid outer layer. The double-stage convergent growth approach allows for the preparation of larger dendrimers in less time and with greater ease than the single-stage approach while retaining the advantages of near monodispersity and ease of purification and characterization.
• Synthetic Approaches to an Isostructural Series of Redox-Active, Metal Tris(bipyridine) Core Dendrimers
  作者：Young-Rae Hong、Christopher B. Gorman

  DOI：10.1021/jo0351116

  日期：2003.11.1

  Several types of six-armed, metal tris(bipyridine) core dendrimers were synthesized. Bis-4,4'-alkoxy bipyridine dendrons were prepared and employed to make tris(bipyridine) dendrimers. Although the ruthenium-centered and iron-centered dendrimers displayed quasi-reversible cyclic voltammetry, the analogous cobalt-centered complex did not. The synthesis of 4,4'-disubstituted bipyridines containing -CH2OR groups proceeded in low yield. The reactions of the dicarbanion of 4,4'-dimethyl bipyridine prepared with LDA and mesylate, triflate, and bromide groups were found to result in no or poor yields of carbon-carbon bond formation. Use of KDA in place of LDA resulted in much higher yields of dendritic bipyridines.
• CN114890896
  申请人：——

  公开号：——

  公开（公告）日：——