bis(2-furylmethyl) trisulfide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 杂芳族化合物
• 英文名称: bis(2-furylmethyl) trisulfide
• 英文别名: Bis(2-furylmethyl)trisulfide；2-[(furan-2-ylmethyltrisulfanyl)methyl]furan
• 化学式: C₁₀H₁₀O₂S₃
• 分子量: 258.386
• InChiKey: XPRPVIPSHWDFBI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  102
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  bis(2-furylmethyl) trisulfide 、 三甲氧基磷 、 四氢呋喃 生成 2-(dimethoxyphosphorylsulfanylmethyl)furan
  参考文献：
  名称：

  HARPP D. N.; SMITH R. A., J. ORG. CHEM., 1979, 44, NO 23, 4140-4144

  摘要：

  DOI：
• 作为产物：
  描述：

  糠基硫醇 在 Di-1-imidazolyl-sulfid 作用下， 以60%的产率得到bis(2-furylmethyl) trisulfide
  参考文献：
  名称：

  Substituted organosulfur compounds and methods of using thereof

  摘要：

  本发明提供了取代二硫化物、三硫化物、四硫化物和五硫化物化合物及其组合物，以及利用它们用于治疗和/或预防细胞增殖性疾病的方法。本发明还提供了制备三硫化物化合物和组合物的方法。

  公开号：

  US20050261321A1

文献信息

• Some Novel Meatlike Aroma Compounds from the Reactions of Alkanediones with Hydrogen Sulfide and Furanthiols
  作者：Donald S. Mottram、Marta S. Madruga、Frank B. Whitfield

  DOI：10.1021/jf00049a035

  日期：1995.1

  The products of reactions of hydrogen sulfide with 2,3-butanedione and with 2,3-pentanedione in dilute ethanolic solution were analyzed by CC-MS and CC-odor port analysis. Components were also collected from the GC column and analyzed by H-1 NMR. Mercaptoketones were formed which readily oxidized to the corresponding disulfides with traces of mono- and trisulfides. When 2-methyl-3-furanthiol or 2-furylmethanethiol was added to the reaction mixtures, a series of disulfides containing alkanone, 2-methyl-3-furyl and 2-furanmethyl moieties were formed. Some of these compounds have been found recently in the volatiles of cooked meat and in meatlike model systems. GC-odor port evaluation of the components of the reaction systems showed that disulfides containing the 2-methyl-3-furyl group had meaty aromas, whereas those without this group were sulfurous or onion-like in character.